scholarly journals A gold nanopopcorn attached single-walled carbon nanotube hybrid for rapid detection and killing of bacteria

2014 ◽  
Vol 2 (43) ◽  
pp. 7534-7543 ◽  
Author(s):  
Thomas J. Ondera ◽  
Ashton T. Hamme II

Antibody conjugated gold nanopopcorn attached SWCNT hybrid nanomaterials possess great potential for selective label-free detection and photothermal killing of bacteria.

2016 ◽  
Vol 16 (6) ◽  
pp. 6520-6525 ◽  
Author(s):  
Seung Min Yoo ◽  
Youn-Kyoung Baek ◽  
Sun Hae Ra Shin ◽  
Ju-Hyun Kim ◽  
Hee-Tae Jung ◽  
...  

2011 ◽  
Vol 98 (1) ◽  
pp. 013701 ◽  
Author(s):  
Rajesh ◽  
Basanta K. Das ◽  
Sira Srinives ◽  
Ashok Mulchandani

2018 ◽  
Vol 101 (5) ◽  
pp. 1558-1565 ◽  
Author(s):  
Abdus Sobhan ◽  
Jun-Hyun Oh ◽  
Mi-Kyung Park ◽  
Jinyoung Lee

Abstract Background: The peanut protein Arachis hypogaea (Ara h) 6 is one of the most serious food allergens that contributes to food-related, life-threatening problems worldwide. The extremely low allergic dose demands for more selective and rapid methods for detecting Ara h 6. Objective: The goal of this study was to develop a single-walled carbon nanotube (SWCNT)-based biosensor for the rapid detection of Ara h 6 in commercial food products. Methods: The detection principle of this biosensor was based on the binding of Ara h 6 to the anti-Ara h 6 antibody (pAb) through 1-pyrenibutanoic acid succinimidyl ester. The resistance difference (ΔR) was calculated via linear sweep voltammetry using a potentiostat. Results: The ΔR increased as the Ara h 6 concentrations increased above the range of 100–107 pg/L. A specificity analysis showed that the anti-Ara h 6 pAb selectively interacted with Ara h 6 molecules in the buffer solution (pH 7.4). Conclusions: This research proposes that an SWCNT-based biosensor in self-assembly with antibodies could be an effective tool for the rapid detection of allergen proteins in food. Highlights: The developed biosensor exhibited higher sensitivity and selectivity. Application studies resulted in precise Ara h 6 detection in peanut-containing processed food.


2006 ◽  
Vol 6 (11) ◽  
pp. 3499-3502 ◽  
Author(s):  
Dong-Won Park ◽  
Yo-Han Kim ◽  
Beom Soo Kim ◽  
Hye-Mi So ◽  
Keehoon Won ◽  
...  

We have developed a biosensor capable of detecting carcinoembryonic antigen (CEA) markers using single-walled carbon nanotube field effect transistors (SWNT-FETs). These SWNT-FETs were fabricated using nanotubes produced by a patterned catalyst growth technique, where the top contact electrodes were generated using conventional photolithography. For biosensor applications, SU-8 negative photoresist patterns were used as an insulation layer. CEA antibodies were employed as recognition elements to specific tumor markers, and were successfully immobilized on the sides of a single-walled carbon nanotube using CDI-Tween 20 linking molecules. The binding of tumor markers to these antibody-functionalized SWNT-FETs was then monitored continuously during exposure to dilute CEA solutions. The observed sharp decrease in conductance demonstrates the possibility of realizing highly sensitive, label-free SWNT-FET-based tumor sensors.


2014 ◽  
Vol 5 ◽  
pp. 2081-2091 ◽  
Author(s):  
Hari Krishna Salila Vijayalal Mohan ◽  
Jianing An ◽  
Yani Zhang ◽  
Chee How Wong ◽  
Lianxi Zheng

A single-walled carbon nanotube (SWCNT) in a field-effect transistor (FET) configuration provides an ideal electronic path for label-free detection of nucleic acid hybridization. The simultaneous influence of more than one response mechanism in hybridization detection causes a variation in electrical parameters such as conductance, transconductance, threshold voltage and hysteresis gap. The channel length (L) dependence of each of these parameters necessitates the need to include them when interpreting the effect of L on the response to hybridization. Using the definitions of intrinsic effective mobility (µe) and device field-effect mobility (µf), two new parameters were defined to interpret the effect of L on the FET response to hybridization. Our results indicate that FETs with ≈300 µm long SWCNT exhibited the most appreciable response to hybridization, which complied with the variation trend in response to the newly defined parameters.


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