scholarly journals Factors affecting adherence with treatment advice in a clinical trial of patients with severe asthma

2021 ◽  
pp. 2100768
Author(s):  
John Busby ◽  
John G. Matthews ◽  
Rekha Chaudhuri ◽  
Ian D. Pavord ◽  
Timothy C. Hardman ◽  
...  

BackgroundUnderstanding why patients with severe asthma do not follow healthcare provider (HCP) advice to adjust treatment is critical to achieving personalised disease management.MethodsWe reviewed patient choice to follow HCP advice to adjust asthma treatment in a randomised, controlled, single-blind (study participant), multi-centre, parallel group 48-week clinical study comparing biomarker directed treatment adjustment to standard care in severe asthma.ResultsOf 1572 treatment advisories (301 participants), instructions were followed in 1377 cases (87.6%). Patients were more likely to follow advice to remain on treatment (96.7%) than to either reduce (70.3%) or increase (67.1%) their treatment, with 64% of patients following all treatment advice. Multivariate analysis associated belonging to an ethnic minority group (OR: 3.10; 95% CI: 1.68, 5.73) and prior study medication changes (≥2 OR: 2.77, 95% CI: 1.51, 5.10) with failure to follow treatment advice. In contrast, emergency room attendance in the prior year (OR: 0.54, 95% CI: 0.32, 0.92) was associated with following treatment advice. The largest effect was seen with transition onto or off oral corticosteroids (OR: 29.28; 95% CI: 16.07, 53.36) when compared to those requested to maintain treatment. Centre was also an important determinant regarding the likelihood of patients to follow treatment advice.ConclusionsBelonging to an ethnic minority group and multiple prior treatment adjustments were associated with not following HCP treatment advice. Patients also responded differently to HCP advice across UK specialist centres. These findings have implications for generalisability for models of care in severe asthma and require further focussed studies.

Author(s):  
Meenaxi Barkataki-Ruscheweyh

In the concluding chapter, I discuss the various strategies that the Tangsa use in Assam to survive as a small ethnic minority group and how performing identity and ethnicity at festivals can be considered to be yet one more such strategy. This leads to a discussion of Tangsa identity, ethnicity, and culture as well as the role of the state and the Assamese ‘other’ in defining what it means to be Tangsa. In a ‘Taking Stock’ section, I list all my shortcomings, and also all that that still needs to be done before some amount of clarity can be achieved in understanding the complex Tangsa picture. The concluding section summarizes my findings to make clear the underlying and undeniable connection between performing ethnicity and negotiating marginalization.


2010 ◽  
Vol 125 (4) ◽  
pp. 581-585 ◽  
Author(s):  
Bo-feng Zhu ◽  
Chun-mei Shen ◽  
Hong-dan Wang ◽  
Guang Yang ◽  
Jiang-wei Yan ◽  
...  

2021 ◽  
Vol 8 (2) ◽  
pp. 21
Author(s):  
Bizuayehu Dengechi Dachachi ◽  
Nigatuwa Worku Woyessa ◽  
Fisseha Mikre Weldmeskel

This study examined the level of psychological well-being between the Ethnic Minority group, commonly called “Manjo,” and the majority group called “Gomero.” Psychological well-being questionnaires were administered to a sample of 298 (independent sample from both groups). The findings demonstrated that the non-Manjo (Gomero) Ethnic group possessed a considerably high level of psychological well-being. Statistical differences were found in participants’ psychological well-being across Ethnic groups. According to the results, participants from the Manjo Ethnic Minority group had a lower level of psychological well-being (M = 211.27, SD = 17.51) compared to the majority (Gomero). A statistically significant variation in psychological well-being (theoretically embodied across a broad spectrum of measurement units) among the two independent study groups was reflected. 


Hemoglobin ◽  
2019 ◽  
Vol 43 (4-5) ◽  
pp. 249-253
Author(s):  
Tuan Mai Anh ◽  
Kanokwan Sanchaisuriya ◽  
Giang Nguyen Kieu ◽  
Dung Nguyen Tien ◽  
Huong Bui Thi Thu ◽  
...  

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