scholarly journals High degree of efficacy in the treatment of cyclic vomiting syndrome with combined co-enzyme Q10, L-carnitine and amitriptyline, a case series

BMC Neurology ◽  
2011 ◽  
Vol 11 (1) ◽  
Author(s):  
Richard G Boles
Keyword(s):  
Case Series ◽  
Cyclic Vomiting Syndrome ◽  
High Degree ◽  
Cyclic Vomiting

scholarly journals A case series of cyclic vomiting syndrome in paediatric patients at a tertiary care hospital in Chennai, Tamil Nadu, India

2018 ◽  
Vol 6 (1) ◽  
pp. 118
Author(s):  
Ruchi R. Mittal ◽  
Latha Ravichandran ◽  
Elayaraja Elayaraja
Keyword(s):  
Tamil Nadu ◽  
Tertiary Care ◽  
Case Series ◽  
Cyclic Vomiting Syndrome ◽  
Care Hospital ◽  
Severe Nausea ◽  
Paediatric Patients ◽  
The Mean ◽  
Cyclic Vomiting

Background: Cyclic vomiting syndrome is an increasingly recognized disorder with sudden, repeated episodes of severe nausea, vomiting, and physical exhaustion that occur with no apparent cause. It is more common in children than adults. However, we don’t often see a diagnosis of cyclic vomiting syndrome being made. Hereby we report 7 cases of cyclical vomiting.Methods: This is a retrospective study. Medical records of 5 years were review and consecutive paediatric patients discharged with a diagnosis of cyclic vomiting syndrome were identified, data collected and analysed.Results: Total of 7 cases were found, all of which were adolescents. The mean age was 13.28. 57.14% (4) were females and 42.86% (3) were boys. 42.86% (3) presented with complications. 14.28% (1) had an association with menstrual cycles and 14.28% (1) had an association with psychological stress.Conclusions: Cyclic vomiting syndrome should be kept in mind when a child presents with multiple episodes of vomiting, especially when repeated admissions have been made for the same. Early diagnosis and treatment can improve the quality of life.

Zonisamide or Levetiracetam for Adults With Cyclic Vomiting Syndrome: A Case Series

2007 ◽  
Vol 5 (1) ◽  
pp. 44-48 ◽  
Author(s):  
Ray E. Clouse ◽  
Gregory S. Sayuk ◽  
Patrick J. Lustman ◽  
Chandra Prakash
Keyword(s):  
Case Series ◽  
Cyclic Vomiting Syndrome ◽  
Cyclic Vomiting

scholarly journals Cyclic vomiting syndrome: a case series and review of the literature

2016 ◽  
Vol 9 (1) ◽  
pp. 2-9 ◽  
Author(s):  
Jessica Shearer ◽  
Pavit Luthra ◽  
Alexander C Ford
Keyword(s):  
Medical Records ◽  
Tricyclic Antidepressants ◽  
Case Series ◽  
Response To Treatment ◽  
Cyclic Vomiting Syndrome ◽  
Review Of The Literature ◽  
Duration Of Symptoms ◽  
History Of ◽  
Cannabis Smoking ◽  
Cyclic Vomiting

ObjectiveCyclic vomiting syndrome (CVS) is under-recognised. Treatment is difficult as the pathophysiology is incompletely understood. We report our experience of treating patients with amitriptyline, and review the literature to summarise symptoms and associated features, epidemiology, potential pathophysiological mechanisms, differential diagnoses and treatment.DesignConsecutive adult patients with CVS were identified during a 5-year period from January 2010 until December 2015. Medical records were reviewed retrospectively, and age and sex of the patient, symptoms, associated features and response to treatment with amitriptyline were recorded.SettingA luminal gastroenterology clinic at a teaching hospital.ResultsSeventeen patients were identified (mean age 29.8 years, 13 (76.5%) female). Five had a history of cannabis use. Duration of symptoms prior to diagnosis ranged from 5 months to 15 years. Fourteen patients commenced amitriptyline, and in eight (57.1%) symptoms either ceased entirely or improved. Review of the literature suggested the prevalence of CVS was 0.5%. Symptoms are stereotypical, with acute episodes of nausea and vomiting, interspersed by periods when the patient is symptom-free. Proposed pathophysiologies include neuroendocrine dysfunction, mutations in mitochondrial DNA and re-intoxication effects from cannabis stored in fat tissues. Treatment during the acute phase is supportive, with rehydration, sedation and antiemetics. Prophylaxis to prevent future attacks with antihistamines, antimigraine drugs, antiepileptics and tricyclic antidepressants may be beneficial. Complete cessation of cannabis smoking should be advised.ConclusionsDiagnosis of CVS is often delayed in adults. Once identified, patients respond well to amitriptyline.

