scholarly journals Granulomatous hepatitis due to Bartonella henselae infection in an immunocompetent patient

2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Thomas R VanderHeyden ◽  
Sherri L Yong ◽  
Edward B Breitschwerdt ◽  
Ricardo G Maggi ◽  
Amanda R Mihalik ◽  
...  
2021 ◽  
Vol 13 (3) ◽  
pp. 611-618
Author(s):  
Elsa Alves Branco ◽  
Raquel Duro ◽  
Teresa Brito ◽  
António Sarmento

Intra-vesical instillation of bacillus Calmette–Guérin (BCG) is an important treatment modality of superficial bladder cancer. It is usually well tolerated, although some adverse reactions can occur. One possible yet rare complication is granulomatous hepatitis, that is thought to be caused either by BCG infection or a hypersensitivity reaction to the bacillus. We present a case of a 79-year-old apparently immunocompetent patient who developed granulomatous hepatitis a few months after BCG administration for bladder cancer immunotherapy. It is important to notice that acid-fast smears and cultures are often negative, and these should not exclude diagnosis nor delay treatment. Our case highlights the importance of clinical suspicion and prompt initiation of appropriate treatment.


Cureus ◽  
2021 ◽  
Author(s):  
Adel Muhanna ◽  
Faisal M Nimri ◽  
Zaid A Almomani ◽  
Laith Al Momani ◽  
Alisa Likhitsup

2013 ◽  
Vol 62 (7) ◽  
pp. 1081-1085 ◽  
Author(s):  
Maria Carla Liberto ◽  
Giovanni Matera ◽  
Angelo G. Lamberti ◽  
Angela Quirino ◽  
Giorgio S. Barreca ◽  
...  

Systemic Bartonella henselae infections are unusual in immunocompetent adults. However, here we report one such case of bartonellosis in a 34-year-old patient, who presented with fever and multinodular splenomegaly. We also describe a novel method of identifying Bartonella henselae by real-time quantitative polymerase chain reaction and sequencing of amplified products. This could prevent splenic bartonellosis being mistaken for lymphoma and thereby avert unnecessary splenectomy.


2021 ◽  
Vol 1 (2) ◽  
pp. 84-87
Author(s):  
Servet Öztürk ◽  
Derya Öztürk Engin ◽  
Semra Toprak Kavas ◽  
Onur Çolak ◽  
Adnan Somay ◽  
...  

2020 ◽  
Vol 7 (09) ◽  
pp. 4966-4972
Author(s):  
Fotis Konstantinou, ◽  
Ioanna Skrapari ◽  
Asimoula Megkou ◽  
Evangelos Kokkinakis

Purpose: Cat-scratch disease is caused by Bartonella henselae infection and it commonly presents in children with a mild cutaneous lesion and adjacent lymphadenitis. It has rarely been observed that it can present as a disseminated infection, such as encephalitis or pneumonia. We present a case report of a 35-year old, immunocompetent, patient who suffered pneumonia and encephalitis, resulting from Bartonella henselae infection. We also present a review of the literature published regarding this rare complication. Methods: We’ve searched the literature in the databases of Pubmed and Google Scholar to find articles that report pulmonary presentations of cat-scratch disease. Results: We’ve found only 16 other reported similar cases with pulmonary involvement in cat-scratch disease. Conclusions: Pulmonary presentation in cat-scratch disease is an uncommon presentation of a common disease, and it should be ruled out, even in cases it seems unlikely.  


2019 ◽  
Vol 37 (2) ◽  
pp. 292-295
Author(s):  
Sonu Kumari Agrawal ◽  
Prasenjit Das ◽  
Shalimar ◽  
Gupta Swatantra ◽  
Rama Chaudhry

2013 ◽  
Vol 70 (1) ◽  
pp. 72-76 ◽  
Author(s):  
Miroslav Kojic ◽  
Dragan Mikic ◽  
Darko Nozic ◽  
Lidija Zolotarevski

Introduction. Cat scratch disease (CSD) is an acute infectious disease with benign course caused by the bacteria Bartonella henselae. Clinically, it is usually manifested as regional lymphadenopathy and mild infective syndrome. Rare forms of the disease which usually occur in immunocompromised presons are: encephalitis, transverse myelitis, neuroretinitis, granulomatosus conjunctivitis, arthritis, hepatitis etc. Case report. We presented an atypical form of cat scratch disease in a young immunocompetent female person. The disease was manifested with prolonged fever, rash, purulent lymphadenitis and hepatitis. The diagnosis was based on characteristic patohystological finding and exclusion of the other causes of lymphadenopathy. The patient was treated by antibiotics for a few weeks, with surgical incision and drainage of the purulent lymphadenitis. Conclusion. Atypical forms of CSD could be an important differential-diagnostic problem, especially if there is no opportunity for serological confirmation of the disease.


2011 ◽  
Vol 106 ◽  
pp. S280
Author(s):  
Thomas VanderHeyden ◽  
Claus Fimmel ◽  
Edward Breitschwerdt ◽  
Jorge Parada ◽  
Sherri Yong ◽  
...  

2004 ◽  
Vol 36 (4) ◽  
pp. 316-317 ◽  
Author(s):  
Peter Schiellerup ◽  
Karen Krogfelt ◽  
Åse Bengård Andersen

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