Dopamine-D2-Receptor Blockade Reverses the Association Between Trait Approach Motivation and Frontal Asymmetry in an Approach-Motivation Context

2013 ◽  
Vol 24 (4) ◽  
pp. 489-497 ◽  
Author(s):  
Jan Wacker ◽  
Erik M. Mueller ◽  
Diego A. Pizzagalli ◽  
Jürgen Hennig ◽  
Gerhard Stemmler
Keyword(s):  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Approach Motivation ◽  
Receptor Blockade ◽  
Frontal Asymmetry ◽  
Dopamine D2

Relevance of the dopamine D2 receptor blockade in clinical response to neuroleptic treatment in schizophrenic patients

1989 ◽  
Vol 2 (1-2) ◽  
pp. 207
Author(s):  
Ana Hitri ◽  
Parvathi Mohan ◽  
Dharmber Sinha ◽  
James Harrold ◽  
BruceI. Diamond ◽  
...  
Keyword(s):  
Clinical Response ◽  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Receptor Blockade ◽  
Neuroleptic Treatment ◽  
Dopamine D2 ◽  
Schizophrenic Patients

Dopamine D2 Receptor Blockade and Antimigraine Action of Flunarizine

Cephalalgia ◽  
1994 ◽  
Vol 14 (3) ◽  
pp. 235-240 ◽  
Author(s):  
C Wöber ◽  
T Brücke ◽  
C Wöber-Bingöl ◽  
S Asenbaum ◽  
P Wessely ◽  
...  
Keyword(s):  
Single Photon ◽  
Dopamine D2 Receptor ◽  
Photon Emission ◽  
D2 Receptor ◽  
High Specificity ◽  
D2 Receptors ◽  
Binding Potential ◽  
Receptor Blockade ◽  
Dopamine D2

We studied in vivo the influence of flunarizine on dopamine D2 receptors and investigated whether dopamine D2 receptor blockade is involved in its antimigraine action. Eleven migraine patients, treated with flunarizine, 10 mg per day, underwent single photon emission computer tomography (SPECT) using [123I] labeled iodobenzamide, a ligand with high affinity and high specificity for D2 receptors. There was a reduction of the dopamine D2 receptor binding potential in all patients compared to age-matched controls. The efficacy of flunarizine in migraine prophylaxis failed to correlate with the degree of the dopamine D2 receptor blockade. The antimigraine action of flunarizine may not involve antidopaminergic mechanisms.

Two cases of long term dopamine D2 receptor blockade after depot neuroleptics

1993 ◽  
Vol 94 (3) ◽  
pp. 217-221 ◽  
Author(s):  
C. Harasko-van der Meer ◽  
T. Br�cke ◽  
S. Wenger ◽  
P. Fischer ◽  
L. Deecke ◽  
...  
Keyword(s):  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Receptor Blockade ◽  
Dopamine D2 ◽  
Depot Neuroleptics
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