Trichodysplasia Spinulosa in a Renal Transplant Patient

2015 ◽  
Vol 19 (1) ◽  
pp. 66-68 ◽  
Author(s):  
Alexandre Laroche ◽  
Catherine Allard ◽  
Myrna Chababi-Atallah ◽  
Mélanie Masse ◽  
Janie Bertrand
Keyword(s):  
Renal Transplant ◽  
Renal Transplant Patient ◽  
Transplant Patient ◽  
Clinical Presentation ◽  
Immunocompromised Patient ◽  
Acne Vulgaris ◽  
Solid Organ ◽  
Immunocompromised Patients ◽  
Pathologic Findings ◽  
Skin Affection

Background: Trichodysplasia spinulosa (TS) is a rare skin affection seen in immunocompromised patients, mainly those with solid organ tranplants. Objective: To report a case of a patient with classic clinical and pathologic findings for the disease so that physicians caring for this population are aware of the clinical presentation. Method: We report the case of a female patient we saw at our clinic with a diagnosis of TS. Results: The diagnosis of TS was confirmed by pathologic findings. Conclusion: TS should be considered in any immunocompromised patient with a papular facial eruption reminiscent of acne vulgaris and with keratotic spiny papules as a distinctive feature.

scholarly journals Trichodysplasia spinulosa in a renal transplant patient: A case report of successful treatment

2020 ◽  
Vol 8 ◽  
pp. 2050313X2095303
Author(s):  
Camille Pennou ◽  
Eileen Javidi ◽  
Julie Lecours ◽  
Annie Bélisle ◽  
Sandra Davar
Keyword(s):  
Case Report ◽  
Renal Transplant ◽  
Transplant Recipient ◽  
Immunosuppressive Therapy ◽  
Kidney Transplant ◽  
Renal Transplant Patient ◽  
Transplant Patient ◽  
Kidney Transplant Recipient ◽  
Solid Organ ◽  
Immunocompromised Patients

Trichodysplasia spinulosa is a rare cutaneous disease caused by the trichodysplasia spinulosa–associated polyomavirus. It occurs more frequently in immunocompromised patients, particularly in solid organ transplants. A few successful treatments have been described in the literature. In our report, we present a biopsy-proven trichodysplasia spinulosa case in a kidney transplant recipient who rapidly responded to a reduction of his immunosuppressive therapy.

scholarly journals Gastrointestinal Mucormycosis in a Renal Transplant Patient

2001 ◽  
Vol 15 (4) ◽  
pp. 269-271 ◽  
Author(s):  
Jill Tinmouth ◽  
Jeffrey Baker ◽  
Geoffrey Gardiner
Keyword(s):  
Renal Transplant ◽  
Renal Transplant Patient ◽  
Transplant Patient ◽  
Clinical Course ◽  
Organ Transplant ◽  
Pathological Examination ◽  
Solid Organ ◽  
Resected Tissue ◽  
Solid Organ Transplant Patient ◽  
Organ Transplant Patient

The clinical course and management of a rare case of gastrointestinal mucormycosis occurring in a renal transplant patient are presented. The diagnosis was made on pathological examination of surgically resected tissue from the colon, spleen and stomach. The patient did not survive the infection. To the best of our knowledge, this is the 11th reported case of gastrointestinal mucormycosis in a solid organ transplant patient. The pathophysiology, incidence and prognosis of this disease are discussed.

scholarly journals InvasiveBacillus cereusInfection in a Renal Transplant Patient: A Case Report and Review

2012 ◽  
Vol 23 (4) ◽  
pp. e109-e110 ◽  
Author(s):  
Susan John ◽  
John Neary ◽  
Christine H Lee
Keyword(s):  
Case Report ◽  
Renal Transplant ◽  
Renal Transplant Patient ◽  
Transplant Patient ◽  
Food Poisoning ◽  
Specific Treatment ◽  
Gastrointestinal Diseases ◽  
Invasive Disease ◽  
Immunocompromised Patients ◽  
Common Cause

Bacillus cereusis a common cause of gastrointestinal diseases. The majority of individuals withB cereus-related food poisoning recover without any specific treatment. It can, however, rarely cause invasive disease in immunocompromised patients.

Intralesional Cidofovir in the Treatment of Cutaneous Warts in a Renal Transplant Patient

2012 ◽  
Vol 16 (6) ◽  
pp. 462-464 ◽  
Author(s):  
Marie-Michèle Blouin ◽  
Richard Cloutier ◽  
Réal Noël
Keyword(s):  
Human Papillomavirus ◽  
Renal Transplant ◽  
Renal Transplant Patient ◽  
Transplant Patient ◽  
Antiviral Agent ◽  
Therapeutic Modality ◽  
Immunocompromised Patients ◽  
Dna Virus ◽  
Transplantation Rénale ◽  
Cutaneous Warts

Background: Cutaneous warts are often recalcitrant to conventional therapy in immunocompromised patients. Cidofovir is a potent antiviral agent shown to have a broad spectrum of action against DNA virus, including human papillomavirus. Objective: To determine the efficacy of intralesional cidofovir in the treatment of florid warts in an immunocompromised renal transplant patient. Method: The patient received seven injections of intralesional cidofovir at 4 week intervals in his numerous palmar warts. Conclusion: Based on our results, intralesional cidofovir is a promising therapeutic modality in the treatment of cutaneous warts in the renal transplant population. Contexte: Les verrues cutanées se montrent souvent réfractaires au traitement habituel chez les immunodéficients. Le cidofovir est un antiviral puissant, doté d'un large spectre d'action contre les virus à ADN, y compris contre le papillomavirus humain. Objectif: L'étude visait à déterminer l'efficacité du cidofovir intralésionnel dans le traitement de verrues florides chez un patient immunodéprimé, ayant subi une transplantation rénale. Méthode: Le patient a reçu sept injections de cidofovir intralésionnel, à 4 semaines d'intervalle, dans les nombreuses verrues palmaires. Conclusion: D'après les résultats obtenus, le cidofovir intralésionnel serait porteur d'avenir dans le traitement des verrues cutanées chez les patients ayant subi une transplantation rénale.

