scholarly journals Is Coronary Artery Ectasia a Thrombotic Disease?

Angiology ◽  
2018 ◽  
Vol 70 (1) ◽  
pp. 62-68 ◽  
Author(s):  
Siwen Liang ◽  
Yue Zhang ◽  
Xiangyu Gao ◽  
Huiqiang Zhao ◽  
Beibing Di ◽  
...  

Coronary artery ectasia (CAE) is a rare disease and a substantial portion of patients with CAE are first diagnosed with acute myocardial infarction (AMI). The question was raised if CAE was a kind of thrombotic disease. We assessed a consecutive series of 119 patients with CAE including 32 patients with AMI (CAE + AMI group) and 87 patients without AMI (CAE group). During the same period, 90 patients with coronary heart disease, 90 patients with normal coronary arteries (control), and 120 AMI patients without CAE (AMI group) were randomly selected and evaluated. Both current and previous AMI prevalence rates in the CAE population were higher than the AMI rate for the other patients undergoing coronary angiograms; the mean platelet volume and fibrinogen were increased in the CAE + AMI and CAE groups. For patients with CAE with AMI, most of the thrombotic lesions were in the ectasia site. After dividing the patients with CAE into with and without antiplatelet treatment groups before admission, the AMI rate was lower in the antiplatelet group. Platelets may participate in the thrombotic process in CAE. Antiplatelet treatment may decrease the AMI rate of patients with CAE.

2018 ◽  
Vol 53 (4) ◽  
pp. 269 ◽  
Author(s):  
Reza Heidary Moghadam ◽  
Afshar Shahmohammadi ◽  
Nader Asgari ◽  
Koorosh Azizi ◽  
Sahar Mehr Mansour ◽  
...  

2013 ◽  
Vol 35 (3) ◽  
pp. 202-205
Author(s):  
Nasir Sivri ◽  
Tulin Yalta ◽  
Kenan Yalta ◽  
Armagan Altun ◽  
Necdet Sut ◽  
...  

2019 ◽  
Vol 70 (4) ◽  
pp. 1242-1244
Author(s):  
Maria-Cristina Apavaloaie (Vladeanu) ◽  
Iris Bararu Bojan ◽  
Oana Viola Badulescu ◽  
Carmen Elena Plesoianu ◽  
Daniela Jitaru ◽  
...  

Atherosclerosis and platelet activity are two important chain factors linked together in the onset and the severity of coronary artery disease. Our study included 60 diabetic patients with ischemic heart disease, all having underwent coronary angiography. In this substudy from a larger epigenetical and genetical study, we phocused on the interrelationship between vessel disease and primary hemostasis. The haematological parameters included were platelet count (PLT), the platelet distribution width (PDW), the mean platelet volume (MPV) and the platelet larger cell ratio (P-LCR). ). The severity of the coronary disease was defined by the number of stenotic/occluded coronary arteries. We demonstrated a positive corelation with the duration of diabetes (p=0.032), as 34% of the patients with a long duration of the diabetes had a higher number of platelets. The mean platelet volume was slightly elevated in diabetic females over 65 years old, compared to younger diabetic men, though not statistically significant (p=0.101). Although the investigated parameters were mostly in the normal range, the fact that for some cathegories of patients they were orientated towards the upper limit, raises some questions for the next studies. Future adjustments of lot number and selection criteria for the following studies are needed. Using the MPV as a prediction test for cardiovascular complications is still a controversial subject, since the scientifical background contains both positive and negative studies on this matter.


2013 ◽  
Vol 3 ◽  
pp. 241-245 ◽  
Author(s):  
Serafettin Demir ◽  
Mustafa Kemal Avsar ◽  
Zeynep Karakaya ◽  
Murat Selcuk ◽  
Aydın Rodi Tosu ◽  
...  

2007 ◽  
Vol 24 (2) ◽  
pp. 99-103 ◽  
Author(s):  
Atila Bitigen ◽  
Ali Cevat Tanalp ◽  
Orhan Hakan Elonu ◽  
Yusuf Karavelioglu ◽  
Nihal Ozdemir

2011 ◽  
Vol 18 (4) ◽  
pp. 387-392 ◽  
Author(s):  
Ercan Varol ◽  
Bayram Ali Uysal ◽  
Abdullah Dogan ◽  
Mehmet Ozaydin ◽  
Dogan Erdogan

Author(s):  
Pradeep Nambiar ◽  
Chandermohan Mittal

Objective Harvesting of the right internal thoracic artery (RITA) under direct vision, through a left minithoracotomy, without robotic or thoracoscopic assistance has never been done or described before. Bilateral internal thoracic arteries (BITAs) in coronary artery bypass grafting (CABG) have shown greater survival and freedom from reintervention. The aim was to develop a multivessel minimally invasive CABG technique in which the BITAs are harvested under direct vision and complete revascularization of the myocardium is done by the off-pump method, using only BITAs (left internal thoracic artery [LITA]–RITAY) through a 2-in left minithoracotomy, without robotic/thoracoscopic assistance—the “Nambiar Technique.” Methods From August 2011 to December 2012, a total of 150 patients underwent off-pump minimally invasive multivessel CABG using BITAs, through a 2-in left minithoracotomy incision. Both internal thoracic arteries were harvested directly under vision, and complete revascularization of the myocardium was done using the LITA-RITAY composite conduit, followed by flow study of the grafts. Coronary artery stabilization for anastomoses was done by using epicardial stabilizers introduced through the minithoracotomy. Results One hundred fifty patients had minimally invasive total arterial myocardial revascularization using BITAs (LITA-RITA Y composite conduit) via a left minithoracotomy. The mean number of grafts was 2.8. A total of 81.6% of the patients had three grafts. Ejection fraction was 34.5 ± 5.2. There was one mortality but no major morbidity. The RITA and LITA harvest times were 39.5 ± 11.2 and 35.2 ± 8.6 minutes, respectively. The total time in the operating room (including extubation) was 331.5 ± 42.5 minutes, and operating time was 240.8 ± 24.6 minutes. One hundred twenty-six patients (87.7%) were extubated on the table. The mean hospital stay was 3.1 days. One patient (0.6%) had an elective conversion to sternotomy because the flow in the LITA-RITA Y composite conduit was inadequate and had saphenous vein grafts. Coronary angiograms were done in 37 patients (25%); and computed tomographic angiograms, in 33 patients (22%), and the grafts were patent. Stress test was done in 80 patients (53%), which had normal findings. Conclusions The Nambiar Technique encompassed using a 2-in left minithoracotomy incision through which the BITAs were conveniently harvested in a skeletonized manner under direct vision without robotic or thoracoscopic assistance. Multivessel total arterial revascularization was then done using the LITA-RITA Y composite conduit by the off-pump methodology. The early outcomes have been excellent, and coronary angiograms showed widely patent grafts. This technique is reproducible and can be done on an empty beating heart to aid in training.


Sign in / Sign up

Export Citation Format

Share Document