A New Approach to Quality Control: Experience in Steroid Receptor Assay

1988 ◽  
Vol 3 (1) ◽  
pp. 69-69
Author(s):  
M. Borsotti ◽  
R. D'Ettole ◽  
G. Messeri ◽  
M. Quercioli ◽  
A. Piffanelli
1988 ◽  
Vol 34 (10) ◽  
pp. 2076-2079
Author(s):  
M Borsotti ◽  
M Quercioli ◽  
R D'Ettole ◽  
A Piffanelli ◽  
G Messeri

Abstract Lyophilized cytosols prepared from calf uterus and human breast tumor tissue are commonly used to assess the reliability of routine steroid receptor assays. However, preanalytical error (sample preparation, storage, homogenization) cannot be detected in this way. Participating laboratories were asked to mail us all their receptor results obtained over a four-month interval, and to include some information about the patients involved (age, menopausal status, nodal status). After verifying the homogeneity of the populations investigated, we computed consensus means for the percentages of positive samples and for their absolute value. Despite the homogeneity of the characteristics of the populations studied, results from some laboratories systematically differed from the consensus mean. This approach to the quality control of steroid receptors allows evaluation of the whole procedure, from sample preparation to analysis, and thus may be helpful as an addition to the usual practice of distribution of cytosols and tissue powders for assay.


2021 ◽  
Vol 13 (11) ◽  
pp. 2069
Author(s):  
M. V. Alba-Fernández ◽  
F. J. Ariza-López ◽  
M. D. Jiménez-Gamero

The usefulness of the parameters (e.g., slope, aspect) derived from a Digital Elevation Model (DEM) is limited by its accuracy. In this paper, a thematic-like quality control (class-based) of aspect and slope classes is proposed. A product can be compared against a reference dataset, which provides the quality requirements to be achieved, by comparing the product proportions of each class with those of the reference set. If a distance between the product proportions and the reference proportions is smaller than a small enough positive tolerance, which is fixed by the user, it will be considered that the degree of similarity between the product and the reference set is acceptable, and hence that its quality meets the requirements. A formal statistical procedure, based on a hypothesis test, is developed and its performance is analyzed using simulated data. It uses the Hellinger distance between the proportions. The application to the slope and aspect is illustrated using data derived from a 2×2 m DEM (reference) and 5×5 m DEM in Allo (province of Navarra, Spain).


2018 ◽  
Vol 8 (5) ◽  
pp. 3360-3365 ◽  
Author(s):  
N. Pekin Alakoc ◽  
A. Apaydin

The purpose of this study is to present a new approach for fuzzy control charts. The procedure is based on the fundamentals of Shewhart control charts and the fuzzy theory. The proposed approach is developed in such a way that the approach can be applied in a wide variety of processes. The main characteristics of the proposed approach are: The type of the fuzzy control charts are not restricted for variables or attributes, and the approach can be easily modified for different processes and types of fuzzy numbers with the evaluation or judgment of decision maker(s). With the aim of presenting the approach procedure in details, the approach is designed for fuzzy c quality control chart and an example of the chart is explained. Moreover, the performance of the fuzzy c chart is investigated and compared with the Shewhart c chart. The results of simulations show that the proposed approach has better performance and can detect the process shifts efficiently.


2017 ◽  
Vol 103 (1) ◽  
pp. 66-77
Author(s):  
Volodymyr Levytskyi

Abstract The basis for the quality control of commodity dimension stone blocks for mining industry is the study of fracturing. The identification of fracturing in rock masses is one of the most important aspects in rock mass modelling. Traditional methods for determination properties of fracturing are difficult and hazardous. This paper describes a new approach of fracturing identification, based on image and range data, which realized by image processing and special software. In this article describes a method using new computer algorithms that allow for automated identification and calculation of fracturing parameters. Different digital filters for image processing and mathematical dependences are analyzed. The digital imaging technique has the potential for being used in real time applications. The purpose of this paper is the accurate and fast mapping of fracturing in some walls of the Bukinsky gabbro deposit.


1998 ◽  
Vol 125 (5) ◽  
pp. 495-498
Author(s):  
Z. V. Kuz'mina ◽  
V. A. Shatskaya ◽  
Z. C. Smirnova

1996 ◽  
Vol 41 (2) ◽  
pp. 131-139 ◽  
Author(s):  
Sylvie Romain ◽  
Frédérique Spyratos ◽  
Jacques Goussard ◽  
Jean-Louis Formento ◽  
Henri Magdelénat ◽  
...  

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