Effectiveness of Ginkgo Biloba in Memory Disorders

1999 ◽  
Vol 12 (3) ◽  
pp. 217-224 ◽  
Author(s):  
Angela J. Massey
Keyword(s):  
Free Radicals ◽  
Ginkgo Biloba ◽  
Platelet Activating Factor ◽  
Memory Disorders ◽  
Bleeding Disorders ◽  
Active Constituents

Numerous trials have been conducted evaluating the efficacy of ginkgo biloba in memory disorders. The active constituents of ginkgo biloba are antioxidants that scavenge free radicals, which have been implicated in the pathogenesis of memory disorders. These studies suggest that ginkgo biloba in doses up to 120 mg/day when taken for 2 years may halt the progression of the disease for at least six months. The biggest concern of using ginkgo biloba is associated with its effects on platelet activating factor, which may result in bleeding disorders. Additional studies are needed to evaluate ginkgo biloba in combination with other medications.

scholarly journals Ultrastructural analysis of kidney, liver and duodenum isolated from treated rats with Ginkgo Biloba extract and effects of this medicinal plant on the biodistribution of the padiopharmaceutical sodium pertechnetate

2008 ◽  
Vol 51 (spe) ◽  
pp. 185-190 ◽  
Author(s):  
Silvana Ramos Farias Moreno ◽  
Jorge José de Carvalho ◽  
Ana Lúcia Nascimento ◽  
Adriano Arnobio ◽  
Beni Olej ◽  
...  
Keyword(s):  
Free Radicals ◽  
Medicinal Plant ◽  
Ginkgo Biloba ◽  
Platelet Activating Factor ◽  
Ultrastructural Level ◽  
Ginkgo Biloba Extract ◽  
Ultrastructural Analysis ◽  
Sodium Pertechnetate ◽  
Kidney Liver

Ginkgo biloba extract (EGb) has been used to treat memory and concentration deficits, acts as platelet activating factor antagonism and prevents against damages caused by free radicals. EGb is a standardized extract that contains 24% flavonoids and 6% terpenoids. The aim of this work was to evaluate the possible influence of an EGb on the ultrastructure of some organs isolated from rats and on the biodistribution of sodium pertechnetate (99mTcO4Na). The animals were treated with EGb and after six days, received 99mTcO4Na. The organs were isolated and fixed for ultrastructural analysis. The results showed that EGb has modified the ultrastructure of kidney, liver and duodenum and altered the biodistribution of 99mTcO4Na (P<0.05). It is speculated that the substances present in the EGb could act directly or generate metabolites capable to promote changes on the biodistribution of 99mTcO4Na and on the morphology of organs at ultrastructural level.

Free Radicals Scavengers Attenuate Platelet-Activating Factor (PAF)-And Endotoxin-Induced Intestinal Myoelectric Disturbances in Rats

1991 ◽  
Vol 13 (1) ◽  
pp. 629-632 ◽  
Author(s):  
Laurent Pons ◽  
Marie-Thérèse Droy-Lefaix ◽  
Pierre Braquet ◽  
Lionel Buéno
Keyword(s):  
Free Radicals ◽  
Platelet Activating Factor

scholarly journals Oilseeds as Functional Foods: Content and Composition of Many Phytochemicals and Therapeutic Alternatives

2021 ◽  
Author(s):  
Aicha O. Cherif
Keyword(s):  
Free Radicals ◽  
Cardiovascular Diseases ◽  
Lipid Oxidation ◽  
Human Health ◽  
Functional Foods ◽  
Cross Linking ◽  
Minor Components ◽  
Active Constituents ◽  
Dna Mutations ◽  
Therapeutic Alternatives

Oilseeds composition has been studied extensively, but recently it has been thoroughly investigated considering especially the phytochemicals representing the minor components. This interest is connected with the activity of such compounds against cardiovascular diseases, lipid oxidation, protein cross-linking and DNA mutations and hemostasis function, which prevent the attack of biomolecules by free radicals. This chapter book could aim to give an overview of the different uses of several oilseeds as bioactive foods, focusing on their active constituents (phytosterols, polyphenols, tocopherols, tocotrienols, and carotenoids) and their content in oilseeds. We will also focus on the beneficial aspects of theses nutraceuticals in human health.

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