Respiratory Syncytial Virus Pneumonia in an Adult Renal Transplant Patient: An Unexpected Nosocomial Infection

2003 ◽  
Vol 24 (7) ◽  
pp. 548-550 ◽  
Author(s):  
Rodrigo Morales ◽  
Michael Kirkpatrick ◽  
Barry Browne ◽  
Osemwegie Emovon
Keyword(s):  
Respiratory Syncytial Virus ◽  
Renal Transplant ◽  
Renal Transplant Patient ◽  
Transplant Patient ◽  
Immunocompromised Patient ◽  
Prevention Of Infection ◽  
Virus Pneumonia ◽  
Mode Of Transmission ◽  
Syncytial Virus ◽  
Adult Renal Transplant Recipient

AbstractThis article describes a case of respiratory syncytial virus pneumonia believed to have been acquired nosocomially in an adult renal transplant recipient. The mode of transmission, diagnosis, and prevention of infection due to this virus in the immunocompromised patient are discussed (Infect Control Hosp Epidemiol2003;24:548-550.

scholarly journals Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Tamim Hamdi ◽  
Vanji Karthikeyan ◽  
George J. Alangaden
Keyword(s):  
Renal Transplant ◽  
Renal Transplant Patient ◽  
Transplant Patient ◽  
Organ Transplant ◽  
Solid Organ ◽  
Transplant Recipients ◽  
Uncontrolled Diabetes ◽  
Solid Organ Transplant Recipients ◽  
Disseminated Mucormycosis ◽  
Prompt Diagnosis

Mucormycosis is a rare but devastating infection. We present a case of fatal disseminated mucormycosis infection in a renal transplant patient. Uncontrolled diabetes mellitus and immunosuppression are the major predisposing factors to infection with Mucorales. Mucorales are angioinvasive and can infect any organ system. Lungs are the predominant site of infection in solid organ transplant recipients. Prompt diagnosis is challenging and influences outcome. Treatment involves a combination of surgical and medical therapies. Amphotericin B remains the cornerstone in the medical management of mucormycosis, although other agents have been used. Newer agents are promising.

scholarly journals An Unusual Source of Sinonasal Disease in an Immunocompromised Patient: A Case Report of the Clinical Presentation, Diagnosis, and Treatment of Acanthamoeba Rhinosinusitis

2020 ◽  
pp. 014556132096893
Author(s):  
David Guirguis ◽  
Lawrence Kashat ◽  
Sara Moradi ◽  
Gregory S. Bonaiuto
Keyword(s):  
Renal Transplant Patient ◽  
Transplant Patient ◽  
Clinical Presentation ◽  
Immunocompromised Patient ◽  
Critical Role ◽  
Diagnosis And Treatment ◽  
Wide Range ◽  
History Of ◽  
Proper Diagnosis ◽  
Immunocompromised State

Chronic nasal crusting is a commonly encountered entity in an otolaryngology office. Progressive, extensive nasal crusting with erosion is relatively unusual, however. We present the case a 58-year-old renal transplant patient with a history of vasculitis and immunosuppression who presents with subjective headache and facial pain, nasal crusting, and isolated left ethmoid sinusitis. She developed extensive intranasal necrosis and underwent multiple endoscopic sinus surgeries with intraoperative biopsies, which played a critical role in her workup and eventual diagnosis of Acanthamoeba rhinosinusitis. Although she endured a difficult course, proper diagnosis and treatment allowed for her recovery over time. The differential diagnosis for intranasal necrosis is often broad. This case highlights the wide range of etiologies to be considered in a patient with extensive nasal crusting and erosion/necrosis, and the importance of thorough diagnostic evaluation in these patients, especially those in an immunocompromised state.

Bk Polyoma Virus Nephropathy In An Immunocompromised Host.

2020 ◽  
Vol 01 ◽  
Author(s):  
Faraz Khan ◽  
Maroun El Khoury ◽  
Fahad Kouli ◽  
Aaron Han
Keyword(s):  
Renal Transplant ◽  
Graft Failure ◽  
Renal Transplant Patient ◽  
Relevant Literature ◽  
Late Complication ◽  
Solid Organ Transplantation ◽  
Immunocompromised Host ◽  
Polyoma Virus ◽  
Solid Organ ◽  
Early Graft

Background: Post-transplant Lymphopoliferative disorders(PTLD) are a well known late complication after solid organ transplantation including renal transplant. Among others, graft failure due to reactivation of BK polyoma virus in the grafted kidney is also a well recognized complication but tends to present early in the first several months after transplant. Case: Here we present the case of PTLD Burkitt's lymphoma(BL-PTLD) in a renal transplant patient who was successfully treated with multiagent chemo-immunotherapy but later developed BK polyoma virus nephropathy(BKVN) with graft failure only after completion of her systemic therapy for lymphoma and 7 years after transplant. Relevant literature is reviewed. Conclusion: In this case, reactivation and progression of BKVN was most likely associated with immunosuppression from chemoimmunotherapy for her BL–PTLD unlike early graft failures associated with BKVN.

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