Marrow transplantation for children with acute lymphoblastic leukemia in second remission
Keyword(s):
Abstract Fifty-seven children between the ages of 3 and 17 years with acute lymphoblastic leukemia (ALL) in chemotherapy-induced second bone marrow remission were given cyclophosphamide, total body irradiation, and bone marrow transplants from HLA-matched donors. Sixteen died of transplant- related complications. Eighteen relapsed between 56 and 833 days after transplantation, and 16 died of leukemia. Two survive in remission off treatment following chemotherapy. Twenty-three survive in continuous remission from 1.4 to 10.4 years after transplantation and the actuarial analysis shows disease-free survival of 40% with a plateau extending from 2.5 to 10.4 years.
2004 ◽
Vol 27
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pp. 477-479
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1989 ◽
Vol 7
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pp. 747-753
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2000 ◽
Vol 18
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pp. 340-340
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2006 ◽
Vol 24
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pp. 3150-3156
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2001 ◽
Vol 6
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pp. 48-49