scholarly journals Primary Amelanotic Malignant Melanoma of the Parotid Gland: A Case Report

2008 ◽  
Vol 36 (6) ◽  
pp. 1435-1439 ◽  
Author(s):  
N Gao ◽  
L-J Li ◽  
Y Li ◽  
L Wang
Keyword(s):  
Case Report ◽  
Malignant Melanoma ◽  
Parotid Gland ◽  
Relevant Literature ◽  
Immunohistochemical Analysis ◽  
Present Case Report ◽  
Clinical Appearance ◽  
Amelanotic Malignant Melanoma ◽  
S 100 ◽  
High Level

Amelanotic malignant melanoma in the oral region is extremely rare and has not previously been reported in the parotid gland. This present case report describes an amelanotic malignant melanoma in the parotid gland, with no other primary lesion detectable. The medical history, pathology and immunohistochemical analysis of the case are described and the relevant literature is reviewed in order to help in the recognition of this uncommon tumour. Amelanotic malignant melanoma is a melanoma subtype with little or no pigmentation and, because of this lack of pigmentation and its wide-ranging clinical appearance, it often defies clinical diagnosis. A high level of vigilance is, therefore, necessary in diagnosing such a tumour in the parotid gland. Where it is suspected, positive expression of S-100 protein and human melanoma black 45 (HMB45) using immunohistochemical analysis can be considered reliable methods of confirming diagnosis.

scholarly journals Metastatic Amelanotic Malignant Melanoma with Unknown Primary - A Case Report

2004 ◽  
Vol 60 (3) ◽  
pp. 295-296 ◽  
Author(s):  
Nikhil Moorchung ◽  
B Mukherjee ◽  
V Srinivas ◽  
H Subramanya
Keyword(s):  
Case Report ◽  
Malignant Melanoma ◽  
Unknown Primary ◽  
Amelanotic Malignant Melanoma

scholarly journals Primary malignant melanoma of the parotid gland: A case report and review of the literature

2020 ◽  
Vol 60 ◽  
pp. 660-663
Author(s):  
Anass Chaouki ◽  
Omar Berrada ◽  
Zouhair Najib ◽  
Youssef oukessou ◽  
Reda Allah Abada ◽  
...  
Keyword(s):  
Case Report ◽  
Malignant Melanoma ◽  
Parotid Gland ◽  
Primary Malignant Melanoma ◽  
Review Of The Literature

scholarly journals Balloon Cell Malignant Melanoma in a Young Female: A Case Report and Review of the Literature

2016 ◽  
Vol 9 (1) ◽  
pp. 262-266 ◽  
Author(s):  
Yui Hattori ◽  
Kazuhiro Sentani ◽  
Takuya Hattori ◽  
Yoshimi Matsuo ◽  
Mikio Kawai ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Lymph Nodes ◽  
Immunohistochemical Analysis ◽  
Histopathological Analysis ◽  
Lumbar Region ◽  
Ki 67 ◽  
Complete Replacement ◽  
Clinical Appearance ◽  
Balloon Cells ◽  
Balloon Cell

Balloon cell malignant melanoma (BCMM) is a very rare malignant melanoma subtype. The clinical appearance of BCMM varies; it may be nodular, ulcerated, polypoid, papillomatous and often non-pigmented. The tumor cells histologically appear large, polygonal or round and contain abundant granular or vacuolated cytoplasm. We herein report the case of a 32-year-old female who presented with a focal eccentric pigmented mass in the left lumbar region of 15 mm in diameter that had been present for several years. She underwent tumor excision. The histopathological analysis showed epithelioid melanocytes with clear cytoplasm. An immunohistochemical analysis revealed that the cells were positive for HMB-45 and S-100 protein and negative for cytokeratin. The balloon cell component stained negative for Fontana-Masson. A month later, the patient underwent excision of the bilateral inguinal lymph nodes and metastatic BCMM was revealed. The lymph node metastases showed the complete replacement of lymph nodes by balloon cells. A diagnosis of BCMM (Breslow depth 10 mm, Clark level V) without ulcer was rendered. Staining with Ki-67 was positive in almost 44% of the balloon cells.

scholarly journals Malignant melanoma of the bladder: A case report

2014 ◽  
Vol 8 (1-2) ◽  
pp. 54 ◽  
Author(s):  
Hamide Sayar ◽  
Seyda Erdogan ◽  
Fulya Adamhasan ◽  
Esma Gurbuz ◽  
Mehmet Fatih İnci
Keyword(s):  
Case Report ◽  
Malignant Melanoma ◽  
Immunohistochemical Staining ◽  
Correct Diagnosis ◽  
Primary Lesion ◽  
Histological Features ◽  
Malignant Melanomas ◽  
Metastatic Lesions ◽  
S 100 ◽  
Hmb 45

Primary malignant melanoma of the bladder is very rare. Rather than being a primary lesion, malignant melanomas of the bladder are more commonly metastatic lesions. The histopathological appearance largely does not differ from that of melanoma at other body sites. It is often difficult to discriminate whether a bladder melanoma is primary or metastatic. Therefore, a careful review of histological features and performing necessary immunohistochemical staining procedures for S-100 protein and HMB-45 are very important in achieving a correct diagnosis. We report a case of hypomelanotic malignant melanoma of the bladder. Despite the variety of therapies available for primary melanomas of the bladder, the prognosis is still poor.

Desmoplastic amelanotic malignant melanoma: A case report.

1988 ◽  
Vol 50 (5) ◽  
pp. 839-842 ◽  
Author(s):  
Yasushi TOMITA ◽  
Taizo KATO ◽  
Okitaka MAIE
Keyword(s):  
Case Report ◽  
Malignant Melanoma ◽  
Amelanotic Malignant Melanoma
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