scholarly journals The Importance of Changes in Body Temperature in Paediatric Surgery and Anaesthesia

1973 ◽  
Vol 1 (6) ◽  
pp. 480-485 ◽  
Author(s):  
Nerida M. Dilworth
Keyword(s):  
Body Temperature ◽  
Newborn Infant ◽  
Paediatric Anaesthesia ◽  
Considerable Importance ◽  
Accidental Hypothermia ◽  
Paediatric Surgery ◽  
Normal Body Temperature ◽  
Normal Body ◽  
The Subject

An understanding of the maintenance of normal body temperature, and the manner in which surgery, anaesthesia, and related procedures may disturb thermoregulation, is of considerable importance in paediatric anaesthesia. The subject of accidental hypothermia, with particular reference to the newborn infant, is reviewed; and hyperpyrexia is briefly discussed.

Effects of successive carbon monoxide exposures on delayed neuronal death in mice under the maintenance of normal body temperature

1991 ◽  
Vol 179 (2) ◽  
pp. 836-840 ◽  
Author(s):  
Hirohisa Ishimaru ◽  
Toshitaka Nabeshima ◽  
Akira Katoh ◽  
Hirotaka Suzuki ◽  
Taneo Fukuta ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Body Temperature ◽  
Neuronal Death ◽  
Delayed Neuronal Death ◽  
Normal Body Temperature ◽  
Normal Body

scholarly journals Distribution of Pediatric Vital Signs in the Emergency Department: A Nationwide Study

Children ◽  
2020 ◽  
Vol 7 (8) ◽  
pp. 89
Author(s):  
Woori Bae ◽  
Kyunghoon Kim ◽  
Bongjin Lee
Keyword(s):  
Emergency Department ◽  
Heart Rate ◽  
Body Temperature ◽  
Respiratory Rate ◽  
Life Support ◽  
Vital Signs ◽  
Reference Ranges ◽  
Normal Body Temperature ◽  
Heart Rates ◽  
Normal Body

To effectively use vital signs as indicators in children, the magnitude of deviation from expected vital sign distribution should be determined. The purpose of this study is to derive age-specific centile charts for the heart rate and respiratory rate of the children who visited the emergency department. This study used the Korea’s National Emergency Department Information System dataset. Patients aged <16 years visiting the emergency department between 1 January 2016 and 31 December 2017 were included. Heart rate and respiratory rate centile charts were derived from the population with normal body temperature (36 to <38 °C). Of 1,901,816 data points retrieved from the database, 1,454,372 sets of heart rates and 1,458,791 sets of respiratory rates were used to derive centile charts. Age-specific centile charts and curves of heart rates and respiratory rates showed a decline in heart rate and respiratory rate from birth to early adolescence. There were substantial discrepancies in the reference ranges of Advanced Paediatric Life Support and Pediatric Advanced Life Support guidelines. Age-based heart rate and respiratory rate centile charts at normal body temperature, derived from children visiting emergency departments, serve as new evidence-based data and can be used in follow-up studies to improve clinical care for children.

scholarly journals Range for Normal Body Temperature in Hemodialysis Patients and Its Comparison with That of Healthy Individuals

2010 ◽  
Vol 114 (4) ◽  
pp. c303-c308 ◽  
Author(s):  
Rabia Hasan ◽  
Mehreen Adhi ◽  
Syed Faisal Mahmood ◽  
Fatima Noman ◽  
Safia Awan ◽  
...  
Keyword(s):  
Body Temperature ◽  
Hemodialysis Patients ◽  
Healthy Individuals ◽  
Normal Body Temperature ◽  
Normal Body

Hemostasis and Thrombosis in Extreme Temperatures (Hypo- and Hyperthermia)

2018 ◽  
Vol 44 (07) ◽  
pp. 651-655 ◽  
Author(s):  
Marcel Levi
Keyword(s):  
Body Temperature ◽  
Clinical Effects ◽  
Bleeding Tendency ◽  
Extreme Temperatures ◽  
Consumption Coagulopathy ◽  
Optimal Temperature ◽  
Prothrombotic State ◽  
Normal Body Temperature ◽  
Cellular Receptors ◽  
Normal Body

AbstractThe delicate biochemistry of coagulation and anticoagulation is greatly affected by deviations from the optimal temperature required for the interactions between various coagulation enzymes, cellular receptors, and intracellular mechanisms. Hyperthermia will lead to a prothrombotic state and, if sufficiently severe such as in heatstroke, a consumption coagulopathy, which will clinically manifest with the simultaneous appearance of intravascular thrombotic obstruction and an increased bleeding tendency. Hypothermia slows down the coagulation process, but as this seems to be adequately balanced by impairment of anticoagulant and fibrinolytic processes, its clinical effects are modest; however, hypothermia may be modestly linked to a somewhat higher risk of localized thrombosis. Restoration of a normal body temperature in patients affected by hyper- or hypothermia is the cornerstone for the management of associated coagulation derangements.

Effects of Temperature and Volatile Anesthetics on GABAAReceptors 

1999 ◽  
Vol 90 (2) ◽  
pp. 484-491 ◽  
Author(s):  
Andrew Jenkins ◽  
Nicholas P. Franks ◽  
William R. Lieb
Keyword(s):  
Body Temperature ◽  
General Anesthesia ◽  
Volatile Anesthetic ◽  
Gaba Concentration ◽  
Normal Body Temperature ◽  
Gaba A ◽  
Normal Body ◽  
Anesthetic Agents ◽  
Receptor Channel

Background Potentiation of the activity of the gamma-aminobutyric acid type A (GABA(A)) receptor channel by volatile anesthetic agents is usually studied in vitro at room temperature. Systematic variation of temperature can be used to assess the relevance of this receptor to general anesthesia and to characterize the modulation of its behavior by volatile agents at normal body temperature. Methods Potentiation of the GABA(A) receptor by halothane, sevoflurane, isoflurane, and methoxyflurane was studied at six temperatures in the range 10-37 degrees C using the whole-cell patch-clamp technique and mouse fibroblast cells stably transfected with defined GABA(A) receptor subunits. Results Control GABA concentration-response plots showed small and physically reasonable changes in the GABA concentration required for a half-maximal effect, the Hill coefficient, and maximal response over the range 10-30 degrees C. Potentiations of GABA (1 microM) responses by aqueous minimum alveolar concentrations of the volatile anesthetic agents decreased with increasing temperature from 10-37 degrees C in an agent-specific manner (methoxyflurane &gt; isoflurane &gt; sevoflurane &gt; halothane) but tended to equalize at normal body temperature (37 degrees C). These findings are in line with published results on the temperature dependence of anesthetic potencies in animals. Conclusions These results are consistent with direct binding of volatile anesthetic agents to the GABA(A) receptor channel playing an important role in general anesthesia. The finding that the degree of anesthetic potentiation was agent-specific at low temperatures but not at 37 degrees C emphasizes the importance of doing in vitro experiments at normal body temperature.

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