Primary histiocytic sarcoma in the brain with renal metastasis causing internal ophthalmoparesis and external ophthalmoplegia in a Maine Coon cat

Case summary An 11-year-old neutered male Maine Coon cat was presented for investigation of anisocoria and depression. Neurological examination was consistent with a lesion at the level of the middle cranial fossa, and biochemistry was indicative of moderate renal functional impairment. MRI of the brain identified an extra-axial mass lesion at the level of the middle cranial fossa, T2-weighted hyperintense and strongly homogeneously contrast enhancing with dural tail. The cat was euthanased after 6 weeks of palliative treatment with corticosteroids. Histopathology and immunohistochemistry of the brain, the intra-cranial mass and the renal masses found on necropsy were consistent with histiocytic sarcoma. Relevance and novel information Central nervous system histiocytic sarcoma is a rare finding in cats. This original case report describes the neurological presentation, novel MRI characteristics and pathological findings of suspected primary histiocytic sarcoma affecting the brain with renal metastasis in a cat.

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Clinical, MRI, and Histopathological Features of Hypothalamic Neuronal Hamartoma in a Young Vizsla

Journal of the American Animal Hospital Association ◽

10.5326/jaaha-ms-7083 ◽

2021 ◽

Author(s):

Leonardo Bibbiani ◽

Sara Canal ◽

Daiana Marabese ◽

Maria T. Mandara ◽

Greta Foiani ◽

...

Keyword(s):

Congenital Malformations ◽

Histopathological Examination ◽

Middle Cranial Fossa ◽

Clinical Imaging ◽

First Report ◽

Histopathological Features ◽

Neurological Signs ◽

Cranial Fossa ◽

The Brain ◽

Clinical Mri

ABSTRACT Human hypothalamic neuronal hamartomas are rare, nonprogressive, congenital malformations of the hypothalamus that do not expand or metastasize to other locations. A 1 yr old female vizsla was presented for progressive intracranial multifocal neurological signs already present since adoption at 3 mo of age. MRI of the brain showed an ill-defined, intra-axial, space-occupying, nonenhancing lesion located in the ventral middle cranial fossa. Histopathological examination was consistent with hypothalamic neuronal hamartoma. This is the first report describing clinical, imaging, and histopathological features of a hypothalamic neuronal hamartoma in a dog. These findings are compared with the human counterparts.

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OTITIC EPIDURAL ABSCESS IN THE MIDDLE CRANIAL FOSSA ASSOCIATED WITH ABSCESS OF THE TEMPORAL LOBE OF THE BRAIN

The American Journal of the Medical Sciences ◽

10.1097/00000441-189711000-00004 ◽

1897 ◽

Vol 114 (5) ◽

pp. 546-548

Author(s):

Charles H. Burnett

Keyword(s):

Temporal Lobe ◽

Epidural Abscess ◽

Middle Cranial Fossa ◽

Cranial Fossa ◽

The Brain

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Multiple Intracranial Epidermoids located in the Brain Stem and the Middle Cranial Fossa

Neurologia medico-chirurgica ◽

10.2176/nmc.25.393 ◽

1985 ◽

Vol 25 (5) ◽

pp. 393-397 ◽

Cited By ~ 17

Author(s):

Takeki OGAWA ◽

Hiroaki SEKINO ◽

Takaharu FUSE ◽

Norio NAKAMURA

Keyword(s):

Brain Stem ◽

Middle Cranial Fossa ◽

Cranial Fossa ◽

The Brain

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A 6-YEAR-OLD GIRL WITH AN EXTRA-AXIAL MASS IN THE MIDDLE CRANIAL FOSSA

Brain Pathology ◽

10.1111/j.1750-3639.2009.00348.x ◽

2010 ◽

Vol 20 (1) ◽

pp. 269-272 ◽

Cited By ~ 3

Author(s):

Kenta Masui ◽

Satoshi O. Suzuki ◽

Akira Kondo ◽

Toru Iwaki

Keyword(s):

Middle Cranial Fossa ◽

Axial Mass ◽

Cranial Fossa

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Aneurysmal bone cyst: а case report

Russian journal of neurosurgery ◽

10.17650/1683-3295-2018-20-4-52-60 ◽

2019 ◽

Vol 20 (4) ◽

pp. 52-60

Author(s):

Sh. A. Aul ◽

A. G. Bobylev ◽

T. M. Shogunbenkov ◽

А. M. Gazeev ◽

E. A. Osipova ◽

...

