scholarly journals A New Cytosporone Derivative from the Endophytic Fungus Cytospora sp

2014 ◽  
Vol 9 (7) ◽  
pp. 1934578X1400900 ◽  
Author(s):  
Tomoya Takano ◽  
Takuya Koseki ◽  
Hiromasa Koyama ◽  
Yoshihito Shiono
Keyword(s):  
Antimicrobial Activity ◽  
Endophytic Fungus ◽  
2D Nmr ◽  
Ambrosia Beetle ◽  
Oak Wilt ◽  
Tree Disease ◽  
Platypus Quercivorus ◽  
Mass Spectral ◽  
Screening Study ◽  
Raffaelea Quercivora

Japanese oak wilt (JOW) is a tree disease caused by the fungus Raffaelea quercivora, which is vectored by the ambrosia beetle, Platypus quercivorus. In a screening study of the inhibitory active compounds from fungi, a new cytosporone analogue, compound 1, was isolated from the endophytic fungus Cytospora sp. TT-10 isolated from Japanese oak, together with the known compounds, integracin A (2), cytosporones N (3) and A (4). Their structures were determined by extensive 1D– and 2D–NMR spectroscopic and mass spectral analyses. Compound 1 was identified as 4,5-dihydroxy-3-heptylphthalide and named cytosporone E. Compounds 2 and 3 showed antimicrobial activity against Raffaelea quercivora.

scholarly journals Draft Genome Sequence of Raffaelea quercivora JCM 11526, a Japanese Oak Wilt Pathogen Associated with the Platypodid Beetle, Platypus quercivorus

2016 ◽  
Vol 4 (4) ◽  
Author(s):  
Hayato Masuya ◽  
Ri-ichiroh Manabe ◽  
Moriya Ohkuma ◽  
Rikiya Endoh
Keyword(s):  
Genome Sequence ◽  
Draft Genome ◽  
Mass Mortality ◽  
Ambrosia Beetle ◽  
Draft Genome Sequence ◽  
Oak Wilt ◽  
Platypus Quercivorus ◽  
Japanese Oak Wilt ◽  
Raffaelea Quercivora

The Japanese oak wilt pathogen Raffaelea quercivora and the platypodid beetle, Platypus quercivorus , cause serious mass mortality of Quercus spp. in Japan. Here, we present the first draft genome sequence of R. quercivora JCM 11526 to increase our understanding of the mechanism of pathogenicity and symbiosis with the ambrosia beetle.

scholarly journals Metabolites from the Fungus Phoma sp. 7210, Associated with Aizoon Canariense

2010 ◽  
Vol 5 (8) ◽  
pp. 1934578X1000500
Author(s):  
Jingqiu Dai ◽  
Hidayat Hussain ◽  
Siegfried Dräger ◽  
Barbara Schulz ◽  
Tibor Kurtán ◽  
...  
Keyword(s):  
Solid State ◽  
Absolute Configuration ◽  
Endophytic Fungus ◽  
2D Nmr ◽  
Spectroscopic Methods ◽  
Spectral Measurements ◽  
X Ray ◽  
Mass Spectral ◽  
X Ray Crystallography ◽  
Ray Geometry

A new metabolite, 3,16-diketoaphidicolan (1), was isolated together with four known compounds: aphidicolin (2), 17-acetyl-aphidicolin (3), (+)-eupenoxide (4), and phomoxanthone A (5) from the endophytic fungus Phoma sp. The structure of the new compound 1 was determined by spectroscopic methods (mainly extensive 1D and 2D NMR experiments and by mass spectral measurements) and confirmed by X-ray crystallography. Its absolute configuration was assigned by means of the solid-state CD/TDDFT approach comparing the solid-state CD spectrum with the TDDFT-calculated one on the X-ray geometry.

Reducing damage caused by oak wilt disease transmitted by the ambrosia beetle Platypus quercivorus (Coleoptera: Platypodidae) using oak log pile traps

2016 ◽  
Vol 51 (2) ◽  
pp. 267-274
Author(s):  
Shoichi Saito ◽  
Hiroshi Kondoh ◽  
Aya Takahashi ◽  
Mitsuhiro Okada ◽  
Hideo Miguchi
Keyword(s):  
Wilt Disease ◽  
Ambrosia Beetle ◽  
Oak Wilt ◽  
Platypus Quercivorus

scholarly journals Raffaelea quercivora (Japanese oak wilt).

2021 ◽  
Author(s):  
Hayato Masuya
Keyword(s):  
Tree Mortality ◽  
Wood Products ◽  
Oak Forests ◽  
Native Range ◽  
Oak Wilt ◽  
Platypus Quercivorus ◽  
Japanese Oak Wilt ◽  
International Transport ◽  
Geographic Regions ◽  
Raffaelea Quercivora

Abstract Raffaelea quercivora, together with ambrosia beetle Platypus quercivorus as a vector, is the causal agent of Japanese oak wilt. P. quercivorus occurs from south to east Asia, including Japan, and is associated with trees in the Fagaceae family. R. quercivora is considered native to Japan, Taiwan, Indonesia, Thailand and Vietnam. In Japan, Quercus serrata and Q. crispula [Q. mongolica] are particularly susceptible to Japanese oak wilt, with high rates of mortality. Although there have been reports of the co-occurrence of R. quercivora and P. quercivorus outside of Japan, tree mortality caused by this species complex has never been recorded in these cases. R. quercivora is not on an alert list or listed as a regulated pest in any part of its native range. Although R. quercivora/P. quercivorus are not considered invasive, if they were introduced into susceptible oak forests, possibly via international transport of wood products, there is potential for them to cause extensive tree mortality in other geographic regions.

