scholarly journals Chemical Constituents of Phoebe poilanei and Their Cytotoxic Activity

2019 ◽  
Vol 14 (5) ◽  
pp. 1934578X1985096
Author(s):  
Nguyen Thi Viet Thanh ◽  
Tran Thi Minh ◽  
Dinh Thi Thu Hien ◽  
Ho Duc Cuong ◽  
Yohan Seo ◽  
...  
Keyword(s):  
Nuclear Magnetic Resonance ◽  
High Resolution ◽  
Cytotoxic Activity ◽  
Spectral Data ◽  
Chemical Constituents ◽  
Flavonol Glycosides ◽  
Ionization Mass ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Chemical Structures

Two new flavonol glycosides, rhamnocitrin 3- O-α-L-rhamnopyranosyl-(1→6)-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside (1) and quercetin 3- O-6- Z- p-coumaroyl-β-D-glucopyranosyl-(1→2)-α-L-rhamnopyranoside (2), along with 3 flavonol glycosides, isoquercitrin (3), rutin (4), and quercetin 3- O-α-L-rhamnopyranosyl-(1→6)-β-D-galactopyranoside (5), and two known sesquiterpenes, alismol (6) and spathulenol (7), were isolated from the leaves of Phoebe poilanei Kosterm. Their chemical structures were elucidated by analyses of their high-resolution electrospray ionization mass spectral data and nuclear magnetic resonance spectral data and comparison with those reported in the literature. Two sesquiterpenes 6 and 7 were found to exhibit moderate cytotoxic activity with IC50 values ranging from 21.6 to 29.8 µM.

scholarly journals TERPENOIDS FROM THE LEAVES AND STEMS OF DYSOXYLUM TPONGENSE

2019 ◽  
Vol 57 (2) ◽  
pp. 139
Author(s):  
Pham Ngoc Khanh ◽  
Bui Huu Tai ◽  
Tran Thu Huong ◽  
To Dao Cuong ◽  
Young Ho Kim ◽  
...  
Keyword(s):  
Spectral Data ◽  
Chemical Constituents ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Chemical Structures

Study on chemical constituents from the leaves and stems of Dysoxylum tpongense Pierre resulted in the isolation of six known compounds (1–6). The chemical structures of isolated compounds were identified as cabraleahydroxylactone (1), cabraleahydroxylactone-3-acetate (2), (+) spathulenol (3), b-sitosterol (4), stigmasterol (5), and stigmast-4-en-3-one (6) by comparison of the physicochemical, interpretation of NMR and mass spectral data with that reported in the literature.

scholarly journals Microbial Glycosylation of Phenanthrene and Bibenzyls by Mucor hiemalis

2020 ◽  
Vol 15 (11) ◽  
pp. 1934578X2097450
Author(s):  
Bomi Nam ◽  
Ah-Reum Han ◽  
Ik-Soo Lee
Keyword(s):  
Nuclear Magnetic Resonance ◽  
High Resolution ◽  
Microbial Transformation ◽  
Hydroxyl Group ◽  
Ionization Mass ◽  
Mass Spectral Data ◽  
Mucor Hiemalis ◽  
Mass Spectral ◽  
Nuclear Magnetic Resonance Spectra ◽  
Microbial Glycosylation

Microbial transformation of denthyrsinin (1), gigantol (2), and batatasin III (3), the major constituents of Dendrobium species (Orchidaceae), was performed using the filamentous fungus Mucor hiemalis KCTC 26779. Three glycosylated metabolites were obtained in the biotransformation of 1-3, and their structures were identified as denthyrsinin-6- O-β-d-glucoside (4), gigantol-5- O-β-d-glucoside (5), and batatasin III-3- O-β-d-glucoside (6) by analyzing 1-dimensional and 2-dimensional-nuclear magnetic resonance spectra, as well as high-resolution electrospray ionization mass spectral data. Among them, metabolite 4 has not been previously reported. Mucor hiemalis was revealed to catalyze enzymatically glucosylation of the hydroxyl group of phenanthrenes and bibenzyls. This research provides an efficient approach for the glycosylation of phenanthrenes and bibenzyls and can expand the library of available phenanthrene and bibenzyl derivatives for further biological evaluations.

scholarly journals Four New Acyclic Diterpenes From Siegesbeckia orientalis

2021 ◽  
Vol 16 (11) ◽  
pp. 1934578X2110561
Author(s):  
Do Thi Trang ◽  
Phan Thi Thanh Huong ◽  
Nguyen Thi Cuc ◽  
Duong Thi Dung ◽  
Bui Thi Thu Trang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
High Resolution ◽  
Xanthine Oxidase ◽  
Ionization Mass ◽  
Oxidative Reaction ◽  
Chemical Structures ◽  
Aerial Parts ◽  
Extensive Analysis ◽  
Siegesbeckia Orientalis