Keyword(s):

Facial Nerve ◽

Temporal Bone ◽

Aneurysmal Bone Cyst ◽

Bone Cyst ◽

Middle Cranial Fossa ◽

Temporal Region ◽

Left Temporal Lobe ◽

Nerve Paresis ◽

Cranial Fossa ◽

The Brain

The study objective is to describe a clinical case of intracranial aneurysmal bone cyst in a 9-year-old patient with peripheral facial nerve paresis on the left.Materials and methods. In a 9-year-old patient with facial asymmetry and pain syndrome on the results of magnetic resonance imaging of the brain with contrast in the upper edge of the left temporal bone pyramid revealed inhomogeneous encapsulated lesion with the level of media separation in the structure, high-intensity zones on T1and T2-weighted images, additional intracranial lesion in the left temporal region. Multispiral computer tomography of the brain revealed a cystic-solid lesion with clear contours, causing destruction of the pyramid of the left temporal bone. Lesion spreads to the middle cranial fossa with compression of the basal parts of the left temporal lobe. The diagnosis was made: neoplasm of the left temporal bone (possibly primary cholesteatoma) with destruction of the pyramid and petrosal part of the temporal bone and clivus with suppuration and formation of abscess of the left temporal lobe. Left facial nerve paresis. Osteo-plastic trepanation of the skull in the left temporal region, microsurgical removal of the tumor of the base of the middle cranial fossa on the left and plastic of the skull base defect with abdominal fat were performed.Results. The postoperative period was uneventful. The patient complained of moderate headaches in the area of operative access. The wound healed by primary tension. Positive dynamics in neurological status in the form of regression of left facial nerve paresis was noted. Based on the data of morphological and immunohistochemical studies, an aneurysmal bone cyst was diagnosed.Conclusion. The method of choice in the treatment of an aneurysmal bone cyst of the skull base is the en block removal. In case of impossibility of carrying out radical operation radiotherapy and embolization of the vessels feeding a cyst can be used, however convincing researches about their efficiency in such cases are not published. Aneurysmal bone cyst is uncommon, and to differentiate it from chondroblastoma, teleangiectatic osteosarcoma and giant cell tumors is rather difficult, therefore, it is necessary to increase the level of knowledge about this nosology.

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A STUDY ON PATTERN OF INTRACRANIAL INJURIES IN CASES OF FATAL HEAD INJURY

10.36106/ijsr/3436301 ◽

2021 ◽

pp. 56-57

Author(s):

Dharmendra Kumar ◽

Ritu Ritu ◽

Sohan Prasad Choudhary ◽

Debarshi Jana

Keyword(s):

Head Injuries ◽

Skull Fracture ◽

Middle Cranial Fossa ◽

Subdural Hemorrhage ◽

Trauma Patients ◽

Fall From Height ◽

Comminuted Fractures ◽

Cranial Fossa ◽

Dissection Technique ◽

The Brain

Head injuries are the most common cause of death in trauma patients throughout the world. These injuries occur due to many causes most common of them being road trafc accidents, followed by fall, assault, etc. The dissection technique of scalp, skull and dura was in accordance with the procedures suggested by Gresham GA and Turner AF and the brain dissection as suggested by Ludwig J. Among the 42 cases, highest number of cases was between the age of 51-60 years with 12 cases (28.6%) and the lowest < 20 years with 4 cases (9.5%). The highest number of cases were seen among the upper middle class with 19(45.2%). There were 30 (71.4%) cases of road trafc accidents and the remaining 12 (28.6%) were case of fall (fall from height, fall of objects etc). Among the cases with skull fracture 23.8% (10) had linear fractures, 11.9% (5) had comminuted fracture, 2.4% (1) had diastatic fracture and others (61.9%) had no fractures. Subdural hemorrhage was the commonest (n=34) intracranial injury observed. Highest number of fractures were present in the middle cranial fossa (n=16) among them 11 was linear fractures and 5 were comminuted fractures.

