scholarly journals Acquired resistance to Borrelia burgdorferi infection in the rabbit. Comparison between outer surface protein A vaccine- and infection-derived immunity.

1997 ◽  
Vol 99 (8) ◽  
pp. 2030-2035 ◽  
Author(s):  
D M Foley ◽  
Y P Wang ◽  
X Y Wu ◽  
D R Blanco ◽  
M A Lovett ◽  
...  
Keyword(s):  
Borrelia Burgdorferi ◽  
Outer Surface ◽  
Acquired Resistance ◽  
Protein A ◽  
Surface Protein ◽  
Outer Surface Protein A ◽  
Outer Surface Protein

Multiple cross-reactive seif-ligands for Borrelia burgdorferi outer surface protein A (OspA)-specific HLA-DR4-restricted T Cells

1999 ◽  
Vol 289 (5-7) ◽  
pp. 673 ◽  
Author(s):  
Bert Maier ◽  
Marc Molinger ◽  
Andrew P. Cope ◽  
Lars Fugger ◽  
Jens Schneider-Mergener ◽  
...  
Keyword(s):  
T Cells ◽  
Borrelia Burgdorferi ◽  
Outer Surface ◽  
Protein A ◽  
Surface Protein ◽  
Outer Surface Protein A ◽  
Outer Surface Protein ◽  
Multiple Cross

Immunogenicity of a recombinant Borrelia burgdorferi outer surface protein A vaccine against Lyme disease in children

1999 ◽  
Vol 135 (5) ◽  
pp. 575-579 ◽  
Author(s):  
Henry M. Feder ◽  
Jeri Beran ◽  
Christian Van Hoecke ◽  
Betsy Abraham ◽  
Norbert De Clercq ◽  
...  
Keyword(s):  
Lyme Disease ◽  
Borrelia Burgdorferi ◽  
Outer Surface ◽  
Protein A ◽  
Surface Protein ◽  
Outer Surface Protein A ◽  
Outer Surface Protein

scholarly journals Evidence for Vaccine Synergy between Borrelia burgdorferi Decorin Binding Protein A and Outer Surface Protein A in the Mouse Model of Lyme Borreliosis

2000 ◽  
Vol 68 (11) ◽  
pp. 6457-6460 ◽  
Author(s):  
Mark S. Hanson ◽  
Nita K. Patel ◽  
David R. Cassatt ◽  
Nancy D. Ulbrandt
Keyword(s):  
Borrelia Burgdorferi ◽  
Outer Surface ◽  
Binding Protein ◽  
Protein A ◽  
Surface Protein ◽  
Outer Surface Protein A ◽  
Outer Surface Protein ◽  
Antigen Vaccine ◽  
Single Antigen

ABSTRACT Mice immunized with either the predominantly vector-stage lipoprotein outer surface protein A (OspA) or the in vivo-expressed lipoprotein decorin binding protein A (DbpA) are protected againstBorrelia burgdorferi challenge. DbpA-OspA combinations protected against 100-fold-higher challenge doses than did either single-antigen vaccine and conferred significant protection against heterologous B. burgdorferi, B. garinii, andB. afzelii isolates, suggesting that there is synergy between these two immunogens.

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