scholarly journals Cerebrospinal Fluid Rhinorrhea as the First Symptom of Metastatic Prostate Adenocarcinoma

2021 ◽  
pp. 014556132110167
Author(s):  
Magdalena Ostrowska ◽  
Maciej J. Wróbel
Keyword(s):  
Prostate Cancer ◽  
Cerebrospinal Fluid ◽  
Paranasal Sinuses ◽  
Cancer Metastasis ◽  
Treatment Strategies ◽  
Prostate Adenocarcinoma ◽  
Cerebrospinal Fluid Rhinorrhea ◽  
Csf Leakage ◽  
Prostate Cancer Metastasis ◽  
Csf Rhinorrhoea

The most common cause of cerebrospinal fluid (CSF) rhinorrhoea is damage to the skull base with a dura mater’s rupture due to an accident or an iatrogenic injury. This applies to over 96% of cases. Other possibilities that can lead to CSF leakage are neoplasms of the nasal cavity, paranasal sinuses, and nasopharynx. Although prostate cancer spreads to bones, cranial metastases to paranasal sinuses are extremely rare. We present a case of an 83-year-old patient with CSF leakage due to infiltrating metastatic prostate cancer. Cerebrospinal fluid rhinorrhea turned out to be the first symptom of prostate cancer metastasis. Diagnostic and treatment strategies are presented in the discussion.

scholarly journals Prostate Cancer Metastasis Causing Occipital Condyle Syndrome: A Rare Clinical Entity

2021 ◽  
Vol 8 (03) ◽  
pp. 5272-5274
Author(s):  
Nurlan İsayev ◽  
Levent Yücel ◽  
Hatice Seçil Akyıldız ◽  
Hazan Başak ◽  
Süha Beton ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Skull Base ◽  
Cancer Metastasis ◽  
Prostate Adenocarcinoma ◽  
Occipital Condyle ◽  
Rare Clinical Entity ◽  
Resonance Imaging ◽  
Case Presentation ◽  
Prostate Cancer Metastasis ◽  
The Right

Introduction: Prostate cancer metastasis to clivus and occipital condyle are extremely rare and only a few cases are published. We present a case with metastasis of prostate cancer to skull base causing occipital condyle syndrome (OCS). Case Presentation: A-56-year-old man was referred to our clinic with complaints of dysphagia for two months and headache on his right occipital region for five months. There was deviation of the tongue to the right side in his physical examination. He was performed surgery for prostate adenocarcinoma for 2 years ago. Magnetic resonance imaging and computed tomography showed a mass destructed to the clivus and right occipital condyle. Biopsy confirmed the prostate adenocarcinoma metastasis. The patient died after two months from diagnosis of skull base metastasis. Conclusion: Otolaryngologists and urologists should be aware for early diagnosis of OCS in a patient with prostate cancer. Early physical and radiological examination of the patients may improve the prognosis.

scholarly journals Metastatic Adenocarcinoma of Prostate posing as upper tract ureteral mass

2021 ◽  
Vol 5 (1) ◽  
pp. 98-101
Author(s):  
Anil Kumar Sah ◽  
Bipin Maharjan ◽  
Mahesh Bahadur Adhikari ◽  
Reena Rana ◽  
Rajesh Panth ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Urothelial Carcinoma ◽  
Cancer Metastasis ◽  
Neuroendocrine Differentiation ◽  
Prostate Adenocarcinoma ◽  
Upper Tract Urothelial Carcinoma ◽  
Normal Prostate ◽  
Upper Tract ◽  
Carcinoma Prostate ◽  
Prostate Cancer Metastasis

Prostate cancer metastasis to the ureter is extremely rare because only 45 such cases have been reported worldwide in the last century. It accounts for 30% of ureteral metastasis. Neuroendocrine differentiation is approximately 1% of the entire primary prostate adenocarcinoma pathology. Metastatic prostate cancer may pose as upper tract urothelial carcinoma. Prostate may look normal on clinic-radiological examination in prostate cancer. Majority of such cases are managed with nephroureterectomy. Herein, we report a case of 62-year gentleman, who presented with refractory left flank pain with repeated imaging suggestive of neoplastic left ureteric stricture and normal prostate on clinic-radiological examinations. The case was later found with the diagnosis of metastatic prostate adenocarcinoma with neuroendocrine differentiation after left sided nephroureterectomy done for a provisional diagnosis of Upper Tract Urothelial Carcinoma (UTUC). 

The Use of Methylene Blue Staining Test in Determining the CSF Leaks Location of the Anterior Skull Base

2018 ◽  
Vol 69 (6) ◽  
pp. 1376-1377
Author(s):  
Razvan Hainarosie ◽  
Teodora Ghindea ◽  
Irina Gabriela Ionita ◽  
Mura Hainarosie ◽  
Cristian Dragos Stefanescu ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Cerebrospinal Fluid ◽  
Intrathecal Injection ◽  
Diagnostic Procedures ◽  
Blue Staining ◽  
Csf Leak ◽  
Glucose Content ◽  
Csf Rhinorrhea ◽  
Cerebrospinal Fluid Rhinorrhea ◽  
Csf Leakage

Cerebrospinal fluid rhinorrhea represents drainage of cerebrospinal fluid into the nasal cavity. The first steps in diagnosing CSF rhinorrhea are a thorough history and physical examination of the patient. Other diagnostic procedures are the double ring sign, glucose content of the nasal fluid, Beta-trace protein test or beta 2-transferrin. To establish the exact location of the defect imagistic examinations are necessary. However, the gold standard CSF leakage diagnostic method is an intrathecal injection of fluorescein with the endoscopic identification of the defect. In this paper we analyze a staining test, using Methylene Blue solution, to identify the CSF leak�s location.

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