scholarly journals Two New Steroidal Saponins from Solanum procumbens

2018 ◽  
Vol 13 (10) ◽  
pp. 1934578X1801301
Author(s):  
Truong Thi Thu Hien ◽  
Hoang Anh Tuan ◽  
Do Phuong Huong ◽  
Hoang Van Luong ◽  
Ngo Thi Tuyet Mai ◽  
...  
Keyword(s):  
Cell Line ◽  
Functional Groups ◽  
Hepg2 Cell ◽  
Nmr Spectra ◽  
Hepg2 Cell Line ◽  
Steroidal Saponins ◽  
Esi Ms ◽  
Chemical Structures ◽  
Aerial Parts ◽  
Oxidative Breakdown

Two new steroidal saponins, solaprocumosides A (1) and B (2), and a known compound paniculonin B (3) were isolated from the aerial parts of Solanum procumbens. Their chemical structures were determined by analysis of HR-ESI-MS and NMR spectra. Compound 1 had ketone functional groups at C-16 and C-22 of sterol skeleton which is rarely found in nature. Meanwhile, compound 2 could be form by oxidative breakdown C-20/C-22 bonding of a furostane-type saponin. Compounds 1–3 showed weak cytotoxicity against HepG2 cell line with IC50 values of 55.7 ± 1.5, 48.1 ± 2.2, and 78.3 ± 2.4 μM, respectively.

scholarly journals Metformin attenuates hypoxia‑induced resistance to cisplatin in the HepG2 cell line

2018 ◽  
Author(s):  
Hiromasa Fujita ◽  
Katsumi Hirose ◽  
Mariko Sato ◽  
Ichitaro Fujioka ◽  
Tamaki Fujita ◽  
...  
Keyword(s):  
Cell Line ◽  
Hepg2 Cell ◽  
Induced Resistance ◽  
Hepg2 Cell Line

scholarly journals New Truxinic and Truxillic Acid Sucrose Diesters From the Leaves of Trigonostemon honbaensis

2021 ◽  
Vol 16 (2) ◽  
pp. 1934578X2199914
Author(s):  
Ninh Khac Ban ◽  
Bui Huu Tai ◽  
Vu Kim Thu ◽  
Phan Van Kiem
Keyword(s):  
Nmr Spectra ◽  
Raw264.7 Cells ◽  
No Production ◽  
Inhibitory Effects ◽  
Esi Ms ◽  
Chemical Structures ◽  
Extensive Analysis ◽  
Truxillic Acid

A new δ-truxinic acid sucrose diester and a new ε-truxillic acid sucrose diester (named trigohonbanosides E and F) were isolated from the leaves of Trigonostemon honbaensis. Their chemical structures were determined by extensive analysis of their HR-ESI-MS and NMR spectra. At a concentration of 20 µM, trigohonbanosides E and F exhibited weak inhibitory effects on NO production in LPS-activated RAW264.7 cells with inhibitory percentages of 22.7% ± 1.1% and 18.5% ± 1.4%, respectively.

Preliminary screening of some traditional Zulu medicinal plants for antineoplastic activities versus the HepG2 cell line

2000 ◽  
Vol 14 (7) ◽  
pp. 534-537 ◽  
Author(s):  
A. R. Opoku ◽  
M. Geheeb-Keller ◽  
J. Lin ◽  
S. E. Terblanche ◽  
A. Hutchings ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Cell Line ◽  
Hepg2 Cell ◽  
Hepg2 Cell Line ◽  
Preliminary Screening

scholarly journals Isolation and identification of heterogenic subpopulation from the HepG2 cell line by Rhodamine123 extrusion assay

2008 ◽  
Vol 16 (9) ◽  
pp. 941
Author(s):  
Nian-Song Qian ◽  
Ren Li ◽  
Heng-Chao Yu ◽  
Yun-Xin Cao ◽  
Fu-Qin Zhang ◽  
...  
Keyword(s):  
Cell Line ◽  
Hepg2 Cell ◽  
Hepg2 Cell Line ◽  
Isolation And Identification

scholarly journals Atomic force microscopy correlates antimetastatic potentials of HepG2 cell line with its redox/energy status: effects of curcumin and Khaya senegalensis

2017 ◽  
Vol 15 (3) ◽  
pp. 214-230 ◽  
Author(s):  
Jeremiah Olorunjuwon Olugbami ◽  
Robert Damoiseaux ◽  
Bryan France ◽  
Michael A. Gbadegesin ◽  
Adam Z. Stieg ◽  
...  
Keyword(s):  
Atomic Force Microscopy ◽  
Cell Line ◽  
Hepg2 Cell ◽  
Hepg2 Cell Line ◽  
Energy Status ◽  
Force Microscopy ◽  
Atomic Force ◽  
Khaya Senegalensis

Effects of imidacloprid on viability and increase of reactive oxygen and nitrogen species in HepG2 cell line

2021 ◽  
pp. 1-33
Author(s):  
Anilda Rufino de Jesus Santos Guimarães ◽  
Paulo Francisco Veiga Bizerra ◽  
Camila Araújo Miranda ◽  
Fábio Erminio Mingatto
Keyword(s):  
Cell Line ◽  
Hepg2 Cell ◽  
Reactive Oxygen ◽  
Nitrogen Species ◽  
Hepg2 Cell Line

Toxicity and metabolism of deoxynivalenol in human hepatoma (HepG2) cell line

2018 ◽  
Vol 295 ◽  
pp. S146-S147
Author(s):  
L. Radko ◽  
A. Tkaczyk ◽  
P. Jedziniak ◽  
S. Stypuła-Trębas ◽  
A. Posyniak
Keyword(s):  
Cell Line ◽  
Hepg2 Cell ◽  
Human Hepatoma ◽  
Hepg2 Cell Line ◽  
Hepatoma Hepg2
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