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Severe Constricted Head – An Extreme Form Of Crouzon Syndrome Posing Challenging Fronto-Orbital Advancement : Case Reports

Jurnal Rekonstruksi dan Estetik ◽

10.20473/jre.v4i2.28222 ◽

2021 ◽

Vol 4 (2) ◽

pp. 71

Author(s):

Ciptomurti Lupitasari ◽

Lobredia Zarasade ◽

Magda Hutagalung

Keyword(s):

Acanthosis Nigricans ◽

Case Reports ◽

Middle Cranial Fossa ◽

Severe Form ◽

Crouzon Syndrome ◽

Excessive Bleeding ◽

Disease Spectrum ◽

Lambdoid Synostosis ◽

Cranial Fossa ◽

The Brain

Background : Constricted head or cloverleaf deformity in Crouzon syndrome is a severe form of the syndrome involving trilobed coronal and lambdoid synostosis. Crouzon syndrome with acanthosis nigricans is distinct from the classic Crouzon syndrome, characterized by thick and dark skin in body folds. The major problems resulting from constricted head are related to craniostenosis, orbitostenosis developing from abnormalities of the skull base associated with progressive rise in intracranial and intraorbital pressures which could progress to hydrocephalus and cerebellar herniation. Case: Two cases with severe Crouzon syndrome were reported. The first was a five month old girl associated with acanthosis nigricans and the other was a sixteen month old boy, both whose phenotypic expressions were at the extreme severe end of the disease spectrum. On examination there was serious corneal exposure, visual loss, severely narrow head, midface hypoplasia, and beaked nose. CT scan showed typical cloverleaf skull, expanded middle cranial fossa, foreshortened anterior and posterior fossae and honeycomb appearance in the occiput involving pansutural synostosis and extensive copper beaten deformity from the high intracranial pressure . Both were complicated with hydrocephalus requiring ventriculoperitoneal shunt. This required an arduous effort in releasing the brain from the multiply punctured calvaria, avoiding excessive dural tear and bleeding and ultimately preserving the brain. Excessive bleeding was also caused by the raised ICP. Both patients are planned to undergo occipital expansion three months later. Conclusion: Severely constricted head in Crouzon syndrome is an extreme manifestation and late stage of the syndrome which not only will result in irreversible complication but will require meticulous surgical technique.

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Ενδοσκοπική ανατομία της περιεφιππιακής χώρας του εγκεφάλου

10.12681/eadd/42475 ◽

2014 ◽

Author(s):

Ανδρέας Μπαϊρακτάρης

Keyword(s):

Pituitary Gland ◽

Middle Cranial Fossa ◽

Endoscopic Technique ◽

Lower Mortality ◽

Less Invasive ◽

Rigid Endoscope ◽

Cranial Fossa ◽

Base Of The Skull ◽

Invasive Techniques ◽

The Brain

Introduction: Modern Neurosurgery requires implementing less invasive techniques, with greater efficiency and lower mortality. The endoscopic technique is an evolution of Neurosurgery in this direction. The parasellar area is a region of the brain where the endoscopic technique may be preferable. Aim: Study the anatomy of parasellar area with the endoscopic technique. Material - Methods: In specially prepared dead bodies with special silicone pigments, parasellar area was studied through the rigid endoscope of Aesculap. In eight (8) bodies was applied the fronto - temporal Key hole endoscopic access and to other eight (8), the endoscopic transnasal transphenoidal technique. Results / Conclusions: The anatomy of the middle cranial fossa revealed adequately with both endoscopic approaches. The transnasal transphenoidal technique is accessed choice for the treatment of pathology in the pituitary gland while fronto-temporal technique is most appropriate for the pathology of the base of the skull, the supra- and para- sellar area.

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