scholarly journals Sporadic multiple renal angiomyolipoma with lymph node involvement: a case report and literature review

2021 ◽  
Vol 49 (3) ◽  
pp. 030006052110017
Author(s):  
Xiaobo Ding ◽  
Meizi Cui ◽  
Tiejun Wang ◽  
Helei Wang ◽  
Xinyu Wang ◽  
...  
Keyword(s):  
Lymph Node ◽  
Tuberous Sclerosis ◽  
Partial Nephrectomy ◽  
Tuberous Sclerosis Complex ◽  
Radical Nephrectomy ◽  
Vena Cava ◽  
Clinical Manifestations ◽  
Lymph Node Involvement ◽  
Renal Angiomyolipoma ◽  
Node Involvement

Angiomyolipoma (AML) is a benign tumor that mainly occurs in the kidneys. Simultaneous involvement of the kidney and local regional lymph nodes is very rare and might be misdiagnosed as a metastasizing malignant cancer. In the present study, a 50-year-old woman was referred to our hospital after a routine health screening ultrasound. Sporadic multiple renal AML with lymph node involvement was suspected based on the clinical manifestations and radiologic features. Partial nephrectomy was performed and a para-inferior vena cava lymph node was removed. The pathologic results confirmed multiple AML with lymph node invasion. We also reviewed the English-language literature regarding renal AML with lymph node involvement. We found that middle-aged women were likely to develop this disease and that loin pain was the main presenting feature. Most patients had no history of tuberous sclerosis complex. Radical nephrectomy was the predominant treatment. No local recurrence or distant metastasis occurred in any patients after radical nephrectomy or partial nephrectomy. In conclusion, renal AML with lymph node involvement is rare but can occur in both patients with tuberous sclerosis complex and those with multiple sporadic AML. Partial nephrectomy should be the first-line treatment, after which further treatment is not necessary.

Renal Angiomyolipoma Associated with Lymph Node Involvement and Renal Cell Carcinoma in Patients with Tuberous Sclerosis

1989 ◽  
Vol 141 (4) ◽  
pp. 930-932 ◽  
Author(s):  
Robert S. Taylor ◽  
David B. Joseph ◽  
Edward C. Kohaut ◽  
Edward R. Wilson ◽  
Anton J. Bueschen
Keyword(s):  
Renal Cell Carcinoma ◽  
Lymph Node ◽  
Cell Carcinoma ◽  
Tuberous Sclerosis ◽  
Renal Cell ◽  
Lymph Node Involvement ◽  
Renal Angiomyolipoma ◽  
Node Involvement

Diagnostic accuracy of preoperative computed tomography used alone to detect lymph-node involvement at radical nephrectomy

2015 ◽  
Vol 49 (2) ◽  
pp. 142-148 ◽  
Author(s):  
Stephen S. Connolly ◽  
Aditya Raja ◽  
Helen Stunell ◽  
Deepak Parashar ◽  
Sara Upponi ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Lymph Node ◽  
Diagnostic Accuracy ◽  
Radical Nephrectomy ◽  
Lymph Node Involvement ◽  
Node Involvement

Renal Angiomyolipoma: Report of three cases with Regional Lymph Node Involvement and/or with Renal Cell Carcinoma

1995 ◽  
Vol 81 (6) ◽  
pp. 469-474 ◽  
Author(s):  
György Csanaky ◽  
Zoltán Szereday ◽  
Tamás Magyarlaki ◽  
Gábor Méhes ◽  
Tamás Herbert ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Tuberous Sclerosis ◽  
Malignant Transformation ◽  
Renal Cell ◽  
Dna Ploidy ◽  
Lymph Node Involvement ◽  
Node Involvement

Aims and background Angiomyolipomas (AMLs) are benign hamartoid tumors which frequently occur in tuberous sclerosis (TS). They may be manifest at different organ sites such as kidneys, lymph nodes, liver and lung and may be associated with renal cell carcinoma (RCC). The nature of multiple organ involvement in AML (metastasis versus multicentric synchronous tumors), the malignant transformation and the relation of AML to RCC have not been sufficiently clarified. Study design Three cases of renal AMLs in patients with tuberous sclerosis associated with lymphangioleiomyomatosis of the paraaortic lymph nodes and/or with RCC are reported. The concise clinical history of the patients as well as the findings of histology, immunohistochemistry and quantitative DNA analysis are presented. Results The multicentric form of AML and coincidence of renal AML and RCC were observed in 2 patients. AML and RCC were found within the same focus in one of the cases. RCCs were either aneuploid or “near diploid”, whereas one of the multicentric AMLs showed a discordant DNA ploidy pattern, namely aneuploidy in the kidney and diploidy in the lymph nodes. Conclusions The presented cases (all of them underwent periaortic lymphadenectomy) suggest that lymph node involvement in renal AML may be more frequent than expected (1-2% of all AMLs) on the basis of the few reported cases. The discordant DNA ploidy (renal versus lymph node lesions) observed in one of the cases with multicentric AML implies synchronous tumor growth at different sites rather than metastatic disease. The intimate coexistance of RCC and AML (RCC revealed by immunohistochemistry within a larger mass of renal AML) may indicate that malignant transformation of an AML should only be accepted, if such a coincidence is unequivocally excluded.

