scholarly journals Trichodysplasia spinulosa in a renal transplant patient: A case report of successful treatment

2020 ◽  
Vol 8 ◽  
pp. 2050313X2095303
Author(s):  
Camille Pennou ◽  
Eileen Javidi ◽  
Julie Lecours ◽  
Annie Bélisle ◽  
Sandra Davar

Trichodysplasia spinulosa is a rare cutaneous disease caused by the trichodysplasia spinulosa–associated polyomavirus. It occurs more frequently in immunocompromised patients, particularly in solid organ transplants. A few successful treatments have been described in the literature. In our report, we present a biopsy-proven trichodysplasia spinulosa case in a kidney transplant recipient who rapidly responded to a reduction of his immunosuppressive therapy.

2012 ◽  
Vol 23 (4) ◽  
pp. e109-e110 ◽  
Author(s):  
Susan John ◽  
John Neary ◽  
Christine H Lee

Bacillus cereusis a common cause of gastrointestinal diseases. The majority of individuals withB cereus-related food poisoning recover without any specific treatment. It can, however, rarely cause invasive disease in immunocompromised patients.


2021 ◽  
pp. 367-373
Author(s):  
Ravi Raju Tatapudi ◽  
Venkateswara Rao Kopparti ◽  
Anusha Poosapati ◽  
Srinivas Metta ◽  
Vedita Palli ◽  
...  

COVID-19 pandemic affected millions of people across India. COVID-19 cases are fewer in children with less severity and better outcomes than in adults. However, a small proportion develop severe illness and succumb to the disease. Clinical manifestations and optimal management of COVID-19 in immunocompromised children are not clearly known. Remdesivir was shown to be efficient in reducing the recovery time in COVID-19 patients requiring supplemental oxygen. Remdesivir is approved for use in children with severe COVID-19, but there are no guidelines in patients with risk factors like recent solid organ transplantation. We report a case of a 10-year-old kidney transplant recipient (KTR) infected with severe acute respiratory syndrome corona virus-2, 2.5 months after the transplantation. Unlike most children, he presented with high fever, cough, and vomiting. His inflammatory markers were elevated. In this case report, we discussed management and clinical outcomes of this patient. In view of recent kidney transplantation and the severity of infection with emergent oxygen requirement, we gave him remdesivir. We continued prednisolone and tacrolimus and stopped mycophenolate. He recovered completely in 7 days. We feel that severely immunosuppressed KTR children with COVID-19 will benefit with remdesivir administration. Monitoring tacrolimus trough levels is essential for maintaining adequate immunosuppression.


Author(s):  
Victoria Oakes ◽  
Dinesh Bahl ◽  
Suresh Antony

: Cytomegalovirus (CMV) retinitis in a kidney transplant recipient is a rare illness with only one other reported case in the literature.. We present a case of a 70-year-old kidney transplant recipient female who presented complaining of decreased vision of her right eye. She was diagnosed with CMV retinitis and started on intravenous ganciclovir. After three weeks of therapy, the patient has had no signs of CMV retinitis.. With only one other previous case report of CMV retinitis in a kidney transplant patient, appropriate treatment and predictability of recurrence are unknown.


2015 ◽  
Vol 19 (1) ◽  
pp. 66-68 ◽  
Author(s):  
Alexandre Laroche ◽  
Catherine Allard ◽  
Myrna Chababi-Atallah ◽  
Mélanie Masse ◽  
Janie Bertrand

Background: Trichodysplasia spinulosa (TS) is a rare skin affection seen in immunocompromised patients, mainly those with solid organ tranplants. Objective: To report a case of a patient with classic clinical and pathologic findings for the disease so that physicians caring for this population are aware of the clinical presentation. Method: We report the case of a female patient we saw at our clinic with a diagnosis of TS. Results: The diagnosis of TS was confirmed by pathologic findings. Conclusion: TS should be considered in any immunocompromised patient with a papular facial eruption reminiscent of acne vulgaris and with keratotic spiny papules as a distinctive feature.


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