scholarly journals Retraction: Nitric Oxide Mediates Relative Airway Hyporesponsiveness to Lipopolysaccharide in Surfactant Protein A–Deficient Mice

2016 ◽  
Vol 55 (5) ◽  
pp. 758-758
2011 ◽  
Vol 44 (2) ◽  
pp. 175-184 ◽  
Author(s):  
Amy M. Pastva ◽  
Julia K. L. Walker ◽  
Lee A. Maddox ◽  
Sambuddho Mukherjee ◽  
Charles Giamberardino ◽  
...  

2001 ◽  
Vol 183 (6) ◽  
pp. 943-952 ◽  
Author(s):  
Michael J. Linke ◽  
Christopher E. Harris ◽  
Thomas R. Korfhagen ◽  
Francis X. McCormack ◽  
Alan D. Ashbaugh ◽  
...  

1999 ◽  
Vol 20 (2) ◽  
pp. 279-286 ◽  
Author(s):  
Ann Marie LeVine ◽  
Kim E. Kurak ◽  
Jo Rae Wright ◽  
Wendy T. Watford ◽  
Michael D. Bruno ◽  
...  

1998 ◽  
Vol 19 (4) ◽  
pp. 700-708 ◽  
Author(s):  
Ann Marie LeVine ◽  
Kim E. Kurak ◽  
Michael D. Bruno ◽  
James M. Stark ◽  
Jeffrey A. Whitsett ◽  
...  

Author(s):  
Philip O’Reilly ◽  
Judy M. Hickman-Davis ◽  
Philip McArdle ◽  
K. Randall Young ◽  
Sadis Matalon

2006 ◽  
Vol 55 (2) ◽  
pp. 143-147 ◽  
Author(s):  
Michael Linke ◽  
Alan Ashbaugh ◽  
Judith Koch ◽  
Reiko Tanaka ◽  
Peter Walzer

Following withdrawal of immunosuppression, surfactant protein A (SP-A)-deficient and wild-type mice cleared Pneumocystis murina infection in a similar manner, but exhibited significant differences in lymphocyte populations, interleukin (IL)-6 levels and chemokine expression levels. A higher percentage of lymphocytes were detected in lung lavage fluid from SP-A-deficient mice, but more CD4+ T cells were isolated from lung tissue of wild-type mice. Higher concentrations of IL-6 were detected in lavage fluid and enhanced expression of lymphotactin and RANTES were detected in the lungs of wild-type mice. Equal levels of surfactant protein D were detected in SP-A-deficient and wild-type mice and no differences were detected in markers of lung injury between the two strains of mice. Thus, SP-A does not enhance organism clearance, but does modulate the host immune response during resolution of P. murina infection.


Sign in / Sign up

Export Citation Format

Share Document