Regional lymph node involvement in benign renal angiomyolipoma

1984 ◽  
Vol 34 (4) ◽  
pp. 889-893
Author(s):  
Toshiaki Manabe ◽  
Yoshikazu Tasaka ◽  
Masamichi Amano ◽  
Takeshi Okunobo
Keyword(s):  
Lymph Node ◽  
Regional Lymph Node ◽  
Lymph Node Involvement ◽  
Renal Angiomyolipoma ◽  
Regional Lymph Node Involvement ◽  
Node Involvement

Sinus histiocytosis with massive lymphadenopathy: a case report and literature review

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Jianying Feng ◽  
Tiantian Han ◽  
Fuyong Jiao
Keyword(s):  
Lymph Node ◽  
Clinical Manifestations ◽  
Morphological Diversity ◽  
Lymph Node Involvement ◽  
Sinus Histiocytosis ◽  
Skin Damage ◽  
Neck Lymph Node ◽  
Massive Lymphadenopathy ◽  
High Gamma ◽  
Node Involvement

Sinus histiocytosis with with massive lymphadenopathy is a benign lymphoproliferative disorder.In 1969, Rosai and Dorfman[1] made detailed research on it, so it was also called Rosai DorfnlRn disease (rosai.dorfmandisease, RDD).The clinical manifestations were fever, neck lymph node enlargement, leukocytosis and high gamma globulin.Histopathological findings showed that lymph node involvement was present in group RDD, and the infiltration of the cells was predominant, especially the phagocytosis of the histiocytic cells.About 43% of RDD patients have lymph node involvement in [2], in which the skin is the most common extranodal organs involved.About 10% of patients with skin damage, skin rash and morphological diversity, is easy to be misdiagnosed.In this paper, through the analysis of a case of RDD and EB virus infection, in clinical in patients with special infection can be early detection and treatment.

545 INCIDENCE OF INVOLVEMENT OF PARATRACHEAL LYMPHNODES IN SIEWERT AEG-I TUMORS

2021 ◽  
Vol 34 (Supplement_1) ◽  
Author(s):  
Johannes Zacherl ◽  
Wolfgang Radlspöck ◽  
Said Albinni ◽  
Cordula Höfle ◽  
Viktoria Kertesz ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Vena Cava ◽  
Lymph Node Involvement ◽  
Type I ◽  
Transthoracic Esophagectomy ◽  
Observation Study ◽  
Ivor Lewis ◽  
Node Involvement ◽  
The Right

Abstract   Transthoracic esophagectomy with 2-field-lymphadenectomy (LAD) is the state of the art treatment of resectable adenocarcinoma of the distal esophagus (Siewert-Stein AEG type I) and may be performed in AEG II cardia cancers. However, it remains unclear whether paratracheal LAD contributes to a survival benefit. In this study we collected data regarding lymph node involvement of paratracheal nodes. Methods From 2014 to 2019 consecutive patients were included in the prospective analysis. Patients underwent hybrid or open Ivor Lewis esophagectomy and 2-field LAD. Paratracheal tissue was removed from the right side of the trachea along the superior vena cava above the azygos vein up to the the upper thoracic aperture. Paratracheal lymph nodes were histologically evaluated separately from the nodes of other stations. Results Ninety-five consecutive patients (12 were female, mean age 67, sd 10, AEG I 84, AEG II 11) were included in the prospective observation study. Seventy-two and 5 patients preoperatively received chemotherapy or radiochemotherapy, respectively. All of them underwent transthoracic esophagectomy (Ivor Lewis 93, McKeown 2—because of coexisting ultralong segment Barrett esophagus). Overall the mean (sd) lymph node count was 37 (12). In the right paratracheal region we found a median of 6 lymph nodes (range;1–22). In 42 (44%) patients positive lymph nodes were recorded, but there was no case with right paratracheal node involvement. Conclusion In the present study paratracheal lymph node involvement was evaluated after transthoracic esophagecotmy with 2-field lymphadenectomy. Remarkably, despite a high proportion of overall lymphatic involvement we did not observe any paratracheal nodal metastasis. Larger studies may show whether paratracheal lyphmadenectomy is necessary during radical esophagectomy for AEG I and AEG II cancers.

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