Can Cyclosporine-A Associated to Methotrexate Maintain Remission Induced by Anti-TNF Agents in Rheumatoid Arthritis Patients? (Cynar Pilot Study)

2010 ◽  
Vol 23 (3) ◽  
pp. 783-790 ◽  
Author(s):  
A. Migliore ◽  
E. Bizzi ◽  
U. Massafra ◽  
F. Vacca ◽  
L.S. Martin Martin ◽  
...  

2016 ◽  
Vol 75 (Suppl 2) ◽  
pp. 1300.2-1300 ◽  
Author(s):  
L. Cano-Garcia ◽  
S. Manrique-Arija ◽  
I. Ureña ◽  
N. Mena-Vazquez ◽  
M.C. Ordoñez-Cañizares ◽  
...  


2011 ◽  
Vol 143 (2) ◽  
pp. 854-862 ◽  
Author(s):  
Artur Mierzecki ◽  
Dorota Strecker ◽  
Krystyna Radomska




2009 ◽  
Vol 2009 ◽  
pp. 1-6 ◽  
Author(s):  
Eman A. Hasan ◽  
David S. Jessop ◽  
Lynsey L. Power ◽  
Paul T. Monk ◽  
John R. Kirwan

Objectives. Hypothalamic-Pituitary-Adrenal axis function may be abnormal in rheumatoid arthritis (RA). A pilot study in 7 patients suggested impaired glucocorticoid feedback in some patients after the dexamethasone-corticotrophin releasing hormone (CRH) test. This study aimed to investigate the dexamethasone-corticotrophin releasing factor test in a larger group of patients and relate the results to characteristics of the disease.Methods. Outpatients with active RA (≥3 swollen and tender joints and C-reactive protein > 10 mg/L) took dexamethasone (1.5 mg) at 23:00 hour in the evening. Next day, baseline saliva and plasma samples were collected, CRH was infused at 11:00 hour, and 4 serial blood and saliva samples were collected. Plasma samples were stored at−80∘Cand a radioimmunoassay performed for saliva and plasma cortisol.Results. All 20 participants showed normal dexamethasone suppression and mounted no response to the CRH challenge. In samples with measurable cortisol, there was a strong correlation between saliva and plasma values (r= 0.876,n= 26,P<.01).Conclusion. No abnormalities were found in the Dexamethasone-CRH test in RA patients in contrast to a previous pilot study. Salivary cortisol measurement may offer an alternative noninvasive technique to plasma cortisol in RA patients in future studies.



2012 ◽  
Vol 251 (1) ◽  
pp. 143-152 ◽  
Author(s):  
Arnd Heiligenhaus ◽  
Beatrix Zurek-Imhoff ◽  
Martin Roesel ◽  
Maren Hennig ◽  
Daniela Rammrath ◽  
...  
Keyword(s):  


2019 ◽  
Vol 97 ◽  
pp. 223-230 ◽  
Author(s):  
Philip Bender ◽  
Andreas Egger ◽  
Martin Westermann ◽  
Nadine Taudte ◽  
Anton Sculean ◽  
...  


2016 ◽  
Vol 30 (3) ◽  
pp. 3-7
Author(s):  
David Suchý ◽  
Ondřej Topolčan ◽  
Jindra Windrichová ◽  
Radka Fuchsová ◽  
Hana Brabcová ◽  
...  


Author(s):  
D. C. Janse Van Rensburg ◽  
J. A. Ker ◽  
C. C. Grant ◽  
L. Fletcher


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