scholarly journals The Association Between Interleukin-10 Gene Promoter Polymorphism and Insulin Resistance in Type 2 Diabetes Mellitus

2016 ◽  
Vol 4 (3) ◽  
pp. 81 ◽  
Author(s):  
Sally Said Donia
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Gene Promoter ◽  
Interleukin 10 ◽  
Promoter Polymorphism ◽  
Gene Promoter Polymorphism

scholarly journals Association between Interleukin-10 promoter polymorphism with type 2 Diabetes mellitus

2021 ◽  
pp. 28-39
Author(s):  
Hafiz Umair Hassan ◽  
Rana Haider Ali ◽  
Hafiz Muhammad Usman Siddiq ◽  
Fahad Ahmed ◽  
Hafiz Hanan Taj ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Genetic Variants ◽  
Interleukin 10 ◽  
Promoter Polymorphism ◽  
Genotype Frequencies ◽  
Common Genetic Variants

Type 2 diabetes mellitus is a multifactorial illness triggered by a complicated interplay of various genetic variants with various environmental variables. The quantity of replicated common genetic variants associated with type 2 diabetes mellitus has increased rapidly with the recent genome-wide association (GWA) research. Major health issue in the public are type 2 diabetes mellitus (T2DM) is common throughout the world. Diabetes mellitus incidence is growing and is anticipated to affect 300 million individuals by 2025. Diabetes has been suggested to alter patterns of cytokine expression as an immune-dependent illness. Insulin resistance (IR) is a disease that results in less than anticipated biological impact of a specified insulin concentration. Insulin resistance and insulin secretion decreased are both defined pathophysiology of T2DM. One of the most alarming health issues of the 21st century is the spread of diabetes around the globe. Our goal in this study was to identify the role of IL-10 polymorphism in T2DM patients. The average age of 60 median patients with type 2 diabetes mellitus (31 males and 29 females) +-SD (45.91667 +-16.08799), fasting blood sugar (FBS) is +-SD (184.25 +-57.76387), hypertension (35 positive/25 negative) and 60 non-diabetic controls (32 males and 28 females) is +- SD (47.31667 +-15.13722). The group (T2DM patients and their control) had not a substantial distinction (P=0.33) and in each group (CC, TT, CT) there was a comparison between IL-10 gene polymorphism. T2DM patients and healthy individuals are not associated with the polymorphism of the gene IL-10 (SNP rs 3021097 (C/T). Keywords: Insulin, Diabetes Mellitis Type 2, Polymorphism, Interleukin-10, Genotype frequencies.

An Interleukin-10 Gene Promoter Polymorphism (−592A/C) Associated with Type 2 Diabetes: A North Indian Study

2012 ◽  
Vol 50 (7-8) ◽  
pp. 549-559 ◽  
Author(s):  
Madhukar Saxena ◽  
C. G. Agrawal ◽  
Hemant Kumar Bid ◽  
Monisha Banerjee
Keyword(s):  
Type 2 Diabetes ◽  
Gene Promoter ◽  
Interleukin 10 ◽  
Promoter Polymorphism ◽  
Indian Study ◽  
Gene Promoter Polymorphism

Direct association of a promoter polymorphism in the CD36/FAT fatty acid transporter gene with Type 2 diabetes mellitus and insulin resistance

2006 ◽  
Vol 23 (8) ◽  
pp. 907-911 ◽  
Author(s):  
E. Corpeleijn ◽  
C. J. H. van der Kallen ◽  
M. Kruijshoop ◽  
M. G. P. Magagnin ◽  
T. W. A. de Bruin ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Fatty Acid ◽  
Promoter Polymorphism ◽  
Transporter Gene ◽  
Direct Association ◽  
Fatty Acid Transporter

Trabecular bone score and insulin resistance in type 2 diabetes mellitus

2020 ◽  
Author(s):  
Ponce Maria Hayon ◽  
Laguna Mª del Carmen Serrano ◽  
Perez Maria Dolores Aviles ◽  
Beatriz Garcia Fontana ◽  
Sheila Gonzalez Salvatierra ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Trabecular Bone ◽  
Trabecular Bone Score
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