The X-ray Crystal Structure of the Sulfonated Azo Dye Congo Red, a Non-Peptidic Inhibitor of HIV-1 Protease which also Binds to Reverse Transcriptase and Amyloid Proteins

1995 ◽  
Vol 6 (1) ◽  
pp. 25-33 ◽  
Author(s):  
W. H. Ojala ◽  
C. R. Ojala ◽  
W. B. Gleason
Keyword(s):  
Crystal Structure ◽  
Reverse Transcriptase ◽  
Congo Red ◽  
Azo Dye ◽  
Amyloid Proteins ◽  
X Ray ◽  
Sulfonated Azo Dye ◽  
Hiv 1

scholarly journals Improved cyclic urea inhibitors of the HIV-1 protease: synthesis, potency, resistance profile, human pharmacokinetics and X-ray crystal structure of DMP 450

1996 ◽  
Vol 3 (4) ◽  
pp. 301-314 ◽  
Author(s):  
C. Nicholas Hodge ◽  
Paul E. Aldrich ◽  
Lee T. Bacheler ◽  
Chong-Hwan Chang ◽  
Charles J. Eyermann ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Human Pharmacokinetics ◽  
Resistance Profile ◽  
X Ray ◽  
Hiv 1

Crystal Structure of HIV-1 Reverse Transcriptase Bound to a Non-Nucleoside Inhibitor with a Novel Mechanism of Action

2010 ◽  
Vol 122 (10) ◽  
pp. 1849-1852 ◽  
Author(s):  
Séverine Freisz ◽  
Guillaume Bec ◽  
Marco Radi ◽  
Philippe Wolff ◽  
Emmanuele Crespan ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Reverse Transcriptase ◽  
Mechanism Of Action ◽  
Hiv 1

scholarly journals Detecting Allosteric Sites of HIV-1 Reverse Transcriptase by X-ray Crystallographic Fragment Screening

2013 ◽  
Vol 56 (7) ◽  
pp. 2738-2746 ◽  
Author(s):  
Joseph D. Bauman ◽  
Disha Patel ◽  
Chhaya Dharia ◽  
Marc W. Fromer ◽  
Sameer Ahmed ◽  
...  
Keyword(s):  
Reverse Transcriptase ◽  
X Ray ◽  
Fragment Screening ◽  
Allosteric Sites ◽  
Hiv 1

scholarly journals Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA

2001 ◽  
Vol 20 (6) ◽  
pp. 1449-1461 ◽  
Author(s):  
Stefan G. Sarafianos ◽  
Kalyan Das ◽  
Chris Tantillo ◽  
Arthur D. Clark ◽  
Jianping Ding ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Reverse Transcriptase ◽  
Polypurine Tract ◽  
Hiv 1

scholarly journals Structural investigation of the HIV-1 reverse transcriptase initiation complex by HDX, SAXS, CryoEM and X-ray crystallography

2017 ◽  
Vol 73 (a1) ◽  
pp. a286-a286
Author(s):  
Chelsy Chesterman ◽  
Steven Tuske ◽  
Jie Zheng ◽  
Youngmin Jeon ◽  
Cheng Zhang ◽  
...  
Keyword(s):  
Reverse Transcriptase ◽  
Structural Investigation ◽  
Initiation Complex ◽  
X Ray ◽  
X Ray Crystallography ◽  
Hiv 1

scholarly journals Design of HIV-1 Protease Inhibitors with C3-Substituted Hexahydrocyclopentafuranyl Urethanes as P2-Ligands: Synthesis, Biological Evaluation, and Protein–Ligand X-ray Crystal Structure

2011 ◽  
Vol 54 (16) ◽  
pp. 5890-5901 ◽  
Author(s):  
Arun K. Ghosh ◽  
Bruno D. Chapsal ◽  
Garth L. Parham ◽  
Melinda Steffey ◽  
Johnson Agniswamy ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Protease Inhibitors ◽  
Biological Evaluation ◽  
X Ray ◽  
Hiv 1

Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

Science ◽  
1992 ◽  
Vol 256 (5065) ◽  
pp. 1783-1790 ◽  
Author(s):  
L. Kohlstaedt ◽  
J Wang ◽  
J. Friedman ◽  
P. Rice ◽  
T. Steitz
Keyword(s):  
Crystal Structure ◽  
Reverse Transcriptase ◽  
Hiv 1
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