Specific Antibody Immunodeficiency Presenting With Streptococcal pneumonia-Induced Spontaneous Bacterial Peritonitis

Specific antibody immunodeficiency (SAD) is a primary immunodeficiency disorder characterized by normal levels of serum immunoglobulins (IgG, IgA, and IgM) associated with a dysfunctional immune response. SAD is associated with recurrent infections in the setting of an insufficient response to polysaccharide vaccinations. Streptococcus pneumoniae is a well-established cause of respiratory infections in SAD. However, there has been a paucity of evidence of pneumococcal peritonitis in SAD patients, being reported as spontaneous in acquired immunodeficiency such as AIDS. We report the first case of S. pneumoniae-induced peritonitis as the presenting sign for SAD.

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Spontaneous bacterial peritonitis and pneumonia caused by Bordetella bronchiseptica

The Journal of Infection in Developing Countries ◽

10.3855/jidc.2074 ◽

2011 ◽

Vol 6 (07) ◽

pp. 588-591 ◽

Cited By ~ 13

Author(s):

Nomonde Ritta Dlamini ◽

Ahmed Bhamjee ◽

Penelope Levick ◽

Evelyn Uniacke ◽

Husna Ismail ◽

...

Keyword(s):

Liver Disease ◽

Spontaneous Bacterial Peritonitis ◽

Human Infection ◽

Bordetella Bronchiseptica ◽

Bacterial Peritonitis ◽

Primary Peritonitis ◽

First Case ◽

Acquired Immunodeficiency ◽

Immunodeficiency Syndrome ◽

Common Infection

Bordetella bronchiseptica is a rare cause of invasive human infection. The most common infection in humans is the respiratory tract infection and it is usually associated with immunosuppression, particularly acquired immunodeficiency syndrome (AIDS). We report a case of a pneumonia and peritonitis in a 42-year-old female with alcoholic liver disease. The patient died despite treatment with antibiotics. This case illustrates the potential virulence of B. bronchiseptica in susceptible patients and to our knowledge it is the first case of primary peritonitis due to this organism.

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Leclercia adecarboxylata Causing Spontaneous Bacterial Peritonitis in a Child with Nephrotic Syndrome: A Case Report and Review of Literature

Journal of Laboratory Physicians ◽

10.1055/s-0040-1721162 ◽

2020 ◽

Vol 12 (03) ◽

pp. 222-224

Author(s):

Ijas Hassan ◽

Parakriti Gupta ◽

Pallab Ray ◽

Karalanglin Tiewsoh

Keyword(s):

Nephrotic Syndrome ◽

Spontaneous Bacterial Peritonitis ◽

Urine Analysis ◽

Opportunistic Pathogen ◽

Total Leukocyte Count ◽

Bacterial Peritonitis ◽

Flight Mass Spectrometry ◽

Source Of Infection ◽

First Case ◽

Identification Score

AbstractInfection is an important complication of childhood nephrotic syndrome (NS) and spontaneous bacterial peritonitis (SBP) is a frequently encountered one. We present a 7-year-old boy with NS who had decreased urine output, generalized body swelling, and abdominal pain. Urine analysis showed proteinuria of 50 mg/m2/d. Ascitic tap showed total leukocyte count of 100 cells/mm3, sugar of 67 mg/dL, and protein of 1.1 g/dL. Gram stain revealed gram-negative bacilli with pus cells and culture grown Leclercia adecarboxylata (LAD). LAD was identified using matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) with an identification score of 2.0. The organism showed good susceptibility to common antibiotics. The boy had no direct contact with livestock and the source of infection remains speculative. Devitalized skin because of massive edema seems to be the most plausible site of entry for the organism. Our patient was started on ceftriaxone and improved. LAD is a rare opportunistic pathogen, which belongs to Enterobacteriaceae and usually causes soft tissue infections. As far as we know, this is the first case where it has caused peritonitis in a child with NS. We also reviewed other pediatric cases.

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