scholarly journals The Magnitude of the Health and Economic Impact of Increased Organ Donation on Patients With End-Stage Renal Disease

2021 ◽  
Vol 6 (2) ◽  
pp. 238146832110634
Author(s):  
Huey-Fen Chen ◽  
Hayatt Ali ◽  
Wesley J. Marrero ◽  
Neehar D. Parikh ◽  
Mariel S. Lavieri ◽  
...  
Keyword(s):  
United States ◽  
Renal Disease ◽  
Economic Impact ◽  
End Stage Renal Disease ◽  
Deceased Donor ◽  
The United States ◽  
Kidney Donation ◽  
Life Years ◽  
Stage Renal Disease ◽  
End Stage

Objectives. There are several approaches such as presumed consent and compensation for deceased donor organs that could reduce the gap between supply and demand for kidneys. Our objective is to evaluate the magnitude of the economic impact of policies to increase deceased donor organ donation in the United States. Methods. We built a Markov model and simulate an open cohort of end-stage renal disease patients awaiting kidney transplantation in the United States over 20 years. Model inputs were derived from the United States Renal Data System and published literature. We evaluate the magnitude of the health and economic impact of policies to increase deceased donor kidney donation in the United States. Results. Increasing deceased kidney donation by 5% would save $4.7 billion, and gain 30,870 quality-adjusted life years over the lifetime of an open cohort of patients on dialysis on the waitlist for kidney transplantation. With an increase in donations of 25%, the cost saved was $21 billion, and 145,136 quality-adjusted life years were gained. Policies increasing deceased kidney donation by 5% could pay donor estates $8000 or incur a onetime cost of up to $4 billion and still be cost-saving. Conclusions. Increasing deceased kidney donation could significantly impact national spending and health for end-stage renal disease patients.

scholarly journals Pre-End-Stage Renal Disease Care Not Associated with Dialysis Facility Neighborhood Poverty in the United States

2014 ◽  
Vol 39 (1) ◽  
pp. 50-58 ◽  
Author(s):  
Laura C. Plantinga ◽  
Min Kim ◽  
Margarethe Goetz ◽  
David G. Kleinbaum ◽  
William McClellan ◽  
...  
Keyword(s):  
United States ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
The United States ◽  
Neighborhood Poverty ◽  
Dialysis Facility ◽  
Stage Renal Disease ◽  
End Stage

Abstract MP10: Increasing Obesity Prevalence in the United States End-stage Renal Disease Population

Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Brittany Shelton ◽  
Deanna McWilliams ◽  
Rhiannon D Reed ◽  
Margaux Mustian ◽  
Paul MacLennan ◽  
...  
Keyword(s):  
United States ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
The United States ◽  
Obesity Prevalence ◽  
The Us ◽  
Prevalence Of Obesity ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Background: Obesity has become a national epidemic, and is associated with increased risk for comorbid diseases including end-stage renal disease (ESRD). Among ESRD patients, obesity may improve dialysis-survival but decreases likelihood of transplantation, and as such, obesity prevalence may directly impact growth of the incident dialysis population. Methods: Incident adult ESRD patients with complete body mass index (BMI, kg/m 2 ) data were identified from the United States Renal Data System from 01/01/1995-12/31/2010 (n=1,822,598). Data from the Behavioral Risk Factor Surveillance System of the Centers for Disease Control and Prevention (n=4,303,471) represented the US population when weighted. Trends in BMI and obesity classes I (BMI of 30-34.9), II (BMI of 35-39.9), and III (BMI ≥40) were examined by year of dialysis initiation. Trends in median BMI slope were compared between the ESRD and US populations using linear regression. Results: Median BMI of ESRD patients in 1995 was 24.2 as compared to 28.0 in 2010, a 15.7% increase, while the US population’s median BMI increased from 24.2 in 1995 to 25.6 in 2010, a 5.8% increase. Comparable trends were noted with respect to prevalence of obesity classes I, II, and III (Table). BMI increase among the ESRD population was significantly more rapid than among the US population (β: 0.15, 95% CI: 0.14-0.17, p<0.001) (Figure). Conclusion: The median BMI of ESRD patients and prevalence of obesity among ESRD patients is increasing more rapidly than the US population. Given the increased dialysis-survival and decreased likelihood of transplantation associated with obesity, healthcare costs will likely increase, and thus, future research should be directed at examining medical expenditures.

Increasing Obesity Prevalence in the United States Pediatric End-Stage Renal Disease Population

2018 ◽  
Vol 102 ◽  
pp. S844
Author(s):  
Brittany Shelton ◽  
Deanna M McWilliams ◽  
Paul A MacLennan ◽  
Rhiannon D Reed ◽  
Margaux N Mustian ◽  
...  
Keyword(s):  
United States ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
The United States ◽  
Obesity Prevalence ◽  
Stage Renal Disease ◽  
End Stage

The Impact of End-Stage Renal Disease Transfusion Demand on Blood Utilization and Blood Supply in the United States

2012 ◽  
Vol 3 (2) ◽  
pp. e67-e77
Author(s):  
Christopher S. Hollenbeak ◽  
Matthew Gitlin ◽  
Brian Custer ◽  
William M. McClellan ◽  
Axel Hofmann ◽  
...  
Keyword(s):  
United States ◽  
Renal Disease ◽  
Blood Supply ◽  
End Stage Renal Disease ◽  
The United States ◽  
Blood Utilization ◽  
Stage Renal Disease ◽  
End Stage ◽  
The Impact

scholarly journals Trends in Anemia Care in Older Patients Approaching End-Stage Renal Disease in the United States (1995-2010)

2014 ◽  
Vol 174 (5) ◽  
pp. 699 ◽  
Author(s):  
Wolfgang C. Winkelmayer ◽  
Aya A. Mitani ◽  
Benjamin A. Goldstein ◽  
M. Alan Brookhart ◽  
Glenn M. Chertow
Keyword(s):  
United States ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Older Patients ◽  
The United States ◽  
Stage Renal Disease ◽  
End Stage
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