scholarly journals Allergic Fungal Sinusitis with Intracranial Extension and Frontal Lobe Symptoms: A Case Report

1994 ◽  
Vol 73 (6) ◽  
pp. 402-404 ◽  
Author(s):  
William M. Lydiatt ◽  
Anne Sobba-Higley ◽  
James V. Huerter ◽  
Lyal G. Leibrock

This is the first report of AFS which caused frontal lobe symptomatology and which resolved with surgical therapy. The surgical approach used provided excellent exposure and the sinuses could be examined and thoroughly cleaned both from above and intranasally. The dural defect, which resulted from the destruction of the cribiform and fovea ethmoidalis, was easily reconstructed with a pericranial flap. This exposure facilitates debridement and reconstruction while minimizing complications such as cerebral spinal fluid leakage or brain injury which may occur with endoscopic manipulations in patients with bony destruction and loss of normal landmarks.

2011 ◽  
Vol 27 (4) ◽  
pp. e98-e100 ◽  
Author(s):  
Animesh Petkar ◽  
Luigi Rao ◽  
Daniel R. Elizondo ◽  
Jeffrey Cutler ◽  
Donald Taillon ◽  
...  

Orbit ◽  
2014 ◽  
Vol 33 (4) ◽  
pp. 311-313 ◽  
Author(s):  
Kristina Y. Pao ◽  
Vladimir Yakopson ◽  
Joseph C. Flanagan ◽  
Ralph C. Eagle

2005 ◽  
Vol 119 (11) ◽  
pp. 875-881 ◽  
Author(s):  
Neeraj Singh ◽  
N H Bhalodiya

Aim: To evaluate the criteria for diagnosing allergic fungal sinusitis and to maintain permanent drainage and ventilation, while preserving the integrity of mucosa. Methods: This is a prospective study of 251 patients with chronic rhinosinusitis with or without polyposis, of whom 199 were treated surgically. Mucus sample collection, nasal secretion culture, surgical specimen handling and histological evaluation of surgical specimens are described. The management included wide local endoscopic sinus debridement, adequate sinus aeration, post-operative use of steroids and antifungal therapy. Results: Fungal cultures of nasal secretions were positive in 201 (80.01 per cent) of 251 patients. Of the 199 surgical cases, fungal elements were found in 156 histological specimens (62.1 per cent). Allergic mucin was found in 182 patients (91.45 per cent). Nasal obstruction and proptosis were the commonest presentations. All pre-operative versus post-operative changes in AFS-associated complaints reached statistical significance of p < 0.001. The ethmoid sinus was commonly involved with adjacent lamina papyracea exhibiting demineralization in 26.6 per cent of cases. Intracranial extension was seen in 15 cases. Recurrence was noted in 11 cases. Conclusion: Comprehensive treatment with endoscopic sinus surgery, steroids and antifungal therapy is needed. AFS is readily recurrent. Long-term follow up is important.


2001 ◽  
Vol 104 (12) ◽  
pp. 1147-1150 ◽  
Author(s):  
Yoshinori Matsuwaki ◽  
Tsuneya Nakajima ◽  
Makoto Iida ◽  
Osamu Nohara ◽  
Shinniti Haruna ◽  
...  

2020 ◽  
Vol 77 ◽  
pp. 698-700
Author(s):  
Arwa A. Al Muslat ◽  
Basmah M. Alghmdi ◽  
Abdullah J. AlShehri ◽  
Rakan A. Alhaidey ◽  
M. Anas Dababo ◽  
...  

2020 ◽  
Vol 4 (4) ◽  
pp. 569-571
Author(s):  
Tyler Lopachin ◽  
Grace Landers

Introduction: Allergic fungal sinusitis (AFS) is a relatively uncommon cause of sinus pain and congestion. Extreme cases may require specialty evaluation and surgical treatment. Case Report: In this case, an otherwise healthy young man presented to the emergency department with sinus pain and congestion for two weeks and was admitted to surgery for resection of his AFS. Conclusion: This case demonstrates how a thorough history and physical exam can help catch potentially serious diseases, such as allergic fungal sinusitis, from the frequently benign chief complaint of sinus pain.


2014 ◽  
Vol 5 (3) ◽  
pp. ar.2014.5.0098 ◽  
Author(s):  
Martin Oman Evans ◽  
Christopher Albert Coop

A case report of recalcitrant allergic fungal sinusitis (AFS) refractory to systemic corticosteroids and multiple functional endoscopic sinus surgeries (FESSs) treated with anti-IgE antibody omalizumab is reported. AFS is often classified with chronic rhinosinusitis (CRS). Although similar symptoms are among the two diseases, AFS has a unique pathophysiology. Patients with AFS demonstrate type 1 hypersensitivity to fungal allergens, increased total serum IgE, increased CD8+ T-cell prevalence, and IL-4 and IL-5 response. Omalizumab should be considered in the treatment of AFS.


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