A randomized study to compare the efficacy and safety of extended-release and immediate-release tramadol HCl/acetaminophen in patients with acute pain following total knee replacement

2014 ◽  
Vol 31 (1) ◽  
pp. 75-84 ◽  
Author(s):  
Yong-Beom Park ◽  
Chul-Won Ha ◽  
Sung-Do Cho ◽  
Myung-Chul Lee ◽  
Ju-Hong Lee ◽  
...  
Keyword(s):  
Total Knee Replacement ◽  
Knee Replacement ◽  
Acute Pain ◽  
Extended Release ◽  
Randomized Study ◽  
Immediate Release ◽  
Efficacy And Safety ◽  
Total Knee

scholarly journals Use of Enoxaparin and Dabigatran for Thrombosis Prevention After Total Knee Replacement

2012 ◽  
Vol 19 (2) ◽  
pp. 61-64
Author(s):  
V. Yu Murylev ◽  
Y. A Rukin ◽  
P. M Elizarov ◽  
A. G Zhuchkov ◽  
D. I Terentiev
Keyword(s):  
Total Knee Replacement ◽  
Enoxaparin Sodium ◽  
Knee Replacement ◽  
Vena Cava ◽  
Preventive Measure ◽  
Early Postoperative Period ◽  
Peroral Administration ◽  
Efficacy And Safety ◽  
Significant Difference ◽  
Total Knee

Comparative analysis of dabigatran etaxilate and enoxaparin sodium use for prevention of vena cava inferior system thrombosis in patients after total knee replacement in early postoperative period was performed. In 74 patients (1 st group) dabigatran etaxilate and in 127 (2 nd group) enoxaparin sodium was used as a preventive measure. The rate of thrombosis made up 1.35% and 2.4% in the first and second groups, respectively. No significant difference in the volume of perioperative blood loss between the groups was noted. No other hemorrhagic complications were observed. It was shown that in more convenient peroral administration the dabigatran etaxilate efficacy and safety was comparable to enoxaparin sodium.

Sign in / Sign up

Export Citation Format

Share Document