Concurrent JAK2-Positive Myeloproliferative Disorder and Chronic Myelogenous Leukemia: A Novel Entity? A Case Report With Review of the Literature
2019 ◽
Vol 7
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pp. 232470961983232
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Keyword(s):
JAK2 V617F mutation and BCR-ABL translocation have been considered to be mutually exclusive. However, many cases where both hits coexisted have been reported. We have personally managed a case too. We believe this hybrid entity is underdiagnosed. Thus, we decided to shed light on this “double hit” disease to improve its diagnosis and optimize its treatment. We reviewed the English literature in PubMed since JAK2 discovery. We found 33 cases reported so far. We summarized patient characteristics and analyzed possible interactions between JAK2 and BCR-ABL clones.
2016 ◽
Vol 9
(1)
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pp. 29-33
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Keyword(s):
2013 ◽
Vol 54
(7)
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pp. 1567-1568
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2009 ◽
Vol 33
(11)
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pp. e178-e180
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1999 ◽
Vol 26
(1)
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pp. 56-62
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Keyword(s):
2000 ◽
Vol 66
(1)
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pp. 57-58
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2017 ◽
Vol 112
◽
pp. S1094-S1095
2014 ◽
Vol 142
(suppl_1)
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pp. A126-A126
Keyword(s):
2008 ◽
Vol 88
(2)
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pp. 243-245
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