Raffaelea quercivora (Japanese oak wilt).

2021 ◽  
Author(s):  
Hayato Masuya
Keyword(s):  
Tree Mortality ◽  
Wood Products ◽  
Oak Forests ◽  
Native Range ◽  
Oak Wilt ◽  
Platypus Quercivorus ◽  
Japanese Oak Wilt ◽  
International Transport ◽  
Geographic Regions ◽  
Raffaelea Quercivora

Abstract Raffaelea quercivora, together with ambrosia beetle Platypus quercivorus as a vector, is the causal agent of Japanese oak wilt. P. quercivorus occurs from south to east Asia, including Japan, and is associated with trees in the Fagaceae family. R. quercivora is considered native to Japan, Taiwan, Indonesia, Thailand and Vietnam. In Japan, Quercus serrata and Q. crispula [Q. mongolica] are particularly susceptible to Japanese oak wilt, with high rates of mortality. Although there have been reports of the co-occurrence of R. quercivora and P. quercivorus outside of Japan, tree mortality caused by this species complex has never been recorded in these cases. R. quercivora is not on an alert list or listed as a regulated pest in any part of its native range. Although R. quercivora/P. quercivorus are not considered invasive, if they were introduced into susceptible oak forests, possibly via international transport of wood products, there is potential for them to cause extensive tree mortality in other geographic regions.

Lupane Type Triterpene Isolated from the Leaves of Thecacoris Annobonea (Euphorbiaceae)

2013 ◽  
Vol 12 (10) ◽  
pp. 695-701
Author(s):  
Herve Martial Poumale Poumale ◽  
Alphonsine Nkapwa Guedem ◽  
Louis Pergaud Sandjo ◽  
Bonaventure Tchaleu Ngadjui ◽  
Yoshihito Shiono
Keyword(s):  
Antimicrobial Activity ◽  
Root Growth ◽  
Betulinic Acid ◽  
Aristolochic Acid ◽  
2D Nmr ◽  
Aristolochic Acid I

A new lupane type triterpene (1), together with betulinic acid (2), friedelin (3), aristolochic acid I (4), alpinumisoflavone (5) and 4’-O-methylepinumisoflavone (6) have been isolated from the leaves of Thecacoris annobonea. The structure of the new compound was elucidated on the basis of 1 and 2D NMR experiments. The isolated compounds were evaluated for their phytotoxicity and antimicrobial activity. 1 exhibited significant antimicrobial activity at 30 μg/ml and compounds 1, 2, 3, 4, 5 and 6 inhibited root growth lettuce at 100 μg/ml. 

Synthesis, SAR, In-Silico appraisal and Anti-Microbial Study of substituted 2-aminobenzothiazoles derivatives

2019 ◽  
Vol 15 ◽  
Author(s):  
Devidas G. Anuse ◽  
Suraj N. Mali ◽  
Bapu R. Thorat ◽  
Ramesh S. Yamgar ◽  
Hemchandra K. Chaudhari
Keyword(s):  
Antimicrobial Activity ◽  
In Silico ◽  
Docking Study ◽  
Moderate Activity ◽  
Molecular Docking Study ◽  
Mass Spectral ◽  
Gram Positive Bacteria ◽  
Ft Ir ◽  
In Silico Molecular Docking

Background: Antimicrobial resistance is major global health problem, which is being rapidly deteriorating the quality of human health. Series of substituted N-(benzo[d]thiazol-2-yl)-2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)acetamide (3a-j) were synthesized from substituted N-(benzo[d]thiazol-2-yl)-2-chloroacetamide/bromopropanamide (2a-j) and 6-fluoro-3-(piperidin-4-yl)benzo[d]isoxazole (2) and further evaluated for their docking properties and antimicrobial activity. Methods: All synthesized compounds were characterized by FT-IR, NMR and Mass spectral analysis. All compounds were allowed to dock against different antimicrobial targets having PDB ID: 1D7U and against common antifungal target having PDB ID: 1EA1. Results: The compounds 3d and 3h were showed good activity against Methicillin-resistant Staphylococcus aureus (MRSA, resistance Gram-positive bacteria). All synthesized compounds showed good to moderate activity against selected bacterial and fungal microbial strains. If we compared the actual in-vitro antimicrobial activity and in-silico molecular docking study, we found that molecules 3i and 3h were more potent than the others. Conclusion: Our current study would definitely pave the new way towards designing and synthesis of more potent 2-aminobenzothiazoles derivatives.

scholarly journals Green Synthetic Protocol for (E)-1-Aryl-3-(2-morpholinoquinolin- 3-yl)prop-2-en-1-ones and Their Antimicrobial Activity

2019 ◽  
Vol 31 (9) ◽  
pp. 1895-1898
Author(s):  
Relangi Siva Subrahmanyam ◽  
Venkateswara Rao Anna
Keyword(s):  
Antimicrobial Activity ◽  
Spectral Data ◽  
1H Nmr ◽  
13C Nmr ◽  
Mass Spectral Data ◽  
In Vitro Antimicrobial Activity ◽  
Mass Spectral ◽  
Fungal Organisms

We report here an easy, efficient and green synthetic protocol for the (E)-1-aryl-3-(2-morpholinoquinolin-3-yl)prop-2-en-1-ones by the Claisen-Schmidt condensation of 2-morpholinoquinoline-3-carbaldehyde and different substituted acetophenones by using 1-butyl-3-methylimidazolium tetrafluoroborate (Bmim)BF4. The compounds were characterized by using 1H NMR, 13C NMR and mass spectral data and screened there in vitro antimicrobial activity against different bacterial and fungal organisms.

Sign in / Sign up

Export Citation Format

Share Document