In-Hospital and Long-Term Prognostic Value of Fibrinogen, CRP, and IL-6 Levels in Patients with Acute Myocardial Infarction Treated with Thrombolysis

Angiology ◽  
2006 ◽  
Vol 57 (3) ◽  
pp. 283-293 ◽  
Author(s):  
A. Ziakas ◽  
S. Gavrilidis ◽  
G. Giannoglou ◽  
E. Souliou ◽  
K. Gemitzis ◽  
...  
2012 ◽  
Vol 18 (6) ◽  
pp. 480-486 ◽  
Author(s):  
Akira Sato ◽  
Michiaki Hiroe ◽  
Daiki Akiyama ◽  
Hiroyuki Hikita ◽  
Toshihiro Nozato ◽  
...  

2021 ◽  
Vol 19 ◽  
pp. 205873922110390
Author(s):  
Hyeon Jeong Kim ◽  
Jang Hoon Lee ◽  
Se Yong Jang ◽  
Myung Hwan Bae ◽  
Dong Heon Yang ◽  
...  

We developed and assessed whether a novel neutrophil-to-hemoglobin and lymphocyte (NHL) score would improve the ability to predict clinical outcome compared with neutrophil-to-lymphocyte ratio (NLR) and systemic immune-inflammation index (SII) in acute myocardial infarction (AMI). We examined 13,072 AMI patients from the Korean AMI Registry–National Institute of Health database. NHL score was calculated as follows: NHL score (U) = N/(Hb × L), where N, Hb, and L are baseline blood neutrophil, hemoglobin, and lymphocyte count. The primary outcome was the occurrence of major adverse cerebrocardiovascular events (MACCEs) at 2 years. The NLR, SII, and NHL score were independent predictors of 2-year MACCEs. The area under the curve of the NHL score (0.637) for predicting 2-year MACCEs was significantly higher compared with those of SII (0.589) and NLR (0.607). The NHL score significantly improved the reclassification and integrated discrimination compared with NLR ( p < 0.0001) and SII ( p < 0.0001). A high NHL score (≥ 0.35 U) was an independent predictor of 2-year MACCEs (adjusted hazard ratio, 1.41; 95% confidence interval, 1.29–1.55; p < 0.001). The NHL score could be a novel model for predicting long-term MACCEs in patients with AMI.


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