scholarly journals Third-party CD4+ invariant natural killer T cells protect from murine GVHD lethality

Blood ◽  
2015 ◽  
Vol 125 (22) ◽  
pp. 3491-3500 ◽  
Author(s):  
Dominik Schneidawind ◽  
Jeanette Baker ◽  
Antonio Pierini ◽  
Corina Buechele ◽  
Richard H. Luong ◽  
...  
Keyword(s):  
T Cells ◽  
Natural Killer ◽  
Natural Killer T Cells ◽  
Third Party ◽  
Low Doses ◽  
Inkt Cells ◽  
Key Points ◽  
Killer T Cells ◽  
Invariant Natural Killer ◽  
Natural Killer T

Key Points Low doses of adoptively transferred third-party CD4+ iNKT cells protect from lethal GVHD while preserving graft-versus-tumor effects. Third-party CD4+ iNKT cells are rejected early after transplantation yet protect from GVHD lethality through donor Tregs.

scholarly journals Invariant natural killer T cells ameliorate murine chronic GVHD by expanding donor regulatory T cells

Blood ◽  
2017 ◽  
Vol 129 (23) ◽  
pp. 3121-3125 ◽  
Author(s):  
Jing Du ◽  
Katelyn Paz ◽  
Govindarajan Thangavelu ◽  
Dominik Schneidawind ◽  
Jeanette Baker ◽  
...  
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Natural Killer ◽  
Chronic Gvhd ◽  
Natural Killer T Cells ◽  
Low Doses ◽  
Key Points ◽  
Killer T Cells ◽  
Invariant Natural Killer ◽  
Natural Killer T

Key Points Low doses of donor iNKT infusion prevent and reverse murine cGVHD. iNKT efficacy in treating established cGVHD is dependent on donor Treg expansion.

scholarly journals CD4+ invariant natural killer T cells protect from murine GVHD lethality through expansion of donor CD4+CD25+FoxP3+ regulatory T cells

Blood ◽  
2014 ◽  
Vol 124 (22) ◽  
pp. 3320-3328 ◽  
Author(s):  
Dominik Schneidawind ◽  
Antonio Pierini ◽  
Maite Alvarez ◽  
Yuqiong Pan ◽  
Jeanette Baker ◽  
...  
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Natural Killer ◽  
Natural Killer T Cells ◽  
Low Doses ◽  
Inkt Cells ◽  
Alloreactive T Cells ◽  
Key Points ◽  
Killer T Cells ◽  
Invariant Natural Killer

Key Points Low doses of adoptively transferred donor CD4+ iNKT cells protect from GVHD while preserving graft-versus-tumor effects. Donor CD4+ iNKT cells inhibit proliferation of alloreactive T cells and promote robust expansion of donor Tregs.

scholarly journals Activation of invariant natural killer T cells by alpha-galactosylceramide ameliorates doxorubicin-induced cardiotoxicity in mice

2020 ◽  
Vol 27 (19) ◽  
pp. 2358-2361
Author(s):  
Yoshikuni Obata ◽  
Naoki Ishimori ◽  
Akimichi Saito ◽  
Shintaro Kinugawa ◽  
Takashi Yokota ◽  
...  
Keyword(s):  
T Cells ◽  
Natural Killer ◽  
Natural Killer T Cells ◽  
Killer T Cells ◽  
Invariant Natural Killer ◽  
Natural Killer T

Effect of invariant natural killer T cells with IL-5 and activated IL-6 receptor in ventilator-associated lung injury in mice

2013 ◽  
Vol 40 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Yuka Shiga ◽  
Ryuichi Sugamata ◽  
Chiaki Iwamura ◽  
Tomokazu Nagao ◽  
Jun Zao ◽  
...  
Keyword(s):  
T Cells ◽  
Lung Injury ◽  
Natural Killer ◽  
Natural Killer T Cells ◽  
Killer T Cells ◽  
Invariant Natural Killer ◽  
Natural Killer T

scholarly journals Increased frequency of circulating invariant natural killer T cells in malignant pleural mesothelioma patients

2012 ◽  
Vol 13 (9) ◽  
pp. 702-711 ◽  
Author(s):  
Emanuela Altomare ◽  
Silvia Fallarini ◽  
Gabriele Biaggi ◽  
Elisabetta Gattoni ◽  
Mario Botta ◽  
...  
Keyword(s):  
T Cells ◽  
Natural Killer ◽  
Malignant Pleural Mesothelioma ◽  
Natural Killer T Cells ◽  
Pleural Mesothelioma ◽  
Killer T Cells ◽  
Invariant Natural Killer ◽  
Natural Killer T

scholarly journals Contribution of Invariant Natural Killer T Cells to Skin Wound Healing

2015 ◽  
Vol 185 (12) ◽  
pp. 3248-3257 ◽  
Author(s):  
Hiromasa Tanno ◽  
Kazuyoshi Kawakami ◽  
Masae Ritsu ◽  
Emi Kanno ◽  
Aiko Suzuki ◽  
...  
Keyword(s):  
Wound Healing ◽  
T Cells ◽  
Natural Killer ◽  
Natural Killer T Cells ◽  
Skin Wound ◽  
Skin Wound Healing ◽  
Killer T Cells ◽  
Invariant Natural Killer ◽  
Natural Killer T
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