Keratin Granulomas in the Peritoneum on Frozen Section: A Case Report with Multiple Suspects and the Search for the Culprit

2021 ◽  
pp. 106689692110160
Author(s):  
Levon Katsakhyan ◽  
Xiaoming Zhang ◽  
Maria C. Reyes ◽  
Lauren E. Schwartz ◽  
Ashley F. Haggerty ◽  
...  
Keyword(s):  
Case Report ◽  
Dermoid Cyst ◽  
Frozen Section ◽  
Endometrioid Adenocarcinoma ◽  
Diagnostic Significance ◽  
Rare Finding ◽  
Fertility Sparing ◽  
Endometrial Endometrioid Adenocarcinoma

Keratin granulomas in the peritoneum are a rare finding with multiple etiologies and can be especially challenging for both the pathologist and the surgeon when these lesions are grossly visible. We report a case of a unique frozen section diagnostic scenario of evaluation of keratin granulomas in the peritoneum of a 47-year-old woman in the setting of multiple potential culprits: endometrial endometrioid adenocarcinoma following fertility sparing treatment, and a concurrent dermoid cyst. We discuss the various etiologies of keratin granulomas in the peritoneum, mechanism of their formation, diagnostic significance, as well as implications of fertility sparing treatments. To the best of our knowledge, this is the only case of keratin granulomas in the peritoneum with multiple distinct potential pathologic culprits as well the only case following fertility sparing treatment.

scholarly journals Collision tumor of ovary: a case report on bilateral dermoid cyst with co-existing unilateral mucinous cystadenoma

2020 ◽  
Vol 9 (7) ◽  
pp. 3078
Author(s):  
Sowmya Sampurna Maddipati ◽  
Sudha C. P. ◽  
Sowmya K.
Keyword(s):  
Case Report ◽  
Dermoid Cyst ◽  
Frozen Section ◽  
Mucinous Cystadenoma ◽  
Cystic Teratoma ◽  
Collision Tumor ◽  
Ovarian Tumors ◽  
Favourable Prognosis ◽  
Benign Cystic Teratoma ◽  
Mucinous Ovarian Tumors

A collision tumor is the coexistence of two adjacent, but histologically distinct tumors without histological admixture in the same tissue or organ. Such tumors have often been reported in various organs, but location in the ovary is rare. The juxtaposition with dermoid cysts has been reported as comprising approximately 5% of benign mucinous ovarian tumors and rare examples of proliferating mucinous tumors. Authors are reporting a case of collision tumor which included benign mucinous cystadenoma and benign cystic teratoma. The gynecologists and pathologists should be aware of such combination of tumors. The case was diagnosed post-operatively. It is important to correctly diagnose the component of tumor for further management and favourable prognosis. Frozen section intra-operatively plays an important role in diagnosing such tumors.

High expression of cyclin A is associated with poor prognosis in endometrial endometrioid adenocarcinoma

Tumor Biology ◽  
2014 ◽  
Vol 35 (6) ◽  
pp. 5395-5399 ◽  
Author(s):  
Simi Santala ◽  
Anne Talvensaari-Mattila ◽  
Ylermi Soini ◽  
Maria Honkavuori-Toivola ◽  
Markku Santala
Keyword(s):  
Poor Prognosis ◽  
Cyclin A ◽  
High Expression ◽  
Endometrioid Adenocarcinoma ◽  
Endometrial Endometrioid Adenocarcinoma
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