scholarly journals Dedifferentiated liposarcoma with abrupt transition of low-grade and high-grade dedifferentiation: A rare case report

2021 ◽  
Vol 35 ◽  
pp. 205873842110485
Author(s):  
Yang Wen ◽  
Xianglei He ◽  
Ming Zhao
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Dedifferentiated Liposarcoma ◽  
Low Grade ◽  
High Grade ◽  
Sharp Transition ◽  
Abrupt Transition ◽  
Rare Case Report ◽  
Histological Heterogeneity ◽  
Histological Morphology

Dedifferentiated liposarcoma is a unique subtype of liposarcoma, which has obvious histological heterogeneity. In affected patients, the condition typically manifests as the dedifferentiation of high-grade histological morphology, but it may also manifest as the dedifferentiation of low-grade histological morphology. In some cases, unique histological or immunophenotypic characteristics are observed. We describe, herein, a rare case of dedifferentiated liposarcoma, in which the high-grade and low-grade dedifferentiated components coexisted with a relatively sharp transition in pathology.

scholarly journals Dedifferentiated liposarcoma with abrupt transition of low-grade and high-grade dedifferentiated components: A case report

2021 ◽  
Author(s):  
YANG WEN ◽  
XIANGLEI HE ◽  
MING ZHAO
Keyword(s):  
Abdominal Mass ◽  
Dedifferentiated Liposarcoma ◽  
Fish Analysis ◽  
Low Grade ◽  
High Grade ◽  
Sharp Transition ◽  
Mdm2 Gene ◽  
Magnetic Resonance Imaging Mri ◽  
Histological Heterogeneity ◽  
Histological Morphology

Abstract BackgroundDedifferentiated liposarcoma (DDLPS) is a unique subtype of liposarcoma, which has obvious histological heterogeneity. In affected patients, the condition typically manifests as the dedifferentiation of high-grade histological morphology, but it may also manifest as the dedifferentiation of low-grade histological morphology. In some cases, unique histological or immunophenotypic characteristics are observed. We describe, herein, a rare case of dedifferentiated liposarcoma, in which the high-grade and low-grade dedifferentiated components coexisted with a relatively sharp transition in pathology.Case presentationA 69-year-old woman with severe abdominal pain lasting for 1 hour presented to our hospital. Physical examination revealed a mobile large left abdominal mass, Magnetic resonance imaging (MRI) scan showed a huge mass with typical fat components and the non-fatty nodule in the left retroperitoneal cavity. After laparotomy, histologic analysis of the specimens could find the atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDLPS) and DDLPS components. Fluorescence in situ hybridization (FISH) analysis suggested the presence of MDM2 gene amplification. These findings supported a diagnosis of DDLPS.ConclusionIn our case, the high-grade and low-grade dedifferentiated components coexisted with a relatively sharp transition in pathology. We hypothesize that low-grade dedifferentiation may be a precursor to high-grade dedifferentiation. MRI images cannot distinguish the two components.

scholarly journals Dedifferentiated Liposarcoma with Abrupt Transition of Low-Grade and High-Grade Dedifferentiated Components ：A Case Report

2020 ◽  
Author(s):  
YANG WEN ◽  
XIANGLEI HE ◽  
MING ZHAO
Keyword(s):  
Abdominal Mass ◽  
Dedifferentiated Liposarcoma ◽  
Fish Analysis ◽  
Low Grade ◽  
High Grade ◽  
Sharp Transition ◽  
Mdm2 Gene ◽  
Magnetic Resonance Imaging Mri ◽  
Histological Heterogeneity ◽  
Histological Morphology

Abstract Background: Dedifferentiated liposarcoma (DDLPS) is a unique subtype ofliposarcoma, which has obvious histological heterogeneity. In affected patients, the condition typically manifests as the dedifferentiation of high-grade histological morphology, but it may also manifest as the dedifferentiation of low-grade histological morphology. In some cases, unique histological or immunophenotypic characteristics are observed. We describe, herein, a rare case of dedifferentiated liposarcoma, in which the high-grade and low-grade dedifferentiated components coexisted with a relatively sharp transition in pathology.Case presentation: A 69-year-old woman with severe abdominal pain lasting for 1 hour presented to our hospital. Physical examination revealed a mobile large left abdominal mass, Magnetic resonance imaging (MRI) scan showed a huge mass with typical fat components and the non-fatty nodule in the left retroperitoneal cavity. After laparotomy, histologic analysis of the specimens could find the ALT/WDLPS and DDLPS components. Fluorescence in situ hybridization (FISH) analysis suggested the presence of MDM2 gene amplification. These findings supported a diagnosis of DDLPS.Conclusion: In our case, the high-grade and low-grade dedifferentiated components coexisted with a relatively sharp transition in pathology. We hypothesize that low-grade dedifferentiation may be a precursor to high-grade dedifferentiation. MRI images cannot distinguish the two components.

