Intralesional Cidofovir in the Treatment of Cutaneous Warts in a Renal Transplant Patient

2012 ◽  
Vol 16 (6) ◽  
pp. 462-464 ◽  
Author(s):  
Marie-Michèle Blouin ◽  
Richard Cloutier ◽  
Réal Noël

Background: Cutaneous warts are often recalcitrant to conventional therapy in immunocompromised patients. Cidofovir is a potent antiviral agent shown to have a broad spectrum of action against DNA virus, including human papillomavirus. Objective: To determine the efficacy of intralesional cidofovir in the treatment of florid warts in an immunocompromised renal transplant patient. Method: The patient received seven injections of intralesional cidofovir at 4 week intervals in his numerous palmar warts. Conclusion: Based on our results, intralesional cidofovir is a promising therapeutic modality in the treatment of cutaneous warts in the renal transplant population. Contexte: Les verrues cutanées se montrent souvent réfractaires au traitement habituel chez les immunodéficients. Le cidofovir est un antiviral puissant, doté d'un large spectre d'action contre les virus à ADN, y compris contre le papillomavirus humain. Objectif: L'étude visait à déterminer l'efficacité du cidofovir intralésionnel dans le traitement de verrues florides chez un patient immunodéprimé, ayant subi une transplantation rénale. Méthode: Le patient a reçu sept injections de cidofovir intralésionnel, à 4 semaines d'intervalle, dans les nombreuses verrues palmaires. Conclusion: D'après les résultats obtenus, le cidofovir intralésionnel serait porteur d'avenir dans le traitement des verrues cutanées chez les patients ayant subi une transplantation rénale.

2020 ◽  
Vol 8 ◽  
pp. 2050313X2095303
Author(s):  
Camille Pennou ◽  
Eileen Javidi ◽  
Julie Lecours ◽  
Annie Bélisle ◽  
Sandra Davar

Trichodysplasia spinulosa is a rare cutaneous disease caused by the trichodysplasia spinulosa–associated polyomavirus. It occurs more frequently in immunocompromised patients, particularly in solid organ transplants. A few successful treatments have been described in the literature. In our report, we present a biopsy-proven trichodysplasia spinulosa case in a kidney transplant recipient who rapidly responded to a reduction of his immunosuppressive therapy.


2012 ◽  
Vol 23 (4) ◽  
pp. e109-e110 ◽  
Author(s):  
Susan John ◽  
John Neary ◽  
Christine H Lee

Bacillus cereusis a common cause of gastrointestinal diseases. The majority of individuals withB cereus-related food poisoning recover without any specific treatment. It can, however, rarely cause invasive disease in immunocompromised patients.


2015 ◽  
Vol 19 (1) ◽  
pp. 66-68 ◽  
Author(s):  
Alexandre Laroche ◽  
Catherine Allard ◽  
Myrna Chababi-Atallah ◽  
Mélanie Masse ◽  
Janie Bertrand

Background: Trichodysplasia spinulosa (TS) is a rare skin affection seen in immunocompromised patients, mainly those with solid organ tranplants. Objective: To report a case of a patient with classic clinical and pathologic findings for the disease so that physicians caring for this population are aware of the clinical presentation. Method: We report the case of a female patient we saw at our clinic with a diagnosis of TS. Results: The diagnosis of TS was confirmed by pathologic findings. Conclusion: TS should be considered in any immunocompromised patient with a papular facial eruption reminiscent of acne vulgaris and with keratotic spiny papules as a distinctive feature.


1999 ◽  
Vol 5 (1) ◽  
pp. 67-69 ◽  
Author(s):  
Balázs Nemes ◽  
Hemangshu Podder ◽  
Jenő Járay ◽  
Gabriella Dabasi ◽  
Laura Lázár ◽  
...  

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