scholarly journals Massive Lymphoid Hyperplasia Presenting with Obstructive Sleep Apnea Secondary to Lingual and Palatine Tonsil Hyperplasia

2011 ◽  
Vol 90 (4) ◽  
pp. E36-E38 ◽  
Author(s):  
Gül Özbilen Acar ◽  
Murat Yener ◽  
Harun Cansiz ◽  
Engin Acioğlu ◽  
Nukhet Tuziner
2017 ◽  
Vol 128 (4) ◽  
pp. 1002-1006 ◽  
Author(s):  
Sebastian M. Jara ◽  
Edward M. Weaver

2014 ◽  
Vol 271 (8) ◽  
pp. 2305-2310 ◽  
Author(s):  
Chi-Chih Lai ◽  
Michael Friedman ◽  
Hsin-Ching Lin ◽  
Pa-Chun Wang ◽  
Cheng-Ming Hsu ◽  
...  

2016 ◽  
Vol 8 (3) ◽  
pp. E229-E231 ◽  
Author(s):  
Lijuan Song ◽  
Yingshen Lu ◽  
Wenjin Liao ◽  
Nanshan Zhong ◽  
Jianxing He ◽  
...  

2019 ◽  
Vol 162 (2) ◽  
pp. 230-233
Author(s):  
Abeer Al Ali ◽  
Emilie Bois ◽  
Imene Boujemla ◽  
Natacha Teissier ◽  
Thierry Van den Abbeele ◽  
...  

Our objective was to assess whether adenotonsillotomy improved pharyngeal compliance, which is a risk factor for sleep-disordered breathing. Otherwise healthy children underwent Obstructive Sleep Apnea (OSA)-18 questionnaire and a pre- and postoperative acoustic pharyngometry in both sitting and supine positions, allowing the measurement of the volume of the palatine tonsil region and pharyngeal compliance. Thirty-five children (median age 5.3 years) were enrolled; they were reevaluated at a median of 18 days (25th-75th percentiles, 15-25) after surgery. Participants were compared according to a normal (n = 18) or an increased (n = 17) preoperative pharyngeal compliance. Surgery was associated with a significant decrease in OSA-18 and Brodsky scores, with a median increase in palatine volume of 0.13 cm3 (25th-75th percentiles, 0.00-0.73). A decrease in pharyngeal compliance was observed in children with increased preoperative compliance. The variation of palatine volume after surgery was positively related to the variation of pharyngeal compliance, suggesting that obstruction relief was associated with muscle relaxation in children with normal preoperative compliance.


2020 ◽  
Vol 10 (3) ◽  
pp. 228-233
Author(s):  
Ayesha Mehwish ◽  
Ambreen Usmani

Sleep constitutes one-third of our life and a good sleep affects the physical, mental and behavioral aspects of an individual. Disturbance in the normal biological rhythm of an individual can disrupt one’s performance. Sleep disorders are many but the type that could take one’s life is obstructive sleep apnea. Therefore it is important to know the anatomy of involved structures that are responsible for the pathophysiology of the above-mentioned condition. Obstructive sleep apnea-OSA is evolving as a worldwide health epidemic and is confronting an increasing prevalence especially due to the obesity pandemic. Though extensive global prevalence facts and figures are still missing, and worldwide OSA research in standings of activity, value, and socio-economic features has not yet been revealed. Ultrasound of palatine tonsil is an emerging and novel technique, as it is noninvasive and safest modality that can be used to determine severity of OSA. High frequency ultrasound is an impeccable diagnostic tool for assessment of tonsils in children and adults. It is cost effective, portable, noninvasive, painless, quick and easily accessible as compare to CT and MRI imaging


2021 ◽  
Vol 12 ◽  
Author(s):  
Anna Carrasco ◽  
Isabella Sjölander ◽  
Aline Van Acker ◽  
Andy Dernstedt ◽  
Johan Fehrm ◽  
...  

Tonsil hyperplasia is the most common cause of pediatric obstructive sleep apnea (OSA). Despite the growing knowledge in tissue immunology of tonsils, the immunopathology driving tonsil hyperplasia and OSA remains unknown. Here we used multi-parametric flow cytometry to analyze the composition and phenotype of tonsillar innate lymphoid cells (ILCs), T cells, and B cells from pediatric patients with OSA, who had previous polysomnography. Unbiased clustering analysis was used to delineate and compare lymphocyte heterogeneity between two patient groups: children with small tonsils and moderate OSA (n = 6) or large tonsils and very severe OSA (n = 13). We detected disturbed ILC and B cell proportions in patients with large tonsils, characterized by an increase in the frequency of naïve CD27-CD21hi B cells and a relative reduction of ILCs. The enrichment of naïve B cells was not commensurate with elevated Ki67 expression, suggesting defective differentiation and/or migration rather than cellular proliferation to be the causative mechanism. Finally, yet importantly, we provide the flow cytometry data to be used as a resource for additional translational studies aimed at investigating the immunological mechanisms of pediatric tonsil hyperplasia and OSA.


2019 ◽  
Vol 4 (5) ◽  
pp. 878-892
Author(s):  
Joseph A. Napoli ◽  
Linda D. Vallino

Purpose The 2 most commonly used operations to treat velopharyngeal inadequacy (VPI) are superiorly based pharyngeal flap and sphincter pharyngoplasty, both of which may result in hyponasal speech and airway obstruction. The purpose of this article is to (a) describe the bilateral buccal flap revision palatoplasty (BBFRP) as an alternative technique to manage VPI while minimizing these risks and (b) conduct a systematic review of the evidence of BBFRP on speech and other clinical outcomes. A report comparing the speech of a child with hypernasality before and after BBFRP is presented. Method A review of databases was conducted for studies of buccal flaps to treat VPI. Using the principles of a systematic review, the articles were read, and data were abstracted for study characteristics that were developed a priori. With respect to the case report, speech and instrumental data from a child with repaired cleft lip and palate and hypernasal speech were collected and analyzed before and after surgery. Results Eight articles were included in the analysis. The results were positive, and the evidence is in favor of BBFRP in improving velopharyngeal function, while minimizing the risk of hyponasal speech and obstructive sleep apnea. Before surgery, the child's speech was characterized by moderate hypernasality, and after surgery, it was judged to be within normal limits. Conclusion Based on clinical experience and results from the systematic review, there is sufficient evidence that the buccal flap is effective in improving resonance and minimizing obstructive sleep apnea. We recommend BBFRP as another approach in selected patients to manage VPI. Supplemental Material https://doi.org/10.23641/asha.9919352


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