Efficiency of endoscopic use of cyanoacrylate and Lipidol® in the treatment of a high-grade bile leak after blunt liver trauma: a rare case report

Chirurgia ◽  
2019 ◽  
Vol 32 (5) ◽  
Author(s):  
Damiano Bisogni ◽  
Riccardo Naspetti ◽  
Luca Talamucci ◽  
Andrea Valeri ◽  
Roberto Manetti
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Bile Leak ◽  
Liver Trauma ◽  
High Grade ◽  
Rare Case Report ◽  
Blunt Liver Trauma

scholarly journals Low-Grade Endometrial Stromal Sarcoma in a 22-Year-Old Maiden Female: A Rare Case Report from Syria

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Lana Nseir ◽  
Georget Mansour ◽  
Junior Makhoul ◽  
Luna Skaf ◽  
Mohammad Ziad Dahhan ◽  
...  
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Treatment Plan ◽  
Endometrial Stromal Sarcoma ◽  
Abnormal Uterine Bleeding ◽  
Low Grade ◽  
Stromal Sarcoma ◽  
Rapid Enlargement ◽  
Rare Case Report ◽  
Immunohistochemical Studies

Endometrial stromal sarcoma (ESS) is a rare and challenging type of endometrial tumor, constituting only about 0.2% of all uterine malignancies and occurring in women 42–58 years of age. ESS is usually misdiagnosed as leiomyoma. They both have nonspecific symptoms, which makes the diagnosis of ESS difficult to achieve. As the ESS is infrequently encountered, optimal management is quite debatable. Here, we report a rare case of a 22-year-old Syrian female who presented with abnormal uterine bleeding; the preoperative diagnosis suggested leiomyoma while histopathological and immunohistochemical studies confirmed the diagnosis of LG-ESS stage IIA. Therefore, the treatment plan was shifted from a conservative myomectomy to a total hysterectomy with both adnexa. The aim of this case report is to draw attention to this uncommon tumor at young age of patients as well as to have awareness of the necessity to suspect this diagnosis especially with the presentation of rapid enlargement of uterine leiomyoma.

A Rare Case Report of Primary Low-Grade Endometrial Stromal Sarcoma (LGESS) of Ovary Infiltrating Bladder

2016 ◽  
Vol 14 (3) ◽  
Author(s):  
Senthil Kumar Ravichander ◽  
Ajay Krishna Boralkar ◽  
Neha Deepak Borde ◽  
Amol Rangnath Jadhav ◽  
Jyothi Sachin Mukhedkar
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Endometrial Stromal Sarcoma ◽  
Low Grade ◽  
Stromal Sarcoma ◽  
Rare Case Report

scholarly journals A maxillary ameloblastic fibrosarcoma tumor: a rare case report from Syria

2020 ◽  
Vol 2020 (8) ◽  
Author(s):  
Amjad Soltany ◽  
Ghazal Asaad ◽  
Rami Daher ◽  
Mouhannad Dayoub ◽  
Ali Khalil ◽  
...  
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Rare Case ◽  
Soft Tissue Sarcomas ◽  
Surgical Excision ◽  
Low Grade ◽  
Rare Case Report ◽  
Ameloblastic Fibrosarcoma ◽  
The Right

Abstract Ameloblastic fibrosarcoma (AFS) is a rare, aggressive malignant odontogenic tumor. AFS is seen most frequently in second and third decades of life. We are reporting a case of a low grade AFS in a 21-year-old male complaining of a painless swelling in the right side of the maxilla. The patient was treated with surgical excision followed by radiotherapy, which is considered the most effective approach for most of soft tissue sarcomas. AFS has a high-reported recurrence rate (up to 37%); therefore, long-term surveillance for recurrence is crucial.

scholarly journals Aggressive high-grade Ewing's sarcoma of maxilla: A rare case report

2018 ◽  
Vol 22 (4) ◽  
pp. 48
Author(s):  
Hema Keswani ◽  
TL Yogesh ◽  
Akshay Shetty ◽  
Diljith Rishi
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
High Grade ◽  
Rare Case Report
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