A Day Hospital for Adults With Intellectual Disabilities and Psychiatric Disorders

2005 ◽  
Vol 56 (5) ◽  
pp. 609-609 ◽  
Author(s):  
G. Galli Carminati ◽  
Fabienne Gerber ◽  
Nadine Constantin
Keyword(s):  
Intellectual Disabilities ◽  
Psychiatric Disorders ◽  
Day Hospital ◽  
Adults With Intellectual Disabilities

scholarly journals Association between epilepsy and psychiatric disorders in adults with intellectual disabilities: systematic review and meta-analysis

BJPsych Open ◽  
2021 ◽  
Vol 7 (3) ◽  
Author(s):  
Basma Akrout Brizard ◽  
Bharati Limbu ◽  
Carolina Baeza-Velasco ◽  
Shoumitro Deb
Keyword(s):  
Systematic Review ◽  
Intellectual Disabilities ◽  
Psychiatric Disorders ◽  
Depressive Disorders ◽  
Psychotic Disorders ◽  
Meta Analysis ◽  
Risk Of Bias ◽  
Control Group ◽  
Pool Data ◽  
Adults With Intellectual Disabilities

Background Psychiatric disorders, such as depression and anxiety, are commonly associated with epilepsy in the general population, but the relationship between psychiatric disorders and epilepsy among adults with intellectual disabilities is unclear. Aims To conduct a systematic review and meta-analysis to assess whether epilepsy is associated with an increased rate of psychiatric disorders in adults with intellectual disabilities. Method We included literature published between 1985 and 2020 from four databases, and hand-searched six relevant journals. We assessed risk of bias by using SIGN 50 and the Cochrane risk of bias tool. Several meta-analyses were carried out. Results We included 29 papers involving data on 9594 adults with intellectual disabilities, 3180 of whom had epilepsy and 6414 did not. Of the 11 controlled studies that compared the overall rate of psychiatric disorders between the epilepsy and non-epilepsy groups, seven did not show any significant inter-group difference. Meta-analysis was possible on pooled data from seven controlled studies, which did not show any significant inter-group difference in the overall rate of psychiatric disorders. The rates of psychotic disorders, depressive disorders and anxiety disorders were significantly higher in the non-epilepsy control groups compared with the epilepsy group, with effect sizes of 0.29, 0.47 and 0.58, respectively. Epilepsy-related factors did not show any definite association with psychiatric disorders. Conclusions It is difficult to pool data from such heterogeneous studies and draw any definitive conclusion because most studies lacked an appropriately matched control group, which will be required for future studies.

scholarly journals Neurodevelopmental risk copy number variants in adults with intellectual disabilities and comorbid psychiatric disorders

2018 ◽  
Vol 212 (5) ◽  
pp. 287-294 ◽  
Author(s):  
Johan H. Thygesen ◽  
Kate Wolfe ◽  
Andrew McQuillin ◽  
Marina Viñas-Jornet ◽  
Neus Baena ◽  
...  
Keyword(s):  
Intellectual Disability ◽  
Intellectual Disabilities ◽  
Psychiatric Disorders ◽  
Copy Number ◽  
Copy Number Variants ◽  
Autism Spectrum ◽  
Comorbid Psychiatric Disorders ◽  
Pathogenic Cnvs ◽  
Adults With Intellectual Disabilities ◽  
Individuals With Intellectual Disabilities

BackgroundCopy number variants (CNVs) are established risk factors for neurodevelopmental disorders. To date the study of CNVs in psychiatric illness has focused on single disorder populations. The role of CNVs in individuals with intellectual disabilities and psychiatric comorbidities are less well characterised.AimsTo determine the type and frequency of CNVs in adults with intellectual disabilities and comorbid psychiatric disorders.MethodA chromosomal microarray analysis of 599 adults recruited from intellectual disabilities psychiatry services at three European sites.ResultsThe yield of pathogenic CNVs was high – 13%. Focusing on established neurodevelopmental disorder risk loci we find a significantly higher frequency in individuals with intellectual disabilities and comorbid psychiatric disorder (10%) compared with healthy controls (1.2%, P<0.0001), schizophrenia (3.1%, P<0.0001) and intellectual disability/autism spectrum disorder (6.5%, P < 0.00084) populations.ConclusionsIn the largest sample of adults with intellectual disabilities and comorbid psychiatric disorders to date, we find a high rate of pathogenic CNVs. This has clinical implications for the use of genetic investigations in intellectual disability psychiatry.Declaration of interestNone.

Aging in Adults With Intellectual Disabilities

2014 ◽  
Vol 19 (1) ◽  
pp. 36-43
Author(s):  
Tracy Lazenby-Paterson ◽  
Hannah Crawford
Keyword(s):  
Intellectual Disabilities ◽  
Swallowing Disorders ◽  
Speech And Language ◽  
Adults With Intellectual Disabilities

The literature recognizes the important role of the Speech and Language Pathologist (SLP) in the treatment of communication and swallowing disorders in children with Intellectual Disabilities (ID). However there is also a need to emphasize the importance of specialist SLP input across the lifespan of people with ID, and to recognize the specific, ongoing and changing communication and swallowing needs of adults with ID as they get older.

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