scholarly journals A Case Series of Cyclic Vomiting Syndrome in Children at Pediatric Gastroenterology Clinic in Benghazi Medical Center

2021 ◽  
pp. 56-62
Author(s):  
Omelkhir I. Elbanoni ◽  
Ahlam A. Snaalla ◽  
Huda A. Elabbud ◽  
Tahani A. Asnedel
Keyword(s):  
Pediatric Patients ◽  
Medical Center ◽  
Case Series ◽  
Sudden Onset ◽  
Response To Treatment ◽  
Cyclic Vomiting Syndrome ◽  
Pediatric Gastroenterology ◽  
Prodromal Symptoms ◽  
Duration Of Symptoms ◽  
Cyclic Vomiting

Background: Cyclic vomiting syndrome (CVS) is a functional disorder characterized by repeated episodes of sudden onset of intense vomiting that is followed by symptom-free periods. The diagnosis is based on the fulfillment of Rome IV criteria. The Cyclic vomiting syndrome shares similar features to migraine headaches. It is under-recognized and often misdiagnosed with significant delays in therapy. Aims: To evaluate the clinical characteristic of pediatric patients diagnosed with cyclic vomiting syndrome in our institution and their response to treatment. Patients and Methods: A prospective case series of 13 pediatric patients with cyclic vomiting syndrome seen between period of November 2018 to November 2020 at pediatric gastroenterology outpatient’s clinic in Benghazi medical center. All relevant data including; age and sex, age of presentation, duration of symptoms, age at diagnosis, presence of aura or prodromal symptoms, patient or family history of headache, treatment and their response to treatment were collected. Results: The mean age for diagnosis was 112.2 ± 37.7 months. 46.2% of patients had recognizable prodromal symptoms. Patients with CVS had intense nausea and persistent vomiting that requiring hospitalization. In 44.4% of patients had stopped the episodes as a response to propranolol. Conclusion: Cyclic Vomiting Syndrome (CVS) is a functional, an under-recognized, and misdiagnosed episodic. The illness is characterized by stereotypical pattern of vomiting leading to frequent hospitalizations.

scholarly journals Cannabinoid hyperemesis syndrome: definition, pathophysiology, clinical spectrum, insights into acute and long-term management

2020 ◽  
Vol 68 (8) ◽  
pp. 1309-1316
Author(s):  
Mahesh Gajendran ◽  
Joshua Sifuentes ◽  
Mohammad Bashashati ◽  
Richard McCallum
Keyword(s):  
Symptom Control ◽  
Well Being ◽  
Clinical Entity ◽  
Cyclic Vomiting Syndrome ◽  
Cannabinoid Hyperemesis Syndrome ◽  
Acute Attacks ◽  
Hot Baths ◽  
Term Management ◽  
Cyclic Vomiting

Although cannabinoid hyperemesis syndrome (CHS) was first reported more than 15 years ago, it still remains an unfamiliar clinical entity among physicians worldwide. CHS is categorized by Rome IV classification as a functional gastroduodenal disorder. It is characterized by stereotypical episodic vomiting in the setting of chronic, daily cannabis use, with cycles decreasing by the cessation of cannabis. CHS is also associated with abdominal pain reduced by hot baths and showers with comparative well-being between attacks. Thus, its clinical presentation resembles ‘classic’ cyclic vomiting syndrome, but eliciting a cannabis history is crucial in diagnosing this entity. In acute attacks, parenteral benzodiazepines are very effective. For prevention and long-term management, tricyclic antidepressants such as amitriptyline are the mainstay of therapy requiring doses in the range of 50–200 mg/d to achieve symptom control. In addition, counseling to achieve marijuana cessation, accompanied by antianxiety medications, is necessary for sustaining clinical outcomes. Once the patient is in remission and off marijuana for a period of 6–12 months, then tapering the dose of amitriptyline can be implemented, with the goal of no therapy being achieved in the majority of patients over time. With the legalization of marijuana in many states, CHS will become an increasingly prevalent clinical entity, so educating about CHS is an important goal, particularly for emergency department physicians who generally first encounter these patients.

CO17 FLUNARIZINE IN THE TREATMENT OF CYCLIC VOMITING SYNDROME (CVS)

2012 ◽  
Vol 44 ◽  
pp. S248
Author(s):  
R. Mallamace ◽  
D. Comito ◽  
S. Cardile ◽  
A. Chiaro ◽  
C. Romano
Keyword(s):  
Cyclic Vomiting Syndrome ◽  
Cyclic Vomiting
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