Naloxone and Alcohol Intoxication in the Dog
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1 The effects of naloxone upon ethanol-induced coma have been investigated in dogs. In a double blind study, 15 mongrel dogs received ethanol i.v. (4 g/kg) followed by a single dose of naloxone (12 ?g/kg). 2 Naloxone failed to affect either the duration of respiratory arrest or the time to recovery of motor coordination. In similar animals treated with the narcotic analgesic, fentanyl, naloxone induced a dramatic and complete reversal of the narcotic effects within 30 seconds. 3 It is concluded that, if naloxone has any effect in alcoholic coma, it is not comparable with its dramatic action in narcotic coma.
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2019 ◽
Vol 7
(8)
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pp. 174-174
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1990 ◽
Vol 161
(5)
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pp. 942-947
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2015 ◽
Vol 33
(15_suppl)
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pp. 9629-9629
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1992 ◽
Vol 68
(5)
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pp. 325-327
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2010 ◽
Vol 28
(15_suppl)
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pp. 9021-9021
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1986 ◽
Vol 6
(5)
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pp. 219-227
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