scholarly journals Case Report: Splenectomy in Sickle Cell Anemia: Report of a Case and Review of the Literature

Blood ◽  
1951 ◽  
Vol 6 (4) ◽  
pp. 365-371 ◽  
Author(s):  
DONALD SHOTTON ◽  
CHARLES L. CROCKETT ◽  
BYRD S. LEAVELL
Keyword(s):  
Case Report ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
General Condition ◽  
Marked Improvement ◽  
Therapeutic Procedure ◽  
Review Of The Literature

Abstract 1. A case of sickle cell anemia who had numerous hemolytic crises and also hypersplenic effects such as pancytopenia was treated by splenectomy with marked improvement in general condition and in the blood. The literature relating to this subject is reviewed. Those cases with the largest spleens appear to have shown the most striking degrees of improvement. 2. In cases of sickle cell anemia showing various indications of hypersplenism, and excessive hemolysis, splenectomy may be a rational therapeutic procedure.

Myonecrosis in Sickle Cell Anemia: Case Report and Review of the Literature

2004 ◽  
Vol 97 (9) ◽  
pp. 894-896 ◽  
Author(s):  
Perla Vicari ◽  
Ruth Achkar ◽  
Kathia R.B. Oliveira ◽  
Milton L. Miszpupten ◽  
Artur R.C. Fernandes ◽  
...  
Keyword(s):  
Case Report ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Review Of The Literature

scholarly journals Research Article GSTT1 null genotype in sickle cell anemia and blood transfusion recurrence – a case report

2019 ◽  
Vol 18 (2) ◽  
Author(s):  
O.S. Dias Neto ◽  
K.S.F. e Silva ◽  
A.M. Barbosa ◽  
D.A. Rodrigues ◽  
M.H. Lagares ◽  
...  
Keyword(s):  
Case Report ◽  
Blood Transfusion ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Research Article

SICKLE CELL ANEMIA: CASE REPORT

1925 ◽  
Vol 18 (11) ◽  
pp. 795-796 ◽  
Author(s):  
S Chaille Jamison
Keyword(s):  
Case Report ◽  
Sickle Cell ◽  
Sickle Cell Anemia

Splenomegaly with Hypersplenism in Sickle Cell Anemia Treated by Radiation—Case Report

PEDIATRICS ◽  
1971 ◽  
Vol 48 (3) ◽  
pp. 457-458
Author(s):  
Annemarie Sommer ◽  
Stella B. Kontras
Keyword(s):  
Cell Survival ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Marked Improvement ◽  
Costal Margin ◽  
Red Cell ◽  
Older Children ◽  
Before And After ◽  
Red Cell Survival ◽  
Survival Studies

The incidence of splenomegaly in sickle cell anemia (defined as a spleen easily palpated below the costal margin in quiet respiration) appears to be around 10% after 10 years of age. Persistent splenomegaly in older children is rare and frequently is associated with hypersplenism. Splenectomy has been the treatment of choice in several reported cases based on red cell survival studies before and after splenectomy.1-3 Removal of the spleen has been found to be associated with marked improvement of previously very shortened red cell survival. We want to report the case of a 12-year-old boy with sickle cell anemia, splenomegaly, and sickle cell heart disease who was treated by radiation therapy for his enlarged spleen because of hypersplenism.

Sickle Cell Anemia in Two White American Children: Essential Laboratory Criteria for Diagnosis

PEDIATRICS ◽  
1979 ◽  
Vol 63 (2) ◽  
pp. 242-246
Author(s):  
Peter A. Noronha ◽  
George R. Honig
Keyword(s):  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Laboratory Diagnosis ◽  
White Americans ◽  
Review Of The Literature ◽  
Cell Disease ◽  
White American ◽  
Precise Diagnosis ◽  
American Children ◽  
Criteria For Diagnosis

A number of hematologic disorders share diagnostic and clinical features of sickle cell anemia but have significantly different genetic implications and prognosis. Because of these differences, the establishment of a precise diagnosis is essential for the child in whom any form of sickle cell disease is identified. To illustrate the requirements for a definitive laboratory diagnosis of sickle cell anemia, this report presents the approach to establishing this diagnosis in two white American patients. From a review of the literature, these patients appear to be the only white Americans with sickle cell anemia in whom this diagnosis has been unequivocally established.

scholarly journals Subperiosteal hematoma and orbital compression syndrome following minor frontal trauma in sickle cell anemia: case report

2008 ◽  
Vol 71 (2) ◽  
pp. 262-264 ◽  
Author(s):  
Fernando Procianoy ◽  
Mauro Brandão Filho ◽  
Antonio Augusto Velasco e Cruz ◽  
Victor Marques Alencar
Keyword(s):  
Case Report ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Compression Syndrome
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