Origin of Glycosylated Hemoglobin Al in Chronic Renal Failure

1983 ◽  
Vol 6 (2) ◽  
pp. 77-82 ◽  
Author(s):  
S. De Marchi ◽  
E. Cecchin ◽  
C. Camurri ◽  
P. Quaia ◽  
A. Raimondi ◽  
...  

In chronic renal failure both HbAI and HbAlc levels have been reported to be elevated. In order to investigate the causes of such increase we measured HbAI (cation-exchange chromatography), blood urea nitrogen, arterial blood pH, plasma bicarbonate, phosphatemia, serum iron and serum ferritin before dialysis in 60 uremic patients receiving long term hemodialysis. The increased levels of HbAI do not correlate with glucose intolerance, phosphatemia, blood urea nitrogen, time averaged concentration of urea, serum iron and serum ferritin. On the contrary the presence of a highly significant correlation between HbAI and arterial blood pH (p < 0.001) and between HbAI and plasma bicarbonate (p < 0.001) seems to emphasize a major role for acidosis in increasing the HbAI levels in uremic patients on long term hemodialysis.

1978 ◽  
Vol 67 (5) ◽  
pp. 504-509
Author(s):  
Akira SAITO ◽  
Kenji MAEDA ◽  
Masao SHIBATA ◽  
Kaizo KOBAYASHI ◽  
Satoshi SUGIYAMA ◽  
...  

Author(s):  
Rihab Akasha Mohammed ◽  
Sara M. Siddig ◽  
Mohammed A. Mahdi ◽  
Adil A. Babiker

Background:  The incidence of renal failure, and potentially of CRF, is increasing steadily in Sudan. Anaemia is an accompaniment and independent risk factor for the development of cardiac dysfunction along with other complications. It is also responsible for 40-50% deaths in CRF patients. For this reason, the quick and accurate diagnosis of anaemia should help in decreasing the morbidity caused by CRF. The correction of anaemia, e.g. by the administration of iron supplements and/or erythropoietin, should help improving the general outcome of CRF. methods: Fifty patients with chronic renal failure, already diagnosed clinically and on laboratory basis were selected as a sample group. Another 50 healthy individuals not known to have renal disease were selected as a control group. 5 ml of venous blood was collected in lithium heparin container for iron and ferritin. Concentration of iron was measured by colorimetric method by using SPINREACT™ and serum ferritin by Turbilatex-Ferritin kit. The data obtained were analyzed by using statistical package for social science (SPSS) on programmed computer. Results: The mean ± SD of serum ferritin was calculated in patients and controls and it was found 72 μg/L ± 16.2  for patients and 96 μg/L ± 19.7 for controls the (p-value 0.000). Also the mean ± SD of serum iron was obtain from patients and controls and was found 41μg/dL ± 29.2 and 87 μg/dL ± 47.5 respectively with (p-value = 0.000). There were a weak negative correlation between serum iron and serum ferritin concentrations in patients and controls (R -0.161). Conclusion: The study concludes that serum iron and ferritin levels in CRF patients are significantly low in comparison to healthy controls.


1970 ◽  
Vol 1 (1) ◽  
Author(s):  
LI Yang

Objective To study the efficacy and safety of rhubarb aconite decoction combined with acupoint application in the treatment of chronic renal failure (CRF). Methods 106 cases of CRF patients were randomly divided into two groups, the control group of 53 cases of conventional Western medicine treatment, the treatment group of 53 cases of rhubarb aconite combined with acupoint application, 2 groups were treated continuously for 20 d. (UA), blood urea nitrogen (BUN) and endogenous creatinine clearance (Ccr) were measured before and after treatment. The levels of serum creatinine (Cr), serum creatinine (UA), blood urea nitrogen (BUN) and endogenous creatinine clearance (Ccr) were measured and compared. Level, and observe the occurrence of adverse reactions during the two groups of treatment.


1975 ◽  
Vol 80 (1_Suppla) ◽  
pp. S141 ◽  
Author(s):  
H. D. Bundschu ◽  
E. H. Pfeiffer ◽  
M. Eichner ◽  
K. Hayduk

1997 ◽  
Vol 12 (7) ◽  
pp. 1376-1380 ◽  
Author(s):  
L. J. Petersen ◽  
J. R. Petersen ◽  
U. Talleruphuus ◽  
S. D. Ladefoged ◽  
J. Mehlsen ◽  
...  

Nephrology ◽  
2003 ◽  
Vol 8 (3) ◽  
pp. 110-115 ◽  
Author(s):  
HOLGER REINECKE ◽  
ANDREA REGETMEIER ◽  
FRITZ MATZKIES ◽  
GUNTER BREITHARDT ◽  
ROLAND M SCHAEFER

1991 ◽  
Vol 9 (2) ◽  
pp. 70-73 ◽  
Author(s):  
M.J. Walshaw ◽  
R. Lim ◽  
R. Ahmad ◽  
C.R.K. Hind

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