Life Satisfaction among Kidney Transplant Recipients: Demographic and Biological Factors

2002 ◽  
Vol 12 (4) ◽  
pp. 293-298 ◽  
Author(s):  
Bonnie Siegal ◽  
R. J. Halbert ◽  
M. J. McGuire

Purpose The Transplant Learning Center is a program providing education and support for solid-organ transplant recipients taking cyclosporine (Neoral or Sandimmune). One goal of the program is to improve patients' quality of life, which may be influenced by demographic and biological factors, and in turn influences adherence to prescribed medication regimens. We analyzed the results from the initial survey of enrollees to better understand life satisfaction and to test the validity and reliability of the satisfaction scale used in the program. Method Patients enter the program through self-selection: all enrollees who received a kidney transplant were included in this analysis. Satisfaction was measured using the Life Satisfaction Index, which includes 8 questions about aspects of satisfaction with the patient's life. Associations between the Life Satisfaction Index and demographic factors, comorbid medical conditions, adverse effects of immunosuppressants, and medication compliance were examined. Results All 3676 kidney transplant recipients who completed the initial survey were included. Mean satisfaction scores were highest in persons who were older than 64 years, men, and those who were married. Satsifaction scores were positively correlated with education and income. Mean satisfaction score was significantly lower among persons with medical comorbidities, persons who reported that adverse effects of medications were more frequent, and persons who reported noncompliance with their medication regimen. Conclusion The Life Satisfaction Index is a transplant-specific measure of health-related quality of life that can be used to help detect areas of potential concern in the clinical management of kidney transplant recipients.

2007 ◽  
Vol 39 (4) ◽  
pp. 1126-1129 ◽  
Author(s):  
M.-H. Nourbala ◽  
M.-T. Hollisaaz ◽  
M. Nasiri ◽  
S. Bahaeloo-Horeh ◽  
M. Najafi ◽  
...  

2020 ◽  
Vol 5 (6) ◽  
pp. 264-271
Author(s):  
Ujjwal Dahiya ◽  
Kamli Prakesh ◽  
Sandeep Mahajan ◽  
Nand Kumar

Aim: To assess psychological symptoms, quality of life and adherence to immunosuppressive therapy in kidney transplant recipients. Design: Cross-sectional study was conducted in kidney transplant recipients. Methods: This cross-sectional study included a total of 96 consecutive patients at least 3 months after kidney transplantation from September 2019 to November 2019. Psychological symptoms (anxiety, stress and depression) were assessed using the Depression, Anxiety and Stress Scale. The World Health Organization Quality of Life Instrument was used to assess quality of life in kidney transplant recipients. Adherence to immunosuppressive therapy was assessed by the Morisky Green Levine (MGL) adherence scale. The demographic and clinical details were assessed with a validated self-structured questionnaire. Results: The study included a young adult male population with a mean age of 38.82±10.53 years. The majority of patients reported at least some psychological abnormalities, with mild stress being the most common and presenting in 73% of patients. Importantly, 29% and 21% of patients reported anxiety and depression. Stress was significantly associated with gender, post-transplantation infection and hospitalisation. Anxiety was significantly associated with low family income and post-transplant complication of infection. Psychological symptoms significantly affected the various domains of quality of life of the patients. None of the surveyed patients had low adherence, while 56 (58.3%) had medium adherence to immunosuppressive therapy. Patients with medium adherence to immunosuppressive therapy had significantly lower scores in physical (p=0.01) and social relationship (p= 0.004) domains of quality of life. Conclusion: A significant number of young and stable kidney transplant recipients have presented with psychological symptoms (mainly depression) that affected their quality of life. The presence of psychological symptoms can not only hamper quality of life, but also affect their compliance to drugs. Impact: Psychological health is an important concern after kidney transplantation. Nurses should include assessment of psychological symptoms in their care that would further help in improving quality of life and adherence to drugs in kidney transplant recipients.


2013 ◽  
Vol 27 (4) ◽  
pp. E415-E423 ◽  
Author(s):  
Ingrid B. de Groot ◽  
J. Iraida E. Veen ◽  
Paul J. M. van der Boog ◽  
Sandra van Dijk ◽  
Anne M. Stiggelbout ◽  
...  

2009 ◽  
Vol 23 (5) ◽  
pp. 600-605 ◽  
Author(s):  
Pilar Isla Pera ◽  
Joaquin Moncho Vasallo ◽  
Alberto Torras Rabasa ◽  
Federico Oppenheimer Salinas ◽  
Laureano Fernández Cruz Pérez ◽  
...  

JCI Insight ◽  
2016 ◽  
Vol 1 (8) ◽  
Author(s):  
Maria Lucia L. Madariaga ◽  
Philip J. Spencer ◽  
Kumaran Shanmugarajah ◽  
Kerry A. Crisalli ◽  
David C. Chang ◽  
...  

2021 ◽  
Vol 16 (11) ◽  
pp. 1686-1694
Author(s):  
Tim J. Knobbe ◽  
Daan Kremer ◽  
Michele F. Eisenga ◽  
Marco van Londen ◽  
António W. Gomes-Neto ◽  
...  

Background and objectivesMany kidney transplant recipients suffer from fatigue and poor health-related quality of life. Airflow limitation may be an underappreciated comorbidity among kidney transplant recipients, which could contribute to fatigue and lower health-related quality of life in this population. In this study, we compared the prevalence of airflow limitation between kidney transplant recipients and healthy controls and investigated associations of airflow limitation with fatigue and health-related quality of life in kidney transplant recipients.Design, setting, participants, & measurementsData from the ongoing TransplantLines Biobank and Cohort study were used. Airflow limitation was defined as forced exhaled volume in 1 second less than the fifth percentile of the general population. Fatigue and health-related quality of life were assessed using checklist individual strength 20 revised (CIS20-R) and Short Form-36 (SF-36) questionnaires.ResultsA total of 539 kidney transplant recipients (58% men; mean age 56±13 years) and 244 healthy controls (45% men; mean age 57±10 years) were included. Prevalence of airflow limitation was higher in kidney transplant recipients than in healthy controls (133 [25%] versus 25 [10%]). In multinomial regression models, airflow limitation was independently associated with fatigue severity (odds ratio moderate fatigue, 1.68; 95% confidence interval, 0.92 to 3.09 and odds ratio severe fatigue, 2.51; 95% confidence interval, 1.39 to 4.55; P=0.007) and lower physical health-related quality of life (−0.11 SDs; 95% confidence interval, −0.19 to −0.02; P=0.01) in kidney transplant recipients. In exploratory mediation analyses, fatigue accounted for 79% of the association of airflow limitation with physical health-related quality of life.ConclusionsAirflow limitation is common among kidney transplant recipients. Its occurrence is associated with more than two times higher risk of severe fatigue, and it is associated with lower physical health-related quality of life. Mediation analyses suggest that airflow limitation causes fatigue, which in turn, decreases physical health-related quality of life.Clinical Trial registry name and registration number:TransplantLines: The Transplantation Biobank, NCT03272841PodcastThis article contains a podcast at https://www.asn-online.org/media/podcast/CJASN/2021_11_08_CJN06600521.mp3


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