Gliotic tissue simulating a macular neovascularization in full-thickness macular hole

2021 ◽  
pp. 112067212110295
Author(s):  
Chiara Vigano’ ◽  
Enrico Borrelli ◽  
Riccardo Sacconi ◽  
Maria Brambati ◽  
Francesco Bandello ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Pigment Epithelium ◽  
Macular Hole ◽  
Male Patient ◽  
Vascular Tissue ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Full Thickness ◽  
Macular Holes ◽  
Full Thickness Macular Hole

The authors report a case of a male patient affected by macular hole. In particular, a hyperreflective tissue was found on optical coherence tomography (OCT) examination in macular region, just above the retinal pigment epithelium (RPE). OCT angiography (OCTA) did not show the presence of vascular tissue, thus the hyperreflective material was ascribed to primary gliotic tissue. This case highlights the ability for Müller cells placed near macular holes to migrate up to the RPE and to produce gliotic tissue.

Full-thickness macular hole associated with congenital simple hamartoma of retinal pigment epithelium (CSHRPE)

2017 ◽  
Vol 38 (5) ◽  
pp. 2179-2182 ◽  
Author(s):  
Panagiotis Stavrakas ◽  
Athanasios Vachtsevanos ◽  
Efthymia Karakosta ◽  
Nikos Kozeis ◽  
Magdalini Triantafylla ◽  
...  
Keyword(s):  
Retinal Pigment Epithelium ◽  
Macular Hole ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Full Thickness ◽  
Full Thickness Macular Hole

Study of Role of Optical Coherence Tomography in the Interpretation of Common Macular Disorders at a Tertiary Eye Care Centre in Rural Maharashtra

2021 ◽  
Vol 8 (27) ◽  
pp. 2428-2433
Author(s):  
Uttam Haribhau Nisale ◽  
Varsha Ramesh Dhakne ◽  
Sourabh Hanumant Karad ◽  
Samarth Babasaheb Waghambare ◽  
Hanumant Tulshiram Karad ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Pigment Epithelium ◽  
Macular Hole ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Age Related ◽  
Macular Diseases ◽  
Myopic Maculopathy

BACKGROUND Optical Coherence Tomography (OCT) is a commonly used non invasive imaging instrument useful for the diagnosis and follow up of macular disorders, but it has its own share of drawbacks in the presence of media opacities like corneal oedema, dense cataract and vitreous haemorrhage. We wanted to study and interpret the various patterns of common macular diseases on optical coherence tomography. METHODS 100 patients having macular diseases with no other ocular pathology were selected by simple random sampling. The patients were studied and followed up from day 1 of OPD during the period from January 2019 to December 2019 in rural hospital at Latur. All patients suspected of any macular disorder by slit lamp bio-microscopy with 78D or 90D examination were subjected to OCT evaluation. RESULTS On observation, out of 100 cases of macular pathology, 44 % (44 patients) with age related macular degeneration(ARMD), diabetic macular oedema ( DME) 36 % (36 patients), central serous retinopathy (CSR) 10 % (10 patients), myopic maculopathy (MM) 7 % (7 patients), macular hole (MH) 3 % (3 patients) were found in our study. In ARMD patients our OCT findings were hard drusens in retinal pigment epithelium (RPE), detachment of neurosensory retina and retinal pigment epithelium whereas in patients of DME our OCT findings were cyst like hyporeflective spaces within the retina, with retinal thinning and loss of foveal depression. In patients of CSR our findings were separation of sensory retina from RP, in myopic maculopathy our OCT findings were presence of macular retinoschisis and in patients of MH our findings were showing attachment of the posterior hyaloids to the fovea, separation of a small portion of the sensory retina from RPE in the foveolar region and intraretinal cystic changes. CONCLUSIONS OCT plays a crucial role when added along with the clinical examination in the diagnosis and interpretation of common macular disorders. KEYWORDS Optical Coherence Tomography, Age Related Macular Degeneration, Macular Hole, Myopic Maculopathy

scholarly journals Natural progression of lamellar macular holes in high myopia: a long-term follow-up study

2021 ◽  
Author(s):  
Mary Ho ◽  
Eugenie Mok ◽  
Felix Lai ◽  
Helena PY Sin ◽  
Shaheeda Mohamed ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Macular Hole ◽  
High Myopia ◽  
Full Thickness ◽  
Macular Holes ◽  
Full Thickness Macular Hole ◽  
The Mean

Abstract Background To determine the long-term prognosis of lamellar macular holes (LMH) in highly myopic eyes. Methods This was a retrospective observational study. Patients with LMH associated with high myopia (>-6 dioptres) were examined at regular 6-month intervals for a minimum of 36 months to detect for any structural and functional deterioration. Assessment included visual acuity checking, fundal examination, and optical coherence tomography (OCT) scanning. The risk factors for visual deterioration and progression to full-thickness macular hole (MH) were analysed using Kaplan-Meier survival analysis. The main outcome measures included the changes in mean best-corrected visual acuities, evidence of lamellar hole progression on OCT scans and complication rates of full-thickness macular hole (FTMH), and foveal detachment (FD) development. Results A total of 37 highly myopic eyes with optical coherence tomography confirmed LMH were recruited from 36 patients. The mean age was 63.4 ± 9.8 years and the mean spherical equivalent refractive error was − 9.01 ± 3.6 D with axial length of 27.74 ± 1.45 mm. The mean follow-up duration was 57.6 ± 10.9 months. The mean baseline visual acuity was 0.272 logMAR ± 0.22. A gradual decline in visual acuity was noted, and the change reached statistical significance from 36 months onwards. Visual acuity was 0.648 ± 0.41 logMAR at 36 months (p = 0.034) and 0.604 ± 0.455 at 48 months (p = 0.046). Twelve eyes (32.4%) had foveoschisis at baseline. Coexistence of a lamellar macular hole with foveoschisis was shown to be a risk factor for the development of a FTMH or FD (p = 0.002). Conclusion LMH in highly myopic eyes was generally stable, while a small proportion of patients progressed to full-thickness MH. Patients with coexisting LMH, foveoschisis, and vitreomacular traction had a higher risk of visual decline and progression to full-thickness MH.

Macular hole in combined hamartoma of the retina and retinal pigment epithelium

2021 ◽  
Vol 1 (2) ◽  
pp. 177
Author(s):  
Mohit Dogra ◽  
Atul Arora ◽  
SimarRajan Singh ◽  
Ramandeep Singh
Keyword(s):  
Retinal Pigment Epithelium ◽  
Macular Hole ◽  
Pigment Epithelium ◽  
Retinal Pigment
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