scholarly journals Measuring maternal serum screening markers for Down’s syndrome in plasma collected for cell-free DNA testing

2016 ◽  
Vol 24 (3) ◽  
pp. 113-119 ◽  
Author(s):  
Geralyn M Lambert-Messerlian ◽  
Elizabeth E Eklund ◽  
Louis M Neveux ◽  
Glenn E Palomaki
Keyword(s):  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Maternal Serum ◽  
Dna Testing ◽  
Maternal Serum Screening ◽  
Cell Free Dna ◽  
Free Dna ◽  
Serum Screening

Prenatal Screening

2018 ◽  
Author(s):  
Amber Mathiesen ◽  
Kali Roy
Keyword(s):  
Test Performance ◽  
Predictive Value ◽  
Prenatal Screening ◽  
Maternal Serum ◽  
Dna Testing ◽  
Maternal Serum Screening ◽  
Cell Free Dna ◽  
Free Dna ◽  
Serum Screening

This chapter provides information about a genetic counselor’s role in prenatal screening, including discussing and offering options to a patient, interpreting and providing results, or managing referrals based on abnormal results. It discusses how a screen is evaluated using sensitivity, specificity, positive predictive value, negative predictive value, and personal utility. It provides a detailed description of both maternal serum screening and cell-free DNA testing. The maternal serum screening discussion includes information on multiples of median, calculating risk, timing, pattern association, limitations, and follow-up. The review of cell-free DNA testing includes fetal fraction, methodology, test performance, limitations and considerations for testing, and follow-up. This chapter also provides a list of additional resources to use for cell-free DNA testing.

Maternal serum screening for Down's syndrome

Public Health ◽  
1997 ◽  
Vol 111 (6) ◽  
pp. 383-385
Author(s):  
S Fairgrieve ◽  
D Magnay ◽  
I White ◽  
J Burn
Keyword(s):  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Maternal Serum ◽  
Maternal Serum Screening ◽  
Serum Screening
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