Biochemical and Immunological Studies in Calves Living over Three Months with a Total Artificial Heart

1992 ◽  
Vol 15 (2) ◽  
pp. 120-125 ◽  
Author(s):  
K. Cídl ◽  
M. Dostál ◽  
JAN Vašků ◽  
J. Nečas ◽  
P. Dobša'k
Keyword(s):  
Lactate Dehydrogenase ◽  
Liver Function ◽  
Central Venous Pressure ◽  
Artificial Heart ◽  
Serum Proteins ◽  
Antihypertensive Drugs ◽  
Venous Pressure ◽  
Total Artificial Heart ◽  
Central Venous

Changes in serum proteins, enzymes and isoenzymes of lactate dehydrogenase (LDH) were compared in long-term surviving calves with a total artificial heart without influencing their central venous pressure (CVP) and calves in which CVP was lowered by antihypertensive drugs administered from day 60 to the end of the experiment. Antihypertensive drugs helped keep CVP within physiological levels for longer and aided liver function as well as evidenced by the different values for the parameters studied in the two groups.

The Applicability of Experimental Experience with the Total Artificial Heart to its Clinical Use

1992 ◽  
Vol 15 (5) ◽  
pp. 307-311 ◽  
Author(s):  
J. Vašků ◽  
P. Urbánek ◽  
M. Dostál ◽  
Jan Vašků
Keyword(s):  
Clinical Application ◽  
Artificial Heart ◽  
Venous Pressure ◽  
Early Period ◽  
Total Artificial Heart ◽  
Blood Coagulation Disorders ◽  
Clinical Use ◽  
Long Term Experiments ◽  
Long Term Experiment

Long-term experiments with the total artificial heart (TAH) are a source of valuable knowledge for later clinical application. Our observations result from 66 long-term experiments on calves and one goat ranging from 30 to 314 days, which have shown the main possible complications in the early period (one month) and later in the experiment. Problems until the second month of pumping concern the clinical pendant of the TAH as a bridge for transplantation, i.e. surgical problems, blood coagulation disorders, infection etc. Later problems are high venous pressure or arterial hypertension, infection with septic thromboembolization, mineralization of the driving diaphragm, etc., and are more closely comparable to the conditions of permanent clinical use of the TAH. Faultless surgery, device function and the regimen of pumping are essential factors in every long-term experiment, just as in clinical application. Infection is a threat throughout any experiment, as in clinical cases. The TNS-BRNO-VII/clin/80 TAH has been implanted in six patients.

scholarly journals Lower initial central venous pressure in septic patients from long-term care facilities than in those from the community

2014 ◽  
Vol 47 (5) ◽  
pp. 422-428 ◽  
Author(s):  
Chun-Yu Lin ◽  
Tun-Chieh Chen ◽  
Po-Liang Lu ◽  
Hui-Juan Chen ◽  
Kebba S. Bojang ◽  
...  
Keyword(s):  
Central Venous Pressure ◽  
Long Term Care ◽  
Venous Pressure ◽  
Central Venous ◽  
Term Care ◽  
Care Facilities

Variability in the establishment of an external reference point for central venous pressure measurement in children

2006 ◽  
Vol 0 (0) ◽  
Author(s):  
Aline S. C. Belela ◽  
Mavilde L. G. Pedreira ◽  
Maria Angélica S. Peterlini ◽  
Denise M. Kusahara ◽  
Werther B. Carvalho ◽  
...  
Keyword(s):  
Central Venous Pressure ◽  
Pressure Measurement ◽  
Reference Point ◽  
Venous Pressure ◽  
Central Venous ◽  
External Reference
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