Combined DOG1 and Mammaglobin Immunohistochemistry Is Comparable to ETV6-breakapart Analysis for Differentiating Between Papillary Cystic Variants of Acinic Cell Carcinoma and Mammary Analogue Secretory Carcinoma

2016 ◽  
Vol 25 (2) ◽  
pp. 127-140 ◽  
Author(s):  
Nasser Said-Al-Naief ◽  
Roman Carlos ◽  
Gail H. Vance ◽  
Caroline Miller ◽  
Paul C. Edwards
2016 ◽  
Vol 140 (9) ◽  
pp. 997-1001 ◽  
Author(s):  
Todd M. Stevens ◽  
Vishwas Parekh

Mammary analogue secretory carcinoma (MASC) is a recently described salivary gland tumor that shares the same histologic appearance and ETV6 gene (12p13) rearrangement as secretory carcinoma of the breast. Prior to its recognition, MASC cases were commonly labeled acinic cell carcinoma and adenocarcinoma, not otherwise specified. Despite distinctive histologic features, MASC may be difficult to distinguish from other salivary gland tumors, in particular zymogen-poor acinic cell carcinoma and low-grade salivary duct carcinoma. Although characteristic morphologic and immunohistochemical features form the basis of a diagnosis of MASC, the presence of an ETV6-NTRK3 gene fusion is confirmatory. Given its recent recognition the true prognostic import of MASC is not yet clearly defined.


2019 ◽  
Vol 276 (12) ◽  
pp. 3461-3466 ◽  
Author(s):  
Tetsuya Terada ◽  
Ryo Kawata ◽  
Keiki Noro ◽  
Masaaki Higashino ◽  
Shuji Nishikawa ◽  
...  

Author(s):  
Yuichiro Hamamoto ◽  
Hiroshi Harada ◽  
Masaharu Kohara ◽  
Keiichiro Honma ◽  
Shin-ichi Nakatsuka ◽  
...  

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