scholarly journals Transcranial duplex ultrasound monitoring of intracranial arterial stenosis treated with ELUTAX “3” drug-eluting balloon

2020 ◽  
Vol 26 (6) ◽  
pp. 800-804
Author(s):  
Elena Elvira Soler ◽  
Blanca Serrano Serrano ◽  
Nicolás López Hernández ◽  
Natasha Guevara Dalrymple ◽  
Sarai Moliner Castellano ◽  
...  

We report the results of transcranial ultrasound monitoring in three patients with intracranial arterial stenosis of the middle cerebral artery treated with the only drug-eluting balloon certificated for intracranial use in highly symptomatic intracranial arterial stenosis, ELUTAX “3” (AR Baltic Medical). We performed transcranial Doppler ultrasounds 24 h, 72 h, 10 days, 15 days and 30 days after the angioplasty, thereby measuring mean flow velocity (MFV) in the maximum stenosis area in patients with symptomatic steno-occlusive disease of the middle cerebral artery treated with ELUTAX “3”. Two patients were treated during mechanical thrombectomy (MT) due to acute ischemic stroke and one patient was treated on elective basis due to symptomatic pre-occlusive stenosis, with recurrent transient ischemic attacks (TIAs) refractory to medical therapy. In Case 1, the first transcranial Doppler ultrasounds evidenced MFV of 348 cm/s, with progressive MFV reduction until 15 days post-treatment, with MFV of 177 cm/s. In Case 2, 24 h after angioplasty had an MFV of 258 cm/s, decreasing to 103 cm/s at 30 days. Case 3 had an MFV of 436 cm/s before angioplasty that immediately decreased after the procedure to 364 cm/s, with a final MFV of 260 cm/s at 30 days. We have recorded a progressive MFV reduction in intracranial arterial stenosis, with better outcomes in patients treated during MT. In our experience, the use of ELUTAX “3” for the treatment of symptomatic intracranial arterial stenosis achieves a progressive improvement of stenosis, evident in the first weeks, to a higher extent in cases of occlusive thrombosis. More studies are needed to provide more information about this device.

2021 ◽  
Vol 11 (2) ◽  
pp. 437-444
Author(s):  
Yicheng Huang ◽  
Junyan Peng ◽  
Rong Mi ◽  
Zhenxing Yang ◽  
Linquan Zhu ◽  
...  

Ischemic cerebrovascular diseases are important duet to the high incidence, disability, mortality, and recurrence. Intracranial arterial stenosis caused by atherosclerosis is an important pathological basis of ischemic cerebrovascular disease. Therefore, convenient, non-invasive, cheap and accurate screening methods have become the goal of everyone's joint efforts. The purpose of this study was to investigate the value of transcranial Doppler in judging arterial stenosis, and to explore the best cut-off point for assessing the blood flow velocity of middle cerebral artery disease and the compensation of the posterior branch of middle cerebral artery disease. Using retrospective analysis, binomial logistic regression analysis was performed on risk factors related to ischemic cerebrovascular disease. The 60 patients with intracranial stenosis were selected for TCD (Transcranial Color Doppler) and CTA (Computed Tomography Angiography) examinations within one week of onset. CTA was used as the diagnostic criterion to analyze the accuracy of TCD in the diagnosis of intracranial arterial disease. ROC (Receiver Operating Characteristic) curve was used to determine the optimal cutoff point of blood flow velocity for MCA (Middle Cerebral Artery) lesions. TCD has high specificity and sensitivity in the diagnosis of intracranial arterial disease, and it can be widely used in clinic as a simple, convenient and cheap diagnostic method for screening intracranial arterial stenosis.


2017 ◽  
Vol 2 (1) ◽  
pp. 307
Author(s):  
Esdras Ardi Pramudita

Serebral Arteriovenous Malformation (AVM) merupakan suatu kelainan pada formasi pembuluh darah di otak. Keadaan dinding pembuluh darah yang terbentuk pada AVM tidak sebaik dengan pembuluh darah normal sehingga mudah pecah dan menimbulkan masalah intraserebral. TCD merupakan suatu pemeriksaan berbasis ultrasound yang bersifat non invasif, murah dan real time dalam memeriksa kondisi hemodinamik intraserebral dan TCD dapat digunakan untuk menentukan feeder artery pada serebral AVM. Melaporkan dua kasus Serebral AVM selama bulan Juli-September 2016 di RS Panti Rapih Yogyakarta dari kedua kasus didapatkan peningkatan Mean Flow Velocity (MFV) dan penurunan Pulsatility Index (PI) <0,5 pada Right Anterior Cerebral Artery (R-ACA) dari kasus pertama dan Left Middle Cerebral Artery (L-MCA) dari kasus kedua yang menunjukkan bahwa arteri-arteri ini sebagai feeder artery


2020 ◽  
Vol 10 (9) ◽  
pp. 2181-2185
Author(s):  
Mei Wang ◽  
Shihao You ◽  
Lina Mao ◽  
Xianghui He

Objective: The purpose of this experiment is to observe the clinical effect of transcranial ultrasound thrombolytic adjuvant therapy, and to provide clinical results for transcranial ultrasound thrombolytic therapy for atherosclerotic cerebral arterial stenosis. in accordance with. Methods: Collected in the Department of Neurology, Brain Hospital of our hospital within 24 hours after the onset from October 2012 to April 2014, DSA and/or MRA, CTA examination confirmed the existence of middle cerebral artery stenosis and evidence of cerebral atherosclerosis, 100 patients with narrow middle cerebral artery as the diagnostic criteria for cerebral infarction. Results: The positive rates of microemboli in the ultrasound thrombolysis group at 7 days and 14 days were 17.00% and 6.00% significantly lower than those in the drug treatment group at 67.00% and 8.30% (P < 0.05); the 7 days and 14 days of ultrasound thrombolysis treatment group Serum high-sensitivity (P < 0.05), and serum C-reactive protein levels in the ultrasound thrombolytic treatment group were significantly lower than those in the drug treatment group (P < 0.05). Conclusion: Transcranial ultrasound thrombolytic adjuvant drug treatment can significantly promote the recovery of neurological function.


2021 ◽  
pp. 154431672110335
Author(s):  
Vanessa T. Tran ◽  
Anne Moore ◽  
Laligam Sekhar

This report describes a 42-year-old male with a 5-year history of transient ischemic attacks (TIAs), migraines, previous strokes, and symptoms referable to a left middle cerebral artery (MCA) territory event. Computed tomography angiography (CTA) and magnetic resonance angiography (MRA) revealed severe stenoses in the proximal left MCA and proximal left anterior cerebral artery (ACA). Transcranial Doppler ultrasound/Transcranial Doppler imaging (TCD/TCI) and cerebral angiogram confirmed the stenoses with a mean flow velocity (MFV) at the proximal left MCA, with a velocity of 230 cm/s. A Wingspan Stent System stent was placed in the proximal left MCA. Cerebral angiogram and serial TCD examinations performed post stent placement showed a patent left MCA without stenosis and a MFV of 55 cm/s. The left ACA was occluded following proximal left MCA stent placement. This case highlights the usefulness of TCD in the assessment of the MCA and other basal cerebral arteries.


Sign in / Sign up

Export Citation Format

Share Document