Single Walled Carbon Nanotube-Based Electrical Biosensor for the Label-Free Detection of Pathogenic Bacteria

2016 ◽  
Vol 16 (6) ◽  
pp. 6520-6525 ◽  
Author(s):  
Seung Min Yoo ◽  
Youn-Kyoung Baek ◽  
Sun Hae Ra Shin ◽  
Ju-Hyun Kim ◽  
Hee-Tae Jung ◽  
...  
2014 ◽  
Vol 2 (43) ◽  
pp. 7534-7543 ◽  
Author(s):  
Thomas J. Ondera ◽  
Ashton T. Hamme II

Antibody conjugated gold nanopopcorn attached SWCNT hybrid nanomaterials possess great potential for selective label-free detection and photothermal killing of bacteria.


2011 ◽  
Vol 98 (1) ◽  
pp. 013701 ◽  
Author(s):  
Rajesh ◽  
Basanta K. Das ◽  
Sira Srinives ◽  
Ashok Mulchandani

2006 ◽  
Vol 6 (11) ◽  
pp. 3499-3502 ◽  
Author(s):  
Dong-Won Park ◽  
Yo-Han Kim ◽  
Beom Soo Kim ◽  
Hye-Mi So ◽  
Keehoon Won ◽  
...  

We have developed a biosensor capable of detecting carcinoembryonic antigen (CEA) markers using single-walled carbon nanotube field effect transistors (SWNT-FETs). These SWNT-FETs were fabricated using nanotubes produced by a patterned catalyst growth technique, where the top contact electrodes were generated using conventional photolithography. For biosensor applications, SU-8 negative photoresist patterns were used as an insulation layer. CEA antibodies were employed as recognition elements to specific tumor markers, and were successfully immobilized on the sides of a single-walled carbon nanotube using CDI-Tween 20 linking molecules. The binding of tumor markers to these antibody-functionalized SWNT-FETs was then monitored continuously during exposure to dilute CEA solutions. The observed sharp decrease in conductance demonstrates the possibility of realizing highly sensitive, label-free SWNT-FET-based tumor sensors.


2014 ◽  
Vol 5 ◽  
pp. 2081-2091 ◽  
Author(s):  
Hari Krishna Salila Vijayalal Mohan ◽  
Jianing An ◽  
Yani Zhang ◽  
Chee How Wong ◽  
Lianxi Zheng

A single-walled carbon nanotube (SWCNT) in a field-effect transistor (FET) configuration provides an ideal electronic path for label-free detection of nucleic acid hybridization. The simultaneous influence of more than one response mechanism in hybridization detection causes a variation in electrical parameters such as conductance, transconductance, threshold voltage and hysteresis gap. The channel length (L) dependence of each of these parameters necessitates the need to include them when interpreting the effect of L on the response to hybridization. Using the definitions of intrinsic effective mobility (µe) and device field-effect mobility (µf), two new parameters were defined to interpret the effect of L on the FET response to hybridization. Our results indicate that FETs with ≈300 µm long SWCNT exhibited the most appreciable response to hybridization, which complied with the variation trend in response to the newly defined parameters.


Sign in / Sign up

Export Citation Format

Share Document