scholarly journals Investigation of neutrophil lymphocyte ratio and blood glucose regulation in patients with type 2 diabetes mellitus

2014 ◽  
Vol 42 (2) ◽  
pp. 581-588 ◽  
Author(s):  
Fatih Sefil ◽  
Kemal Turker Ulutas ◽  
Recep Dokuyucu ◽  
Ahmet Taner Sumbul ◽  
Erhan Yengil ◽  
...  
2020 ◽  
pp. 1-4
Author(s):  
V Sandeep Kumar ◽  
Aishwarya Ganga S N. ◽  
Anand A. S.

Introduction: Neutrophilic leukocytosis is directly associated with the pathogenesis of atherosclerosis in patients with diabetes mellitus (DM). Increased white blood cell (WBC) count is related to cardiovascular disease in patients with type 2 diabetes mellitus; raised neutrophil lymphocyte ratio (NLR) is associated with metabolic syndrome. concerning a correlation between glycosylated haemoglobin (HbA1c) and NLR. Aims and objectives: The aim of the present study was to investigate the neutrophils lymphocyte ratio (NLR) and blood glucose regulation in type 2 diabetes patients. Methods: This prospective study of 6 months duration was conducted in patients with type 2 diabetes mellitus, divided into two groups according to HbA1c levels. group 1- HbA1c levels ≤ 7%; group 2-HbA1c levels > 7%. WBC, neutrophil and lymphocyte counts were determined by automated analyser, HbA1C was calculated using Afinion 2.Results: Of total 50 patients included, Random blood glucose, neutrophil , WBC counts ,NLR, HbA1C were significantly higher in group 2 compared to group 1.Conclusion:NLR of uncontrolled group (HbA1c>7%)was significantly higher than that of controlled group(HbA1C<7%) .We conclude that NLR gives us very good and similar results to know the early complications of uncontrolled DM.


Author(s):  
Nurahmi Nurahmi ◽  
Budi Mulyono ◽  
Windarwati Windarwati

Progressivity of type 2 Diabetes Mellitus (DM) is associated with a condition of chronic inflammation. The Neutrophil-Lymphocyte Ratio (NLR) has become a potential new marker of inflammation to detect chronic inflammation. This research aimed to determine NLR differences between controlled type 2 DM and uncontrolled type 2 DM groups. This research conducted an observational with a cross-sectional approach to 56 patients with type 2 diabetes. The identity, anthropometric measurements, and laboratory data of routine blood exam and HbA1c were carried out on each research subject, and then the NLR calculations were performed. The subjects were 20 (35.70%) controlled type 2 DM patients, 36 (64.30%) uncontrolled type 2 DM patients, consisting of 36 (64.30%) male and 20 (35.70%) females. The NLR value was statistically significantly higher in uncontrolled type 2 DM patients than controlled type 2 DM patients, which was 1.90±0.84 compared to 1.52±0.50 (p=0.035). There was a significant difference in the NLR value between the uncontrolled type 2 DM group and the controlled type 2 DM group.


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