Four new acyclic diterpenes, siegetalises A-D (1-4), were isolated from the aerial parts of Siegesbeckia orientalis. Their chemical structures were elucidated by extensive analysis of high-resolution electrospray ionization mass spectrometry and nuclear magnetic resonance spectral data. The effects of the isolated compounds on the activity of xanthine oxidase were evaluated by the oxidative reaction with xanthine as a substrate. At a concentration of 50 µM, compounds 1-4 exhibited xanthine oxidase inhibitory activity at levels of 13.59% ± 0.51%, 19.64% ± 1.54%, 17.45% ± 1.26%, and 21.36% ± 1.40%, respectively.

scholarly journals FLAVONOIDS FROM FLOWERS OF AMESIODENDRON CHINENSE (SAPINDACEAE)

2020 ◽  
Vol 58 (6) ◽  
pp. 676
Author(s):  
Ho Van Ban ◽  
Trinh Thi Thanh Van ◽  
Vu Van Chien ◽  
Nguyen Thi Hue ◽  
Pham Thi Hang ◽  
...  
Keyword(s):  
Spectral Data ◽  
Physicochemical Parameters ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Chemical Structures

From the flowers of Amensiodendron Chinese (Merr.) Hu, six known flavonoids, (-)-catechin (1), (-)-epi-catechin (2), chrysoeriol (3), quercetin-3-O-β-D-glucopyranoside (4), astragalin (5) and kaempferide-3-O-β-D-glucopyranoside (6) were isolated. Their chemical structures were elucidated by analysis of the physicochemical parameters, the NMR and mass spectral data, and comparison with those reported in the literatures.

scholarly journals Araliachinoside A: A New Triterpene Glycoside From Aralia chinensis Leaves

2020 ◽  
Vol 15 (9) ◽  
pp. 1934578X2095275
Author(s):  
Pham Hai Yen ◽  
Nguyen Thi Cuc ◽  
Phan Thi Thanh Huong ◽  
Nguyen Xuan Nhiem ◽  
Nguyen Thi Hoai ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
High Resolution ◽  
Inhibitory Concentration ◽  
In Vitro Assay ◽  
Ionization Mass ◽  
Vitro Assay ◽  
Chemical Structures ◽  
Hepg2 Cell Lines

From the leaves of Aralia chinensis, 3 oleanane-type triterpene glycosides have been isolated, including 1 new glycoside, 3β,23 -dihydroxyolean-12-ene-28-oic acid 3 -O-β-d-glucopyranosyl-(1→3)- α-l-arabinopyranosyl-(1→3)-β-d-glucuronopyranoside 28 -O-β-d-glucopyranosyl ester (named as araliachinoside A, 1), and 2 known ones, 3β,23 -dihydroxyolean-12-ene-28-oic acid 3 -O-α-l-arabinopyranosyl-(1→3)- β-d-glucuronopyranoside 28 -O-β-d-glucopyronosyl ester (2) and 3β-hydroxyolean-12-ene-28-oic acid 3 -O-β-d-glucurono pyranoside 28 -O-β-d-glucopyronosyl ester (3). Their chemical structures were elucidated by using a combination of high-resolution electrospray ionization-mass spectrometry, 1-dimensional and 2-dimensional nuclear magnetic resonance spectral data, and by comparison with previous literature. Compounds 1-3 displayed cytotoxic activity toward KB and HepG2 cell lines with half-maximal inhibitory concentration values ranging from 8.1 ± 0.1 to 15.7 ± 0.3 µM in in vitro assay.

scholarly journals N-[2-(1H-Indol-3-yl)ethyl]-2-(4-isobutylphenyl)propanamide

Molbank ◽  
10.3390/m1031 ◽  
2018 ◽  
Vol 2018 (4) ◽  
pp. M1031
Author(s):  
Stanimir Manolov ◽  
Iliyan Ivanov ◽  
Yulian Voynikov
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Spectral Data ◽  
1H Nmr ◽  
13C Nmr ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Nuclear Magnetic

The compound in the title was prepared by reaction between tryptamine and ibuprofen using N,N′-dicyclohexylcarbodiimide as a “dehydrating” reagent. The structure of the newly synthesized compound was determined by nuclear magnetic resonance (NMR) (1H-NMR and 13C-NMR), UV, IR, and mass spectral data.

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