Comparison of Stress Hormone Response, Interleukin-6 and Anaesthetic Characteristics of Two Anaesthetic Techniques: Volatile Induction and Maintenance of Anaesthesia using Sevoflurane versus Total Intravenous Anaesthesia using Propofol and Remifentanil

2009 ◽  
Vol 37 (6) ◽  
pp. 1760-1771 ◽  
Author(s):  
CH Ihn ◽  
JD Joo ◽  
JW Choi ◽  
DW Kim ◽  
YS Jeon ◽  
...  
Keyword(s):  
Interleukin 6 ◽  
Anaesthetic Techniques ◽  
Total Intravenous Anaesthesia ◽  
Stress Hormone ◽  
Hormone Response ◽  
Intravenous Anaesthesia ◽  
Volatile Induction

scholarly journals Balanced Total Intravenous Anaesthesia and Intraocular Pressure

1981 ◽  
Vol 9 (3) ◽  
pp. 255-259 ◽  
Author(s):  
A. Norbury ◽  
A. D. Rocke ◽  
J. G. Brock-Utne ◽  
R. Mackenzie ◽  
N. Welsh ◽  
...  
Keyword(s):  
Heart Rate ◽  
Intraocular Pressure ◽  
Anaesthetic Techniques ◽  
Systolic Arterial Pressure ◽  
Total Intravenous Anaesthesia ◽  
Physical Status ◽  
Ophthalmic Surgery ◽  
Safe Alternative ◽  
Intravenous Anaesthesia ◽  
Group I

Twenty patients, aged 21 to 48 years and rated ASA physical status I, were studied during ophthalmic surgery. Ten subjects (Group I) received thiopentone, halothane and nitrous oxide in oxygen, and ten (Group II) received total intravenous anaesthesia, using flunitrazepam and ketamine. Ventilation was controlled mechanically with the aid of a muscle relaxant. Both anaesthetic techniques caused a significant decrease in intraocular pressure. After an initial decline in systolic arterial pressure and an increase in heart rate, cardiovascular status was well maintained in the two series. Side effects were uncommon with both techniques. Balanced total intravenous anaesthesia with flunitrazepam, ketamine and relaxant appears to offer a safe alternative to conventional inhalation narcosis for intraocular surgery.

Comparison of two injectable anaesthetic techniques on induction and subsequent anaesthesia in pigs

2021 ◽  
pp. 002367722110298
Author(s):  
Anneli Ryden ◽  
Sheila Fisichella ◽  
Gaetano Perchiazzi ◽  
Görel Nyman
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Anaesthetic Techniques ◽  
Total Intravenous Anaesthesia ◽  
Depth Of Anaesthesia ◽  
Intravenous Anaesthesia ◽  
Physiological Variables ◽  
Arterial Blood ◽  
Nociceptive Stimulus ◽  
Free Induction

Pig experiments often require anaesthesia, and a rapid stress-free induction is desired. Induction drugs may alter the subsequent anaesthesia. Therefore, the aim of the present study was to compare, in pigs, the effects of two different injectable anaesthetic techniques on the induction and on the physiological variables in a subsequent eight hours of total intravenous anaesthesia (TIVA). Twelve domestic castrates (Swedish Landrace/Yorkshire) 27‒31 kg were used. The pigs were randomly assigned to different induction drug combinations of zolazepam–tiletamine and medetomidine intramuscularly (ZTMe) or midazolam, ketamine intramuscularly and fentanyl intravenously (MiKF). Time from injection to unconsciousness was recorded and the ease of endotracheal intubation assessed. The TIVA infusion rate was adjusted according to the response exhibited from the nociceptive stimulus delivered by mechanically clamping the dewclaw. The time from injection to unconsciousness was briefer and intubation was easier in the ZTMe group. Results from the recorded heart rate, cardiac index and arterial blood pressure variables were satisfactorily preserved and cardiovascular function was maintained in both groups. Shivering was not observed in the ZTMe group, but was observed in four of the pigs in the MiKF group. The requirement of TIVA was lower in the ZTMe group. In conclusion, ZTMe had better results than MiKF in areas such as shorter induction time, better intubation scoring results and less adjustment and amount of TIVA required up to six hours of anaesthesia. The results may have been due to a greater depth of anaesthesia achieved with the ZTMe combination at the dose used.

Comparison of Total Intravenous, Balanced Inhalational and Combined Intravenous-Inhalational Anaesthesia for Tympanoplasty, Septorhinoplasty and Adenotonsillectomy

1995 ◽  
Vol 23 (5) ◽  
pp. 574-582 ◽  
Author(s):  
A. A. Van Den Berg ◽  
D. Savva ◽  
N. M. Honjol ◽  
N. V. Rama Prabhu
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Anaesthetic Techniques ◽  
Total Intravenous Anaesthesia ◽  
Intravenous Anaesthesia ◽  
Haemodynamic Stability ◽  
Inhalational Anaesthetic ◽  
Inhalational Anaesthesia ◽  
Intravenous Anaesthetic ◽  
Induction Of Anaesthesia

Two hundred and thirty-five consecutive Saudi patients aged between two and fifty-three years undergoing elective tympanoplasty (n = 32), septorhinoplasty (n = 68) or adenotonsillectomy (n=135) were studied. They were randomized to receive either a total intravenous anaesthetic (10 ears, 23 noses, 44 throats) consisting of propofol for induction of anaesthesia followed by a propofol infusion, a combined intravenous-inhalational anaesthetic (11 ears, 22 noses, 46 throats) consisting of the above with isoflurane in oxygen-enriched air, or a balanced inhalational anaesthetic (11 ears, 23 noses, 45 throats) consisting of thiopentone for induction of anaesthesia and oxygen in nitrous oxide with isoflurane for maintenance. During tympanoplasty, all three anaesthetic techniques produced stable heart rates and arterial pressures. During septorhinoplasty, blood pressure rose in patients who received total intravenous anaesthesia, while combined and balanced techniques produced haemodynamic stability. During adenotonsillectomy, total intravenous anaesthesia produced a rise in both heart rate and blood pressure, the combined technique produced a rise in heart rate alone while balanced anaesthesia produced haemodynamic stability. Postoperatively, vomiting, pain scores and analgesic requirements were similar following all three types of anaesthetic within each surgical site subgroup. Our findings support the choice of balanced inhalational anaesthesia for all three types of ENT surgery and, where cost and facilities permit, total intravenous anaesthesia for tympanoplasty and combined intravenous-inhalational anaesthesia for septorhinoplasty.

Is it time to stop using desflurane?

2020 ◽  
Vol 81 (4) ◽  
pp. 1-2
Author(s):  
Fiona Armstrong ◽  
Joseph Sebastian
Keyword(s):  
Environmental Impact ◽  
Anaesthetic Techniques ◽  
Total Intravenous Anaesthesia ◽  
Intravenous Anaesthesia

Desflurane has a carbon equivalence 20 times greater than sevoflurane. This article discusses alternative anaesthetic techniques, including sevoflurane, xenon, total intravenous anaesthesia and regional techniques, and methods of reducing venting of gases, which might lower the environmental impact of anaesthesia.

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