Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and beta cell glucokinase genes. Genetic reconstitution of diabetes as a polygenic disease.

Double Knockout ◽

Insulin Receptor Substrate-1 gene polymorphism and cardiovascular risk in non-insulin dependent diabetes mellitus

Blood Coagulation & Fibrinolysis ◽

10.1097/00001721-199509000-00026 ◽

1995 ◽

Vol 6 (6) ◽

pp. 594

Author(s):

P. J. Grant ◽

M. W. Mansfield ◽

M. H. Stickland.

Keyword(s):

Diabetes Mellitus ◽

Cardiovascular Risk ◽

Gene Polymorphism ◽

Insulin Receptor ◽

Molecular Scanning of the Glycogen Synthase and Insulin Receptor Substrate-1 Genes in Japanese Subjects with Non-Insulin-Dependent Diabetes Mellitus

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.1994.1951 ◽

1994 ◽

Vol 202 (1) ◽

pp. 463-469 ◽

Cited By ~ 26

Author(s):

K. Shimokawa ◽

H. Kadowaki ◽

H. Sakura ◽

S. Otabe ◽

R. Hagura ◽

...

Keyword(s):

Diabetes Mellitus ◽

Insulin Receptor ◽

Glycogen Synthase ◽

Insulin Dependent ◽

Japanese Subjects

Insulin receptor substrate-1 gene polymorphism and cardiovascular risk in non-insulin dependent diabetes mellitus and patients undergoing coronary angiography

Clinical & Laboratory Haematology ◽

10.1046/j.1365-2257.1997.00057.x ◽

1997 ◽

Vol 19 (2) ◽

pp. 123-128 ◽

Cited By ~ 7

Author(s):

N. OSSEI-GERNING ◽

M.W. MANSFIELD ◽

M.H. STICKLAND ◽

P.J. GRANT

Keyword(s):

Diabetes Mellitus ◽

Cardiovascular Risk ◽

Coronary Angiography ◽

Gene Polymorphism ◽

Insulin Receptor ◽

Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus

The Lancet ◽

10.1016/0140-6736(93)92694-o ◽

1993 ◽

Vol 342 (8875) ◽

pp. 828-832 ◽

Cited By ~ 205

Author(s):

K. Almind ◽

C. Bjørbaek ◽

H. Vestergaard ◽

T. Hansen ◽

S. Echwald ◽

...

Keyword(s):

Diabetes Mellitus ◽

Insulin Receptor ◽

Human Insulin Receptor Substrate-1: Variant Sequences in Familial Non-insulin-dependent Diabetes Mellitus

Diabetic Medicine ◽

10.1002/(sici)1096-9136(199602)13:2<133::aid-dia7>3.0.co;2-2 ◽

1996 ◽

Vol 13 (2) ◽

pp. 133-138 ◽

Cited By ~ 22

Author(s):

M. Armstrong ◽

F. Haldane ◽

R.W. Taylor ◽

K.G.M.M. Alberti ◽

D.M. Turnbull ◽

...

Keyword(s):

Diabetes Mellitus ◽

Insulin Receptor ◽

Human Insulin ◽

Human Insulin Receptor ◽

Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.94.8.4171 ◽

1997 ◽

Vol 94 (8) ◽

pp. 4171-4175 ◽

Cited By ~ 188

Author(s):

C. M. Rondinone ◽

L.-M. Wang ◽

P. Lonnroth ◽

C. Wesslau ◽

J. H. Pierce ◽

...

Keyword(s):

Diabetes Mellitus ◽

Insulin Receptor ◽

Phosphatidylinositol 3 Kinase ◽

Insulin Dependent ◽

Docking Protein ◽

Phosphatidylinositol 3

Autoimmunity to insulin, beta cell dysfunction, and development of insulin-dependent diabetes mellitus

Diabetes ◽

10.2337/diabetes.35.2.139 ◽

1986 ◽

Vol 35 (2) ◽

pp. 139-142 ◽

Cited By ~ 32

Author(s):

S. Srikanta ◽

A. T. Ricker ◽

D. K. McCulloch ◽

J. S. Soeldner ◽

G. S. Eisenbarth ◽

...

Keyword(s):

Diabetes Mellitus ◽

Beta Cell ◽

Beta Cell Dysfunction ◽

Cell Dysfunction ◽

Platelet insulin receptor determination in non-insulin dependent diabetes mellitus

Cellular and Molecular Life Sciences ◽

10.1007/bf02004539 ◽

1985 ◽

Vol 41 (3) ◽

pp. 422-423 ◽

Cited By ~ 27

Author(s):

M. Udvardy ◽

G. Pfliegler ◽

K. Rak

Keyword(s):

Diabetes Mellitus ◽

Insulin Receptor ◽

Does Beta Cell Death Result Exclusively from Genetically-Mediated Autoimmune Mechanisms? A Polemic — The Case for Environmental Factors in the Etiology of Insulin-dependent Diabetes Mellitus

Standardization of Epidemiologic Studies of Host Susceptibility ◽

10.1007/978-1-4899-1213-8_20 ◽

1994 ◽

pp. 145-164

Author(s):

Allan L. Drash

Keyword(s):

Diabetes Mellitus ◽

Cell Death ◽

Environmental Factors ◽

Beta Cell ◽

Beta Cell Death ◽

The Val985Met Insulin-Receptor Variant in the Danish Caucasian Population: Lack of Associations with Non—Insulin-Dependent Diabetes Mellitus or Insulin Resistance

The American Journal of Human Genetics ◽

10.1086/515464 ◽

1997 ◽

Vol 60 (6) ◽

pp. 1532-1535 ◽

Cited By ~ 11

Author(s):

Lars Hansen ◽

Torben Hansen ◽

Jesper O. Clausen ◽

Søren M. Echwald ◽

Søren A. Urhammer ◽

...

Keyword(s):

Diabetes Mellitus ◽

Insulin Resistance ◽

Insulin Receptor ◽

Caucasian Population ◽