On the use of the modified power series family of distributions in a cure rate model context

2019 ◽  
Vol 29 (7) ◽  
pp. 1831-1845
Author(s):  
Diego I Gallardo ◽  
Yolanda M Gómez ◽  
Héctor W Gómez ◽  
Mário de Castro

In this paper, we propose a generalization of the power series cure rate model for the number of competing causes related to the occurrence of the event of interest. The model includes distributions not yet used in the cure rate models context, such as the Borel, Haight and Restricted Generalized Poisson distributions. The model is conveniently parameterized in terms of the cure rate. Maximum likelihood estimation based on the Expectation Maximization algorithm is discussed. A simulation study designed to assess some properties of the estimators is carried out, showing the good performance of the proposed estimation procedure in finite samples. Finally, an application to a bone marrow transplant data set is presented.

2016 ◽  
Vol 44 (7) ◽  
pp. 1153-1164 ◽  
Author(s):  
Diego I. Gallardo ◽  
Héctor W. Gómez ◽  
Heleno Bolfarine

2021 ◽  
pp. 096228022110529
Author(s):  
Haolun Shi ◽  
Da Ma ◽  
Mirza Faisal Beg ◽  
Jiguo Cao

Existing survival models involving functional covariates typically rely on the Cox proportional hazards structure and the assumption of right censorship. Motivated by the aim of predicting the time of conversion to Alzheimer’s disease from sparse biomarker trajectories in patients with mild cognitive impairment, we propose a functional mixture cure rate model with both functional and scalar covariates for interval censoring and sparsely sampled functional data. To estimate the nonparametric coefficient function that depicts the effect of the shape of the trajectories on the survival outcome and cure probability, we utilize the functional principal component analysis to extract the functional features from the sparsely and irregularly sampled trajectories. To obtain parameter estimates from the mixture cure rate model with interval censoring, we apply the expectation-maximization algorithm based on Poisson data augmentation. The estimation accuracy of our method is assessed via a simulation study and we apply our model on Alzheimer’s disease Neuroimaging Initiative data set.


2015 ◽  
Vol 16 (17) ◽  
pp. 7923-7927 ◽  
Author(s):  
Ahmad Reza Baghestani ◽  
Farid Zayeri ◽  
Mohammad Esmaeil Akbari ◽  
Leyla Shojaee ◽  
Naghmeh Khadembashi ◽  
...  

2008 ◽  
Vol 23 (4) ◽  
pp. 251-259 ◽  
Author(s):  
Theodora Bejan-Angoulvant ◽  
Anne-Marie Bouvier ◽  
Nadine Bossard ◽  
Aurelien Belot ◽  
Valérie Jooste ◽  
...  

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